Editors of the AACR journals reviewed recently published content to identify hot topics across the entire portfolio. This publication focuses on tumor heterogeniety and highlights articles based on a number of key metrics, such as usage and citations. We hope that you enjoy this complimentary cross-journal collection.
- Multi-omic analysis of subtype evolution and heterogeneity in high-grade serous ovarian carcinoma
Ludwig Geistlinger…Levi Waldron Cancer Research August 2020. - Tumor Microenvironment Is Critical for the Maintenance of Cellular States Found in Primary Glioblastomas
Allison R. Pine…Howard A. Fine Cancer Discovery April 2020. - Cytotoxic Therapy–Induced Effects on Both Hematopoietic and Marrow Stromal Cells Promotes Therapy-Related Myeloid Neoplasms
Angela Stoddart…Michelle M. Le Beau Blood Cancer Discovery April 2020. - A TGFβ-Dependent Stromal Subset Underlies Immune Checkpoint Inhibitor Efficacy in DNA Mismatch Repair–Deficient/Microsatellite Instability-High Colorectal Cancer
Eisei Endo…Koji Kono Molecular Cancer Research June 2020. - The Outcome of Ex Vivo TIL Expansion Is Highly Influenced by Spatial Heterogeneity of the Tumor T-Cell Repertoire and Differences in Intrinsic In Vitro Growth Capacity between T-Cell Clones
Isabel C. Poschke...Rienk Offringa Clinical Cancer Research April 2020. - Single-Cell Analysis Reveals Fibroblast Clusters Linked to Immunotherapy Resistance in Cancer
Yann Kieffer...Fatima Mechta-Grigoriou Cancer Discovery May 2020. - Proteogenomics Uncovers a Vast Repertoire of Shared Tumor-Specific Antigens in Ovarian Cancer
Qingchuan Zhao...Claude Perreault Cancer Immunology Research February 2020. - Mutational Landscape and Patterns of Clonal Evolution in Relapsed Pediatric Acute Lymphoblastic Leukemia
Esmé Waanders...Charles G. Mullighan Blood Cancer Discovery January 2020.
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