American Association for Cancer Research

Table 3

Logistic regression models for adverse events at cycle 1

End point^a	Predictor	P	Odds ratio^b (95% CI)
TOX	AUC (4.2–6.5 μg·h/ml)	0.0021	1.81 (1.24–2.64)
TOX1	AUC (4.2–6.5 μg·h/ml)	0.0005	2.37 (1.46–3.87)
	AAG (1.11–1.85 grams/liter)	0.0505	0.47 (0.22–1.00)

End point^a	Predictor	P	Odds ratio^b (95% CI)
TOX	AUC (4.2–6.5 μg·h/ml)	0.0021	1.81 (1.24–2.64)
TOX1	AUC (4.2–6.5 μg·h/ml)	0.0005	2.37 (1.46–3.87)
	AAG (1.11–1.85 grams/liter)	0.0505	0.47 (0.22–1.00)

See Table 2 for definition of end points.

Odds ratio for covariate change from 25^th to 75^th percentiles for AUC and AAG.