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Journal Articles

Colorectal Cancer Develops Inherent Radiosensitivity That Can Be Predicted Using Patient-Derived Organoids

Kuo-Shun Hsu, Mohammad Adileh, Maria Laura Martin, Vladimir Makarov, Jiapeng Chen, Chao Wu, Sahra Bodo, Stefan Klingler, Charles-Etienne Gabriel Sauvé, Bryan C. Szeglin, J. Joshua Smith, Zvi Fuks, Nadeem Riaz, Timothy A. Chan, Makoto Nishimura, Philip B. Paty, Richard Kolesnick

Cancer Res (2022) 82 (12): 2298–2312.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-4128

Published: 15 June 2022

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Includes: Supplementary data

Journal Articles

NR2F1 Is a Barrier to Dissemination of Early-Stage Breast Cancer Cells

Carolina Rodriguez-Tirado, Nupura Kale, Maria J. Carlini, Nitisha Shrivastava, Alcina A. Rodrigues, Bassem D. Khalil, Jose Javier Bravo-Cordero, Yan Hong, Melissa Alexander, Jiayi Ji, Fariba Behbod, Maria Soledad Sosa

Cancer Res (2022) 82 (12): 2313–2326.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-4145

Published: 15 June 2022

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Includes: Multimedia, Supplementary data

Journal Articles

The Oncogenic PI3K-Induced Transcriptomic Landscape Reveals Key Functions in Splicing and Gene Expression Regulation

Cancer Res (2022) 82 (12): 2269–2280.

DOI: https://doi.org/10.1158/0008-5472.CAN-22-0446

Published: 15 June 2022

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Includes: Supplementary data

Journal Articles

Chemotherapy Coupled to Macrophage Inhibition Induces T-cell and B-cell Infiltration and Durable Regression in Triple-Negative Breast Cancer

Cancer Res (2022) 82 (12): 2281–2297.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-3714

Published: 15 June 2022

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Includes: Supplementary data

Journal Articles

Functional Genomic Analysis of CDK4 and CDK6 Gene Dependency across Human Cancer Cell Lines

Zhouwei Zhang, Lior Golomb, Matthew Meyerson

Cancer Res (2022) 82 (11): 2171–2184.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-2428

Published: 06 June 2022

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Includes: Supplementary data

Journal Articles

Phosphorylation and Stabilization of PD-L1 by CK2 Suppresses Dendritic Cell Function

Xixi Zhao, Yongkun Wei, Yu-Yi Chu, Yintao Li, Jung-Mao Hsu, Zhou Jiang, Chunxiao Liu, Jennifer L. Hsu, Wei-Chao Chang, Riyao Yang, Li-Chuan Chan, Jingkun Qu, Shuqun Zhang, Haoqiang Ying, Dihua Yu, Mien-Chie Hung

Cancer Res (2022) 82 (11): 2185–2195.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-2300

Published: 06 June 2022

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Includes: Supplementary data

Journal Articles

Tumor Intrinsic PD-L1 Promotes DNA Repair in Distinct Cancers and Suppresses PARP Inhibitor–Induced Synthetic Lethality

Cancer Res (2022) 82 (11): 2156–2170.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-2076

Published: 06 June 2022

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Journal Articles

HSP90 Mediates IFNγ-Induced Adaptive Resistance to Anti-PD-1 Immunotherapy

Ke Liu, Jun Huang, Jiao Liu, Changfeng Li, Guido Kroemer, Daolin Tang, Rui Kang

Cancer Res (2022) 82 (10): 2003–2018.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-3917

Published: 16 May 2022

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Includes: Supplementary data

Journal Articles

Thymosin α-1 Reverses M2 Polarization of Tumor-Associated Macrophages during Efferocytosis

Yi-ting Wei, Xu-ru Wang, Chunguang Yan, Fang Huang, Yunpeng Zhang, Xueming Liu, Zhi-fa Wen, Xiao-tong Sun, Yue Zhang, Yong-qiang Chen, Rong Gao, Ning Pan, Li-xin Wang

Cancer Res (2022) 82 (10): 1991–2002.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-4260

Published: 16 May 2022

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Includes: Supplementary data

Journal Articles

Liver Colonization by Colorectal Cancer Metastases Requires YAP-Controlled Plasticity at the Micrometastatic Stage

