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Table 5

Cox regression model for survival^a

Predictor	P	Risk ratio^b (95% CI)
Cumulative dose^c (100 mg/m²)	<0.0001	0.82 (0.74–0.90)
AAG (1.11–1.85 grams/liter)	<0.0001	1.76 (1.40–2.21)
Nb disease sites (<2 to ≥2)	0.0049	1.96 (1.23–3.12)

Predictor	P	Risk ratio^b (95% CI)
Cumulative dose^c (100 mg/m²)	<0.0001	0.82 (0.74–0.90)
AAG (1.11–1.85 grams/liter)	<0.0001	1.76 (1.40–2.21)
Nb disease sites (<2 to ≥2)	0.0049	1.96 (1.23–3.12)

^a

Death occurred in 70.5% of the patients (127 of 180 patients).

^b

Risk ratio for change of covariates given in brackets.

^c

Time-dependent covariate.