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Table 2

Skp2 expression in relation to age, clinical stage, histological type, and histological grade in ovarian adenocarcinomas

NSkp2-positive expression (%)a
Adenocarcinoma 91 43 (47.3) 
 Age (yr)   
  <50 41 16 (39.0) 
  >51 50 27 (54.0) 
 Clinical stage   
  Stage I 34 10 (29.4)b 
  Stage II/III/IV 57 33 (57.9)b 
 Histological type   
  Serous 39 23 (59.0)c 
  Mucinous 19 5 (26.3)c 
  Endometrioid 18 8 (44.4) 
  Clear cell 15 7 (46.7) 
 Histological grade   
  Grade 1 56 27 (48.2) 
  Grade 2/3 35 16 (45.7) 
NSkp2-positive expression (%)a
Adenocarcinoma 91 43 (47.3) 
 Age (yr)   
  <50 41 16 (39.0) 
  >51 50 27 (54.0) 
 Clinical stage   
  Stage I 34 10 (29.4)b 
  Stage II/III/IV 57 33 (57.9)b 
 Histological type   
  Serous 39 23 (59.0)c 
  Mucinous 19 5 (26.3)c 
  Endometrioid 18 8 (44.4) 
  Clear cell 15 7 (46.7) 
 Histological grade   
  Grade 1 56 27 (48.2) 
  Grade 2/3 35 16 (45.7) 
a

Skp2 expression positive, more than 5% positive tumor cell staining including partial positive and diffuse positive.

b

Significant; stage I versus stage II/III/IV: P = 0.010 (Fisher’s exact test).

c

Significant; serous versus mucinous adenocarcinoma: P = 0.019 (Fisher’s exact test).

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