Maria C. Heinz, Niek A. Peters, Koen C. Oost, Rik G.H. Lindeboom, Lisa van Voorthuijsen, Arianna Fumagalli, Mirjam C. van der Net, Gustavo de Medeiros, Joris H. Hageman, Ingrid Verlaan-Klink, Inne H.M. Borel Rinkes, Prisca Liberali, Martijn Gloerich, Jacco van Rheenen, Michiel Vermeulen, Onno Kranenburg, Hugo J.G. Snippert

Cancer Res (2022) 82 (10): 1953–1968.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-0933

Published: 16 May 2022

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Includes: Multimedia, Supplementary data

Journal Articles

Carbon Monoxide Activates PERK-Regulated Autophagy to Induce Immunometabolic Reprogramming and Boost Antitumor T-cell Function

Cancer Res (2022) 82 (10): 1969–1990.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-3155

Published: 16 May 2022

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Includes: Supplementary data

Journal Articles

Secretion of IL1 by Dedifferentiated Melanoma Cells Inhibits JAK1-STAT3–Driven Actomyosin Contractility of Lymph Node Fibroblastic Reticular Cells

Christopher Rovera, Ilona Berestjuk, Margaux Lecacheur, Cassandre Tavernier, Serena Diazzi, Sabrina Pisano, Marie Irondelle, Aude Mallavialle, Jean Albrengues, Cédric Gaggioli, Christophe A. Girard, Thierry Passeron, Marcel Deckert, Sophie Tartare-Deckert, Virginie Prod'homme

Cancer Res (2022) 82 (9): 1774–1788.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-0501

Published: 03 May 2022

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Includes: Supplementary data

Journal Articles

JNK Signaling Promotes Bladder Cancer Immune Escape by Regulating METTL3-Mediated m⁶A Modification of PD-L1 mRNA

Zegui Ni, Pengli Sun, Jin Zheng, Mingqing Wu, Congcong Yang, Maosheng Cheng, Mingwei Yin, Chengying Cui, Guangxian Wang, Lin Yuan, Qian Gao, Yang Li

Cancer Res (2022) 82 (9): 1789–1802.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-1323

Published: 03 May 2022

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Includes: Supplementary data

Journal Articles

Concurrent Activation of Kras and Canonical Wnt Signaling Induces Premalignant Lesions That Progress to Extrahepatic Biliary Cancer in Mice

Cancer Res (2022) 82 (9): 1803–1817.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-2176

Published: 03 May 2022

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Includes: Supplementary data

Journal Articles

Noncanonical Function of AGO2 Augments T-cell Receptor Signaling in T-cell Prolymphocytic Leukemia

Till Braun, Johanna Stachelscheid, Nadine Bley, Sebastian Oberbeck, Moritz Otte, Tony Andreas Müller, Linus Wahnschaffe, Markus Glaß, Katharina Ommer, Marek Franitza, Birgit Gathof, Janine Altmüller, Michael Hallek, Daniel Auguin, Stefan Hüttelmaier, Alexandra Schrader, Marco Herling

Cancer Res (2022) 82 (9): 1818–1831.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-1908

Published: 03 May 2022

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Includes: Supplementary data

Journal Articles

Phosphoinositide-Binding Protein TIPE1 Promotes Alternative Activation of Macrophages and Tumor Progression via PIP3/Akt/TGFβ Axis

Yang Cheng, Fuxiang Bai, Xiaolei Ren, Renhui Sun, Xiaowei Guo, Wen Liu, Bo Wang, Yongheng Yang, Xiaolu Zhang, Yong Xu, Chunyang Li, Xiaoyun Yang, Lifen Gao, Chunhong Ma, Xueen Li, Xiaohong Liang

Cancer Res (2022) 82 (8): 1603–1616.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-0003

Published: 15 April 2022

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Includes: Supplementary data

Journal Articles

Phosphatidylserine Synthase PTDSS1 Shapes the Tumor Lipidome to Maintain Tumor-Promoting Inflammation

Cancer Res (2022) 82 (8): 1617–1632.

