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Poster Presentations - Prognostic Biomarkers
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Journal Articles

Abstract 508: Clinical significance of a negative elongation factor-E (NELF-E) single nucleotide polymorphism in hepatocellular carcinoma (HCC)

Ryan Lamm, Anna Barry-Wolbers, Kai Zhang, Keyur Patel, Hien T. Dang
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 508.
DOI: https://doi.org/10.1158/1538-7445.AM2022-508
Published: 15 June 2022
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Journal Articles

Abstract 526: Novel methylation-based, tissue-free ctDNA assay accurately quantifies longitudinal tumor burden changes for precision treatment monitoring

Patrick Peiyong Ye, Robb Viens, Xavier Bower, Shan Riku, David Tsao, Oguzhan Atay
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 526.
DOI: https://doi.org/10.1158/1538-7445.AM2022-526
Published: 15 June 2022
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Journal Articles

Abstract 527: A streamlined workflow for liquid biopsy extraction and highplex digital PCR analysis using the Maxwell® RSC system and 6-color Crystal Digital PCR™

Cécile Jovelet, Myrtille Remy, Mylene Menanteau, Doug White, Douglas Horejsh, Allison Mallory
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 527.
DOI: https://doi.org/10.1158/1538-7445.AM2022-527
Published: 15 June 2022
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Journal Articles

Abstract 528: Automated liquid biopsy pan-cancer genomic profiling panel demonstrates utility for screening of targeted biomarkers

Lauren Frady, Desiree Unselt, John Pufky, Fernando Torres, Jennifer Sims, Jennifer Mason
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 528.
DOI: https://doi.org/10.1158/1538-7445.AM2022-528
Published: 15 June 2022
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Journal Articles

Abstract 520: MYB exhibits racially disparate overexpression and clinicopathologic association in prostate cancer: significance as a predictor of biochemical recurrence

Mohammad Aslam Khan, Srijan Acharya, Shashi Anand, Fnu Sameeta, James E. Carter, Oliver J. Semmes, Dean A. Troyer, Seema Singh, Santanu Dasgupta, Ajay P. Singh
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 520.
DOI: https://doi.org/10.1158/1538-7445.AM2022-520
Published: 15 June 2022
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Journal Articles

Abstract 521: The role of the E3 ubiquitin ligase Parkin in clear cell renal cell carcinoma

Laura Kristin Esser, Vittorio Branchi, Farhad Shaker, Adrian Georg Simon, Carsten Stephan, Glen Kristiansen, Andreas Buness, Hubert Schorle, Marieta I. Toma
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 521.
DOI: https://doi.org/10.1158/1538-7445.AM2022-521
Published: 15 June 2022
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Journal Articles

Abstract 534: An ultrasensitive high-plex assay detecting 24 PIK3CA mutations using SAGAsafe® technology and 6-color Crystal Digital PCR™

Miguel Alcaide, Anthony M. George, Yilun Chen, Cécile Jovelet, Sahbi Ben Kilani, Lao H. Saal, Allison C. Mallory
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 534.
DOI: https://doi.org/10.1158/1538-7445.AM2022-534
Published: 15 June 2022
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Journal Articles

Abstract 535: Development of a liquid biopsy assay to longitudinally monitor changes in mutations’ allelic frequency in response to treatment with KB-0742

Suha Naffar-Abu Amara, Christina Noe, Tressa Hood, Sara Paganini, Crystal MacKenzie, Melinda A. Day, Pavan Kumar
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 535.
DOI: https://doi.org/10.1158/1538-7445.AM2022-535
Published: 15 June 2022
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Journal Articles

Abstract 518: Association of CC chemokines with breast cancer disparity

Hina Mir, Briana A. Brock, Rajeev Samant, Shailesh Singh
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 518.
DOI: https://doi.org/10.1158/1538-7445.AM2022-518
Published: 15 June 2022
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Journal Articles

Abstract 519: Clinical impact ofKRASG12, G13, Q61, K117 and A146 mutations in patients with colorectal liver metastases

Iris van 't Erve, Nina J. Wesdorp, Jamie E. Medina, Leonardo Ferreira, Alessandro Leal, Joost Huiskens, Karen Bolhuis, Jan-Hein T. van Waesberghe, Rutger-Jan Swijnenburg, Daan van den Broek, Victor E. Velculescu, Geert Kazemier, Cornelis J. Punt, Gerrit A. Meijer, Remond J. Fijneman
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 519.
DOI: https://doi.org/10.1158/1538-7445.AM2022-519
Published: 15 June 2022
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Journal Articles

