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Table 6

Estrogenicity of lignans in immature rats as measured by uterine weight

Treatment groupnRelative uterine weight (mg/100 g bw)
Control 46 ± 5a 
Control + 10% ethanol 48 ± 8a 
Diethylstilbestrol 2 μg/kg bw 164 ± 20b 
Finrozole 10 mg/kg bw 31 ± 3c 
ENL 50 mg/kg bw 47 ± 5a 
MR 50 mg/kg bw 55 ± 9a 
SECO 50 mg/kg bw 49 ± 6a 
HMR 50 mg/kg bw 49 ± 7a 
Treatment groupnRelative uterine weight (mg/100 g bw)
Control 46 ± 5a 
Control + 10% ethanol 48 ± 8a 
Diethylstilbestrol 2 μg/kg bw 164 ± 20b 
Finrozole 10 mg/kg bw 31 ± 3c 
ENL 50 mg/kg bw 47 ± 5a 
MR 50 mg/kg bw 55 ± 9a 
SECO 50 mg/kg bw 49 ± 6a 
HMR 50 mg/kg bw 49 ± 7a 
a–c

Relative weights with the different letters a, b, and c indicate statistically significant differences. (P < 0.05) between the treatment groups tested by Kruskal-Wallis (median) test followed by Mann-Whitney U test.

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