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Table 1.

Adverse events in healthy volunteers after a single dose of resveratrol

Nature of event*No. individuals
Dose level (g)
0.51.02.55.0
Unlikely to be drug related     
    Raised urea 
    Raised creatinine 
    Low total protein 
    Raised albumin 
    Raised phosphate 
    Low phosphate 1 
    Raised bilirubin 
    Raised calcium 
    Raised glucose 
    Low CO2 2 
    Raised lactate dehydrogenase 
    Low lactate dehydrogenase 
    Raised cholesterol 
    Low WBC count 
    Raised neutrophil count 
    Raised lymphocyte count 
    Raised eosinophil count 
    Low basophil count 
    Raised platelet count 
    Low hematocrit 
    Raised chloride 
    Cellulitic foot infection 
    Flatulence 
    Nausea 
    Loose stool 
    Panic attack 
    Headache 
Possibly drug related     
    Raised bilirubin 2 
    Raised alanine aminotransferase 
Nature of event*No. individuals
Dose level (g)
0.51.02.55.0
Unlikely to be drug related     
    Raised urea 
    Raised creatinine 
    Low total protein 
    Raised albumin 
    Raised phosphate 
    Low phosphate 1 
    Raised bilirubin 
    Raised calcium 
    Raised glucose 
    Low CO2 2 
    Raised lactate dehydrogenase 
    Low lactate dehydrogenase 
    Raised cholesterol 
    Low WBC count 
    Raised neutrophil count 
    Raised lymphocyte count 
    Raised eosinophil count 
    Low basophil count 
    Raised platelet count 
    Low hematocrit 
    Raised chloride 
    Cellulitic foot infection 
    Flatulence 
    Nausea 
    Loose stool 
    Panic attack 
    Headache 
Possibly drug related     
    Raised bilirubin 2 
    Raised alanine aminotransferase 
*

All (except where indicated) National Cancer Institute Common Toxicity Criteria grade 1.

National Cancer Institute Common Toxicity Criteria grade 2.

In one of these two individuals, event was National Cancer Institute Common Toxicity Criteria grade 2.

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