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Journal Articles

Abstract PO-057: Breast cancer cell metabolism: Effect of beta-hydroxybutyrate on glucose deprived breast cancer cells

Rylee Maldonado, Chloe Adrienna Talana, Kahealani Uehara, Michael Weichhaus
Journal: Cancer Research
Cancer Res (2020) 80 (23_Supplement): PO-057.
DOI: https://doi.org/10.1158/1538-7445.EPIMETAB20-PO-057
Published: 02 December 2020
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Journal Articles

Abstract PO-056: Role of the metabolite N-acetylaspartate in breast cancer progression

Akhila Balasubramanian, Weijie Zhang, Franklin Gu, Chandra Ambati, Nagireddy Putluri, Xiang Zhang, Aryan Namboodiri, Stefan Ambs, Arun Sreekumar
Journal: Cancer Research
Cancer Res (2020) 80 (23_Supplement): PO-056.
DOI: https://doi.org/10.1158/1538-7445.EPIMETAB20-PO-056
Published: 02 December 2020
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Abstract PO-015: Hypermethylated genes in leiomyosarcoma can be targeted through guadecitabine treatment

Nesrin Hasan, Cynthia De Carvalho Fischer, Anup Sharma, Nita Ahuja
Journal: Cancer Research
Cancer Res (2020) 80 (23_Supplement): PO-015.
DOI: https://doi.org/10.1158/1538-7445.EPIMETAB20-PO-015
Published: 02 December 2020
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Abstract PO-014: DNA methyltransferases drive gastric cancer growth and present a therapy target for gastric cancer

Anne Huber, Christine Dijkstra, Matthias Ernst, Moritz Eissmann
Journal: Cancer Research
Cancer Res (2020) 80 (23_Supplement): PO-014.
DOI: https://doi.org/10.1158/1538-7445.EPIMETAB20-PO-014
Published: 02 December 2020
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Journal Articles

Abstract PO-007: The Class I/IV HDAC Inhibitor Mocetinostat Augments Anti-Tumor Immune Responses in Melanoma Patients

David M. Woods, Andressa S. Laino, Melinda Vassallo, Jeffrey Weber
Journal: Cancer Research
Cancer Res (2020) 80 (23_Supplement): PO-007.
DOI: https://doi.org/10.1158/1538-7445.EPIMETAB20-PO-007
Published: 02 December 2020
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Journal Articles

Abstract PR09: Developing metabolic intervention strategies to reprogram neuroblastoma epigenome and overcome tumor resistance to differentiation therapy

Haowen Jiang, Yang Li, Michela Yip, Joshua Gruber, Albert Li, Jiangbin Ye
Journal: Cancer Research
Cancer Res (2020) 80 (23_Supplement): PR09.
DOI: https://doi.org/10.1158/1538-7445.EPIMETAB20-PR09
Published: 02 December 2020
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Journal Articles

Abstract PR08: IL4 signaling increases acetyl-CoA metabolism and histone acetylation to promote breast cancer metastasis

Demond Williams, Chilesi Uririr, Barbara Fingleton
Journal: Cancer Research
Cancer Res (2020) 80 (23_Supplement): PR08.
DOI: https://doi.org/10.1158/1538-7445.EPIMETAB20-PR08
Published: 02 December 2020
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Journal Articles

Abstract PO-051: Metabolic alterations reveal epigenetic vulnerabilities in breast cancer

Genevieve Deblois
Journal: Cancer Research
Cancer Res (2020) 80 (23_Supplement): PO-051.
DOI: https://doi.org/10.1158/1538-7445.EPIMETAB20-PO-051
Published: 02 December 2020
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Journal Articles

Abstract PO-048: MicroRNA-10b is a regulator of cellular viability and proliferation in fibrolamellar carcinoma

Adam Francisco, Andrew Massa, Matt Kanke, Praveen Sethupathy
Journal: Cancer Research
Cancer Res (2020) 80 (23_Supplement): PO-048.
DOI: https://doi.org/10.1158/1538-7445.EPIMETAB20-PO-048
Published: 02 December 2020
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Journal Articles

Abstract PO-009: Disrupting chromatin architecture: The NuRD subunit and ATPase CHD4 as a new therapeutic target in pediatric sarcoma

Joana G. Marques, Berkley Gryder, Blaz Pavlovic, Yeonjoo Chung, Quy Ngo, Marco Wachtel, Javed Khan, Beat Schäfer
Journal: Cancer Research
Cancer Res (2020) 80 (23_Supplement): PO-009.
DOI: https://doi.org/10.1158/1538-7445.EPIMETAB20-PO-009
Published: 02 December 2020
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Journal Articles

Abstract PO-008: Bithioether Stapled Peptides as Allosteric Inhibitors of PRC2 function

Gan Zhang, Adam Herskovits, Nissim Levy, Guillermo Gerona-Navarro
Journal: Cancer Research
Cancer Res (2020) 80 (23_Supplement): PO-008.
DOI: https://doi.org/10.1158/1538-7445.EPIMETAB20-PO-008
Published: 02 December 2020
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Abstract PO-003: Adaptation of colorectal cancer cells to the brain microenvironment: The role of IRS2

