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Table 1

Total number of lesions, response assessments, response ranks, and response categories in six sample patients, analyzing groupings of five lesions with RECIST criteria

Patient 4 has response assessments falling into three different categories, but the proportion falling in RANK1 is very high (92%); in contrast, patient 3 has response assessments falling into fewer (two) categories, but RANK1 is only 60%. A large proportion of lesion combinations (40%) will fall into a second response category. Therefore, patient 3 is nearly evenly split between two response categories, whereas patient 4’s response almost always (92%) falls into one category (but with the potential for two other response categories 8% of the time).

Patient no.Total no. of lesionsNo. of groupingsResponse assessmentResponse rankNo. of response categories
CRPRSDPD123
21 21 
16 4368 3697 671 0.85 0.15 
10 252 100 152 0.6 0.4 
10 252 232 19 0.92 0.08 0.004 
12 792 31 761 0.96 0.04 
15 3003 3003 
Patient no.Total no. of lesionsNo. of groupingsResponse assessmentResponse rankNo. of response categories
CRPRSDPD123
21 21 
16 4368 3697 671 0.85 0.15 
10 252 100 152 0.6 0.4 
10 252 232 19 0.92 0.08 0.004 
12 792 31 761 0.96 0.04 
15 3003 3003 
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