American Association for Cancer Research

Table 6

Estrogenicity of lignans in immature rats as measured by uterine weight

Treatment group	n	Relative uterine weight (mg/100 g bw)
Control	9	46 ± 5^a
Control + 10% ethanol	5	48 ± 8^a
Diethylstilbestrol 2 μg/kg bw	8	164 ± 20^b
Finrozole 10 mg/kg bw	6	31 ± 3^c
ENL 50 mg/kg bw	6	47 ± 5^a
MR 50 mg/kg bw	4	55 ± 9^a
SECO 50 mg/kg bw	6	49 ± 6^a
HMR 50 mg/kg bw	6	49 ± 7^a

Treatment group	n	Relative uterine weight (mg/100 g bw)
Control	9	46 ± 5^a
Control + 10% ethanol	5	48 ± 8^a
Diethylstilbestrol 2 μg/kg bw	8	164 ± 20^b
Finrozole 10 mg/kg bw	6	31 ± 3^c
ENL 50 mg/kg bw	6	47 ± 5^a
MR 50 mg/kg bw	4	55 ± 9^a
SECO 50 mg/kg bw	6	49 ± 6^a
HMR 50 mg/kg bw	6	49 ± 7^a

^a–c

Relative weights with the different letters ^{a, b,} and ^c indicate statistically significant differences. (P < 0.05) between the treatment groups tested by Kruskal-Wallis (median) test followed by Mann-Whitney U test.

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