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Table 3

Association of ET-1 expression with clinicopathological variables in primary breast cancer patients

Clinicopathological variablesET-1 status n positive/total (%)P                  a
pT stage   
 pT1 22/68 (32.4) 0.036b 
 pT2 26/52 (50.0)  
 pT3 5/11 (45.5)  
 pT4 16/29 (55.2)  
Histologic grading   
 I–II 31/99 (31.3) <0.0001 
 III 37/60 (61.7)  
Lymphovascular invasion   
 No 48/122 (39.3) NSc; 0.030 
 Yes 21/38 (55.3)  
Distant metastasis   
 No 42/114 (36.8) 0.012 
 Yes 27/46 (58.7)  
Clinicopathological variablesET-1 status n positive/total (%)P                  a
pT stage   
 pT1 22/68 (32.4) 0.036b 
 pT2 26/52 (50.0)  
 pT3 5/11 (45.5)  
 pT4 16/29 (55.2)  
Histologic grading   
 I–II 31/99 (31.3) <0.0001 
 III 37/60 (61.7)  
Lymphovascular invasion   
 No 48/122 (39.3) NSc; 0.030 
 Yes 21/38 (55.3)  
Distant metastasis   
 No 42/114 (36.8) 0.012 
 Yes 27/46 (58.7)  
a

χ2 test.

b

χ2 test for linear trend.

c

NS, not significant.

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