Inbal Greenberg, Anat Klein, Rachel Grossman, Ethan Sokol, Eilam Yeini, Paula Ofek, Ronit Satchi-Fainaro, Hadas Reuveni, Tami Rubinek, Ido Wolf
Journal: Cancer Research
Cancer Res (2020) 80 (23_Supplement): PO-003.
DOI: https://doi.org/10.1158/1538-7445.EPIMETAB20-PO-003
Published: 02 December 2020
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Journal Articles

Abstract PO-041: Genome-wide CRISPR/Cas9 screen reveals mitochondrial gene mutation as a driver for drug resistance in Ewing sarcoma

Jack P. Tokarsky, Jesse Crow, Lillian Guenther, Emily Theisen, Kimberly Stegmaier, Stephen Lessnick
Journal: Cancer Research
Cancer Res (2020) 80 (23_Supplement): PO-041.
DOI: https://doi.org/10.1158/1538-7445.EPIMETAB20-PO-041
Published: 02 December 2020
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Journal Articles

Abstract PO-040: The role of mTOR in epigenetic regulation in cancer

HaEun Kim, David Papadopoli, Ivan Topisirovic
Journal: Cancer Research
Cancer Res (2020) 80 (23_Supplement): PO-040.
DOI: https://doi.org/10.1158/1538-7445.EPIMETAB20-PO-040
Published: 02 December 2020
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Journal Articles

Abstract PO-020: Targeting metabolism to improve response to immune-checkpoint inhibition in melanoma

Jiske F. Tiersma, Bernard Evers, Barbara M. Bakker, Steven de Jong, Mathilde Jalving
Journal: Cancer Research
Cancer Res (2020) 80 (23_Supplement): PO-020.
DOI: https://doi.org/10.1158/1538-7445.EPIMETAB20-PO-020
Published: 02 December 2020
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Journal Articles

Abstract PO-019: DNA methylation status in a promoter region of the K-RAS gene in patients with Colorectal Cancer

Jehison Alirio Herrera-Pulido, Orlando Ricaurte-Guerrero, Jinneth Acosta-Forero, Pablo Moreno-Acosta, María Carolina Sanabria-Salas, Humberto Arboleda-Granados, Gustavo Hernández, Martha Lucía Serrano-López
Journal: Cancer Research
Cancer Res (2020) 80 (23_Supplement): PO-019.
DOI: https://doi.org/10.1158/1538-7445.EPIMETAB20-PO-019
Published: 02 December 2020
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Journal Articles

Abstract PO-005: Tet2 inactivation enhances the anti-tumor efficiency of tumor-infiltrating lymphocytes (TILs)

Minjung Lee, Jiangfang Li, Shaohai Fang, Wei Han, Margarita Moczygemba, Yubin Zhou, Jia Li, Deqiang Sun, Yun Huang
Journal: Cancer Research
Cancer Res (2020) 80 (23_Supplement): PO-005.
DOI: https://doi.org/10.1158/1538-7445.EPIMETAB20-PO-005
Published: 02 December 2020
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Journal Articles

Abstract PO-001: xCT expression alters the epigenome and induces genomic instability

Dalton Hill, Jamshedur Rahman, Christien Kluwe, Pierre P. Massion
Journal: Cancer Research
Cancer Res (2020) 80 (23_Supplement): PO-001.
DOI: https://doi.org/10.1158/1538-7445.EPIMETAB20-PO-001
Published: 02 December 2020
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Journal Articles

Abstract PR03: Metabolic control of Polycomb Repressive Complex 2 in Lung Disease and Lung Cancer

Mojtaba Bakhtiari, Aria L. Byrd, Fan Chen, Alexsandr Lukyanchuk, Tanner J. DuCote, Christine Fillmore Brainson
Journal: Cancer Research
Cancer Res (2020) 80 (23_Supplement): PR03.
DOI: https://doi.org/10.1158/1538-7445.EPIMETAB20-PR03
Published: 02 December 2020
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Journal Articles

Abstract PR02: Integrated metabolic and epigenomic reprograming by H3K27M mutations in diffuse intrinsic pontine gliomas

Chan Chung, Stefan Sweha, Drew Pratt, Benita Tamrazi, Pooja Panwalkar, Adam Banda, Jill Bayliss, Debra Hawes, Fusheng Yang, Ho-Joon Lee, Mengrou Shan, Marcin Cieslik, Tingting Qin, Christian Werner, Daniel Wahl, Costas Lyssiotis, Viveka Nand Yadav, Carl Koschmann, Arul Chinnaiyan, Stefan Blüml, Alexander Judkins, Sriram Venneti
Journal: Cancer Research
Cancer Res (2020) 80 (23_Supplement): PR02.
DOI: https://doi.org/10.1158/1538-7445.EPIMETAB20-PR02
Published: 02 December 2020
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