DOI: https://doi.org/10.1158/0008-5472.CAN-20-3870

Published: 15 April 2022

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Includes: Supplementary data

Journal Articles

Ketogenesis Attenuates KLF5-Dependent Production of CXCL12 to Overcome the Immunosuppressive Tumor Microenvironment in Colorectal Cancer

Ruozheng Wei, Yuning Zhou, Chang Li, Piotr Rychahou, Shulin Zhang, William B. Titlow, Greg Bauman, Yuanyuan Wu, Jinpeng Liu, Chi Wang, Heidi L. Weiss, B. Mark Evers, Qingding Wang

Cancer Res (2022) 82 (8): 1575–1588.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-2778

Published: 15 April 2022

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Includes: Supplementary data

Journal Articles

Combinatorial Inactivation of Tumor Suppressors Efficiently Initiates Lung Adenocarcinoma with Therapeutic Vulnerabilities

Cancer Res (2022) 82 (8): 1589–1602.

DOI: https://doi.org/10.1158/0008-5472.CAN-22-0059

Published: 15 April 2022

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Includes: Supplementary data

Journal Articles

Preclinical Development and Evaluation of Allogeneic CAR T Cells Targeting CD70 for the Treatment of Renal Cell Carcinoma

Siler H. Panowski, Surabhi Srinivasan, Nguyen Tan, Silvia K. Tacheva-Grigorova, Bryan Smith, Yvonne S.L. Mak, Hongxiu Ning, Jonathan Villanueva, Dinali Wijewarnasuriya, Shanshan Lang, Zea Melton, Adit Ghosh, Mathilde Dusseaux, Roman Galetto, Jonathan R. Heyen, Tao Sai, Thomas Van Blarcom, Javier Chaparro-Riggers, Barbra J. Sasu

Cancer Res OF1–OF15.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-2931

Published: 13 April 2022

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Includes: Supplementary data

2 3 4 5

NARROW

Colorectal Cancer Develops Inherent Radiosensitivity That Can Be Predicted Using Patient-Derived Organoids

NR2F1 Is a Barrier to Dissemination of Early-Stage Breast Cancer Cells

The Oncogenic PI3K-Induced Transcriptomic Landscape Reveals Key Functions in Splicing and Gene Expression Regulation

Chemotherapy Coupled to Macrophage Inhibition Induces T-cell and B-cell Infiltration and Durable Regression in Triple-Negative Breast Cancer

Functional Genomic Analysis of CDK4 and CDK6 Gene Dependency across Human Cancer Cell Lines

Phosphorylation and Stabilization of PD-L1 by CK2 Suppresses Dendritic Cell Function

Tumor Intrinsic PD-L1 Promotes DNA Repair in Distinct Cancers and Suppresses PARP Inhibitor–Induced Synthetic Lethality

HSP90 Mediates IFNγ-Induced Adaptive Resistance to Anti-PD-1 Immunotherapy

Thymosin α-1 Reverses M2 Polarization of Tumor-Associated Macrophages during Efferocytosis

Liver Colonization by Colorectal Cancer Metastases Requires YAP-Controlled Plasticity at the Micrometastatic Stage

Carbon Monoxide Activates PERK-Regulated Autophagy to Induce Immunometabolic Reprogramming and Boost Antitumor T-cell Function

Secretion of IL1 by Dedifferentiated Melanoma Cells Inhibits JAK1-STAT3–Driven Actomyosin Contractility of Lymph Node Fibroblastic Reticular Cells

JNK Signaling Promotes Bladder Cancer Immune Escape by Regulating METTL3-Mediated m⁶A Modification of PD-L1 mRNA

Concurrent Activation of Kras and Canonical Wnt Signaling Induces Premalignant Lesions That Progress to Extrahepatic Biliary Cancer in Mice

Noncanonical Function of AGO2 Augments T-cell Receptor Signaling in T-cell Prolymphocytic Leukemia

Phosphoinositide-Binding Protein TIPE1 Promotes Alternative Activation of Macrophages and Tumor Progression via PIP3/Akt/TGFβ Axis

Phosphatidylserine Synthase PTDSS1 Shapes the Tumor Lipidome to Maintain Tumor-Promoting Inflammation

Ketogenesis Attenuates KLF5-Dependent Production of CXCL12 to Overcome the Immunosuppressive Tumor Microenvironment in Colorectal Cancer

Combinatorial Inactivation of Tumor Suppressors Efficiently Initiates Lung Adenocarcinoma with Therapeutic Vulnerabilities

Preclinical Development and Evaluation of Allogeneic CAR T Cells Targeting CD70 for the Treatment of Renal Cell Carcinoma

AACR Journals

AACR Journals

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