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Journal Articles

c-MYC Drives Breast Cancer Metastasis to the Brain, but Promotes Synthetic Lethality with TRAIL

Ho Yeon Lee, Junghwa Cha, Seon Kyu Kim, Jun Hyung Park, Ki Hoon Song, Pilnam Kim, Mi-Young Kim

Mol Cancer Res (2019) 17 (2): 544–554.

DOI: https://doi.org/10.1158/1541-7786.MCR-18-0630

Published: 01 February 2019

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Includes: Supplementary data

Journal Articles

DNA Damage, Liver Injury, and Tumorigenesis: Consequences of DDX3X Loss

Chieh-Hsiang Chan, Chun-Ming Chen, Yan-Hwa Wu Lee, Li-Ru You

Mol Cancer Res (2019) 17 (2): 555–566.

DOI: https://doi.org/10.1158/1541-7786.MCR-18-0551

Published: 01 February 2019

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Includes: Supplementary data

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RNA-Binding Protein HuR Regulates Both Mutant and Wild-Type IDH1 in IDH1-Mutated Cancer

Mahsa Zarei, Shruti Lal, Ali Vaziri-Gohar, Kevin O'Hayer, Venugopal Gunda, Pankaj K. Singh, Jonathan R. Brody, Jordan M. Winter

Mol Cancer Res (2019) 17 (2): 508–520.

DOI: https://doi.org/10.1158/1541-7786.MCR-18-0557

Published: 01 February 2019

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Includes: Supplementary data

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CCR2 Chemokine Receptors Enhance Growth and Cell-Cycle Progression of Breast Cancer Cells through SRC and PKC Activation

Min Yao, Wei Fang, Curtis Smart, Qingting Hu, Shixia Huang, Nehemiah Alvarez, Patrick Fields, Nikki Cheng

Mol Cancer Res (2019) 17 (2): 604–617.

DOI: https://doi.org/10.1158/1541-7786.MCR-18-0750

Published: 01 February 2019

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Includes: Supplementary data

Journal Articles

PTPN11 Plays Oncogenic Roles and Is a Therapeutic Target for BRAF Wild-Type Melanomas

Kristen S. Hill, Evan R. Roberts, Xue Wang, Ellen Marin, Taeeun D. Park, Sorany Son, Yuan Ren, Bin Fang, Sean Yoder, Sungjune Kim, Lixin Wan, Amod A. Sarnaik, John M. Koomen, Jane L. Messina, Jamie K. Teer, Youngchul Kim, Jie Wu, Charles E. Chalfant, Minjung Kim

Mol Cancer Res (2019) 17 (2): 583–593.

DOI: https://doi.org/10.1158/1541-7786.MCR-18-0777

Published: 01 February 2019

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Includes: Supplementary data

Journal Articles

Modulation of Mutant Kras^G12D-Driven Lung Tumorigenesis In Vivo by Gain or Loss of PCDH7 Function

Xiaorong Zhou, Mahesh S. Padanad, Bret M. Evers, Bethany Smith, Nicole Novaresi, Shruthy Suresh, James A. Richardson, Emily Stein, Jingfei Zhu, Robert E. Hammer, Kathryn A. O'Donnell

Mol Cancer Res (2019) 17 (2): 594–603.

DOI: https://doi.org/10.1158/1541-7786.MCR-18-0739

Published: 01 February 2019

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Includes: Supplementary data

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Sleeping Beauty Screen Identifies RREB1 and Other Genetic Drivers in Human B-cell Lymphoma

Eric P. Rahrmann, Natalie K. Wolf, George M. Otto, Lynn Heltemes-Harris, Laura B. Ramsey, Jingmin Shu, Rebecca S. LaRue, Michael A. Linden, Susan K. Rathe, Timothy K. Starr, Michael A. Farrar, Branden S. Moriarity, David A. Largaespada

Mol Cancer Res (2019) 17 (2): 567–582.

DOI: https://doi.org/10.1158/1541-7786.MCR-18-0582

Published: 01 February 2019

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Includes: Supplementary data

Journal Articles

The FGFR1 V561M Gatekeeper Mutation Drives AZD4547 Resistance through STAT3 Activation and EMT

Molly R. Ryan, Christal D. Sohl, BeiBei Luo, Karen S. Anderson

Mol Cancer Res (2019) 17 (2): 532–543.

DOI: https://doi.org/10.1158/1541-7786.MCR-18-0429

Published: 01 February 2019

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Includes: Supplementary data

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Oncogenic STRAP Supports Hepatocellular Carcinoma Growth by Enhancing Wnt/β-Catenin Signaling

Wenhui Wang, Shan Li, Pengyu Liu, Kostandinos Sideras, Harmen J.G. van de Werken, Marieke van der Heide, Wanlu Cao, Marla Lavrijsen, Maikel P. Peppelenbosch, Marco Bruno, Qiuwei Pan, Ron Smits

Mol Cancer Res (2019) 17 (2): 521–531.

DOI: https://doi.org/10.1158/1541-7786.MCR-18-0054

Published: 01 February 2019

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Journal Articles

PDCD4 Is an Androgen-Repressed Tumor Suppressor that Regulates Prostate Cancer Growth and Castration Resistance

Kenji Zennami, Su Mi Choi, Ross Liao, Ying Li, Wikum Dinalankara, Luigi Marchionni, Fatema H. Rafiqi, Akira Kurozumi, Koji Hatano, Shawn E. Lupold

Mol Cancer Res (2019) 17 (2): 618–627.