Abstract 537: Development of blood TMB (bTMB) reference materials for validation of cfDNA-based targeted NGS assays that measure tumor mutational burden (TMB) in patient blood samples

Dana Ruminski Lowe, Benedicta Forson, Matthew G. Butler, Yves Konigshofer, Catherine Huang, Omoshile Clement, Russell K. Garlick, Bharathi Anekella
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 537.
DOI: https://doi.org/10.1158/1538-7445.AM2022-537
Published: 15 June 2022
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Journal Articles

Abstract 538: Cell-free whole genome sequencing for the detection of cancer in patients with germline BRCA1/2 mutations

Derek Wong, Adriana Aguilar-Mahecha, Josiane Lafleur, Clarissa Chan, Kirsten Farncombe, Maia Norman, Leslie Oldfield, Prabhjit Basra, Stephanie Pederson, Johanna Wellum, Stephenie Prokopec, Mark Basik, Raymond H. Kim, Trevor Pugh
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 538.
DOI: https://doi.org/10.1158/1538-7445.AM2022-538
Published: 15 June 2022
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Journal Articles

Abstract 540: Genome-wide circulating tumor DNA for monitoring treatment response and metastatic relapse in bladder cancer

Iver Nordentoft, Karin Birkenkamp-Demtröder, Emil Christensen, Sunil Deochand, Dillon Maloney, Danielle Afterman, Tomer Lauterman, Noah Friedman, Imane Bourzgui, Nidhi Ramaraj, Zohar Donenhirsh, Ronel Veksler, Sia Viborg, Mads Agerbæk, Jørgen Bjerggaard Jensen, Jonathan Rosenfeld, Ravi Kandasamy, Iman Tavassoly, Boris Oklander, Asaf Zviran, Lars Dyrskjøt
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 540.
DOI: https://doi.org/10.1158/1538-7445.AM2022-540
Published: 15 June 2022
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Journal Articles

Abstract 509: Tumor inflammation signature (TIS) in residual disease is associated with survival in breast cancer patients with high risk of recurrence

Marco Galvez-Nino, Miluska Castillo, Luis Bernabe, Nancy Suarez, Joselyn Sanchez, Katia Roque, Silvia Neciosup, Henry Gomez, Carlos Castaneda
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 509.
DOI: https://doi.org/10.1158/1538-7445.AM2022-509
Published: 15 June 2022
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Journal Articles

Abstract 510: Molecular subtypes related to prostate cancer disparities and disease outcome in African American and European American patients

Joakin Opeli Mori, Jason White, Balasubramanyam Karanam, Clayton Yates, Honghe Wang
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 510.
DOI: https://doi.org/10.1158/1538-7445.AM2022-510
Published: 15 June 2022
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Journal Articles

Abstract 511: Prognostic relevance of 3q amplification in squamous cell carcinoma of the lung

Fawzi Abu Rous, Rebecca Chacko, Shannon Carskadon, Shanker Kalyana-Sundaram, Pin Li, Sunny Singh, Laila Poisson, Shirish Gadgeel, Nallasivam Palanisamy
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 511.
DOI: https://doi.org/10.1158/1538-7445.AM2022-511
Published: 15 June 2022
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Journal Articles

Abstract 530: UMAP- Personalized lung cancer monitoring platform

Zahra Haider, Linda Köhn, Nicholas Karlowatz, Mikael B. Johansson, Jonas A. Nilsson
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 530.
DOI: https://doi.org/10.1158/1538-7445.AM2022-530
Published: 15 June 2022
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Journal Articles

Abstract 544: Role of an ankyrin domain protein in hepatocellular carcinoma progression

Samantha Lopez, Adithya Anilkumar, Kyle Doxtater, Sudhir Kotnala, Neeraj Chauhan, Murali Yallapu, Meena Jaggi, Subhash Chauhan, Manish Tripathi
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 544.
DOI: https://doi.org/10.1158/1538-7445.AM2022-544
Published: 15 June 2022
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Journal Articles

Abstract 514: Correlation of sTNFR2 elevation and disease progression in cutaneous T cell lymphomas

Amanda Lee, Youn Kim, Michael Khodadoust, Denise L. Faustman
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 514.
DOI: https://doi.org/10.1158/1538-7445.AM2022-514
Published: 15 June 2022
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Journal Articles

Abstract 529: SNAQ-SEQ™: Use of synthetic internal standards in conjunction with poisson exact test to call variants in contrived circulating tumor DNA specimens

James C. Willey, Erin Crawford, Daniel J. Craig, Joshua Xu, Nathan Haseley, Jennifer Lococo, Tom Morrison
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 529.
DOI: https://doi.org/10.1158/1538-7445.AM2022-529
Published: 15 June 2022
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