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Table 1

Hematology analysis for mice treated with vehicle alone (control), 6-TG, trans-AVTG, or cis-AVTP for two cycles as described in “Materials and Methods”

Values presented are the means ± SD (n = 3–4). PLT, platelets.

DrugDose (μmol/kg)WBC (×103 cells/μl)RBC (×106 cells/μl)PLT (×103 cells/μl)
Control  7.8 ± 1.1 9.3 ± 0.4 1167 ± 204 
6-TG 8.5 5.3 ± 1.6 8.3 ± 0.2 906 ± 140 
 21.25 3.6 ± 0.1a 8.0 ± 0.3a 1351 ± 126 
trans-AVTG 8.5 5.4 ± 1.6 8.9 ± 0.5 1054 ± 61 
 21.25 2.3 ± 1.2a 7.6 ± 1.0a 828 ± 144 
cis-AVTP 8.5 5.9 ± 2.3 9.5 ± 0.3 1160 ± 349 
 21.25 8.4 ± 1.9 9.0 ± 0.5 1257 ± 335 
DrugDose (μmol/kg)WBC (×103 cells/μl)RBC (×106 cells/μl)PLT (×103 cells/μl)
Control  7.8 ± 1.1 9.3 ± 0.4 1167 ± 204 
6-TG 8.5 5.3 ± 1.6 8.3 ± 0.2 906 ± 140 
 21.25 3.6 ± 0.1a 8.0 ± 0.3a 1351 ± 126 
trans-AVTG 8.5 5.4 ± 1.6 8.9 ± 0.5 1054 ± 61 
 21.25 2.3 ± 1.2a 7.6 ± 1.0a 828 ± 144 
cis-AVTP 8.5 5.9 ± 2.3 9.5 ± 0.3 1160 ± 349 
 21.25 8.4 ± 1.9 9.0 ± 0.5 1257 ± 335 
a

Significantly different from the corresponding control value (P < 0.05).

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