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Table 2

Toxicity for all cycles (worst grade)a

1234(% Grades 3–4)
Myalgias 13 (6) 40.6 
Ataxiab 9.3 
Headache  
Fatigue 17 6.3 
Urinary frequency 6.3 
Dyspnea 15.6 
Anemia 6.3 
Leg weakness 3.1 
Allergic reaction 3.1 
GI (N/V)c  
Anorexia 3.1 
Edema/weight gain 3.1 
1234(% Grades 3–4)
Myalgias 13 (6) 40.6 
Ataxiab 9.3 
Headache  
Fatigue 17 6.3 
Urinary frequency 6.3 
Dyspnea 15.6 
Anemia 6.3 
Leg weakness 3.1 
Allergic reaction 3.1 
GI (N/V)c  
Anorexia 3.1 
Edema/weight gain 3.1 
a

Six of the 13 patients had grade 3 myalgias after three or greater cycles.

b

Reported ataxia was noted in two, three, and seven cycles.

c

GI (N/V), Gastrointestinal (Nausea/Vomiting).

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