Association of increased ETAR expression with clinicopathological variables in primary breast cancer patients
| Clinicopathological variables . | ETAR staining n positive/total (%) . | P a . |
|---|---|---|
| PT stage | ||
| ≤pT2 | 53/120 (44.2) | NSb; 0.642 |
| ≥pT3 | 21/39 (53.9) | |
| Lymph node status | ||
| Negative | 35/87 (40.2) | NS; 0.137 |
| Positive | 36/69 (52.2) | |
| Histologic grading | ||
| I–II | 38/98 (38.8) | 0.009 |
| III | 36/60 (60.0) | |
| ER status | ||
| Positive | 52/96 (54.2) | 0.038 |
| Negative | 21/57 (36.8) | |
| PR status | ||
| Positive | 36/73 (49.3) | NS; 0.760 |
| Negative | 37/79 (46.8) | |
| Her-2/neu status | ||
| Negative | 63/143 (44.0) | 0.003 |
| Positive | 10/11 (90.9) | |
| MIB-1-labeling index | ||
| ≤20% | 45/99 (45.5) | NS; 0.590 |
| >20% | 27/54 (50.0) | |
| Lymphovascular invasion | ||
| No | 51/122 (41.8) | 0.030 |
| Yes | 23/37 (62.2) | |
| Local recurrence | ||
| No | 60/138 (43.5) | 0.047 |
| Yes | 14/21 (66.7) | |
| Distant metastasis | ||
| No | 46/114 (40.3) | 0.013 |
| Yes | 28/45 (62.2) | |
| 5-yr DFST | ||
| Yes | 36/94 (38.3) | 0.030 |
| No | 24/41 (58.5) |
| Clinicopathological variables . | ETAR staining n positive/total (%) . | P a . |
|---|---|---|
| PT stage | ||
| ≤pT2 | 53/120 (44.2) | NSb; 0.642 |
| ≥pT3 | 21/39 (53.9) | |
| Lymph node status | ||
| Negative | 35/87 (40.2) | NS; 0.137 |
| Positive | 36/69 (52.2) | |
| Histologic grading | ||
| I–II | 38/98 (38.8) | 0.009 |
| III | 36/60 (60.0) | |
| ER status | ||
| Positive | 52/96 (54.2) | 0.038 |
| Negative | 21/57 (36.8) | |
| PR status | ||
| Positive | 36/73 (49.3) | NS; 0.760 |
| Negative | 37/79 (46.8) | |
| Her-2/neu status | ||
| Negative | 63/143 (44.0) | 0.003 |
| Positive | 10/11 (90.9) | |
| MIB-1-labeling index | ||
| ≤20% | 45/99 (45.5) | NS; 0.590 |
| >20% | 27/54 (50.0) | |
| Lymphovascular invasion | ||
| No | 51/122 (41.8) | 0.030 |
| Yes | 23/37 (62.2) | |
| Local recurrence | ||
| No | 60/138 (43.5) | 0.047 |
| Yes | 14/21 (66.7) | |
| Distant metastasis | ||
| No | 46/114 (40.3) | 0.013 |
| Yes | 28/45 (62.2) | |
| 5-yr DFST | ||
| Yes | 36/94 (38.3) | 0.030 |
| No | 24/41 (58.5) |