DOI: https://doi.org/10.1158/1541-7786.MCR-18-0837

Published: 01 February 2019

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Mutational Landscape of Ovarian Adult Granulosa Cell Tumors from Whole Exome and Targeted TERT Promoter Sequencing

Maria Alexiadis, Simone M. Rowley, Simon Chu, Dilys T.H. Leung, Colin J.R. Stewart, Kaushalya C. Amarasinghe, Ian G. Campbell, Peter J. Fuller

Mol Cancer Res (2019) 17 (1): 177–185.

DOI: https://doi.org/10.1158/1541-7786.MCR-18-0359

Published: 02 January 2019

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Journal Articles

Hyperactivation of MAPK Signaling Is Deleterious to RAS/RAF-mutant Melanoma

Grace P. Leung, Tianshu Feng, Frederic D. Sigoillot, Felipe C. Geyer, Matthew D. Shirley, David A. Ruddy, Daniel P. Rakiec, Alyson K. Freeman, Jeffrey A. Engelman, Mariela Jaskelioff, Darrin D. Stuart

Mol Cancer Res (2019) 17 (1): 199–211.

DOI: https://doi.org/10.1158/1541-7786.MCR-18-0327

Published: 02 January 2019

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Includes: Supplementary data

Journal Articles

p53 Function Is Compromised by Inhibitor 2 of Phosphatase 2A in Sonic Hedgehog Medulloblastoma

Yun Wei, Victor Maximov, Sorana A. Morrissy, Michael D. Taylor, David C. Pallas, Anna Marie Kenney

Mol Cancer Res (2019) 17 (1): 186–198.

DOI: https://doi.org/10.1158/1541-7786.MCR-18-0485

Published: 02 January 2019

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Journal Articles

p53–Pirh2 Complex Promotes Twist1 Degradation and Inhibits EMT

Yang Yang-Hartwich, Roslyn Tedja, Cai M. Roberts, Jamie Goodner-Bingham, Carlos Cardenas, Marta Gurea, Natalia J. Sumi, Ayesha B. Alvero, Carlotta A. Glackin, Gil Mor

Mol Cancer Res (2019) 17 (1): 153–164.

DOI: https://doi.org/10.1158/1541-7786.MCR-18-0238

Published: 02 January 2019

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Includes: Supplementary data

Journal Articles

Increased Genetic Instability and Accelerated Progression of Colitis-Associated Colorectal Cancer through Intestinal Epithelium–specific Deletion of Klf4

Vincent W. Yang, Yang Liu, Julie Kim, Kenneth R. Shroyer, Agnieszka B. Bialkowska

Mol Cancer Res (2019) 17 (1): 165–176.

DOI: https://doi.org/10.1158/1541-7786.MCR-18-0399

Published: 02 January 2019

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Journal Articles

R1 Regulates Prostate Tumor Growth and Progression By Transcriptional Suppression of the E3 Ligase HUWE1 to Stabilize c-Myc

Tzu-Ping Lin, Jingjing Li, Qinlong Li, Xiangyan Li, Chunyan Liu, Ni Zeng, Jen-Ming Huang, Gina Chia-Yi Chu, Chi-Hung Lin, Haiyen E. Zhau, Leland W.K. Chung, Boyang Jason Wu, Jean C. Shih

Mol Cancer Res (2018) 16 (12): 1940–1951.

DOI: https://doi.org/10.1158/1541-7786.MCR-16-0346

Published: 03 December 2018

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Includes: Supplementary data

Journal Articles

miR-652 Promotes Tumor Proliferation and Metastasis by Targeting RORA in Endometrial Cancer

Xiaomei Sun, Samina Dongol, Chunping Qiu, Ying Xu, Chenggong Sun, Zhiwei Zhang, Xingsheng Yang, Qing Zhang, Beihua Kong

Mol Cancer Res (2018) 16 (12): 1927–1939.

DOI: https://doi.org/10.1158/1541-7786.MCR-18-0267

Published: 03 December 2018

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Journal Articles

Suppression of Breast Cancer Stem Cells and Tumor Growth by the RUNX1 Transcription Factor

Deli Hong, Andrew J. Fritz, Kristiaan H. Finstad, Mark P. Fitzgerald, Adam Weinheimer, Adam L. Viens, Jon Ramsey, Janet L. Stein, Jane B. Lian, Gary S. Stein

Mol Cancer Res (2018) 16 (12): 1952–1964.

DOI: https://doi.org/10.1158/1541-7786.MCR-18-0135

Published: 03 December 2018

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Journal Articles

miR-155 Is Downregulated in Familial Adenomatous Polyposis and Modulates WNT Signaling by Targeting AXIN1 and TCF4

Anna Prossomariti, Giulia Piazzi, Leonarda D'Angelo, Sara Miccoli, Daniela Turchetti, Chiara Alquati, Claudio Montagna, Franco Bazzoli, Luigi Ricciardiello

Mol Cancer Res (2018) 16 (12): 1965–1976.

DOI: https://doi.org/10.1158/1541-7786.MCR-18-0115

Published: 03 December 2018

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Includes: Supplementary data

Journal Articles

Tumor Suppressor Activity of Selenbp1, a Direct Nkx2-1 Target, in Lung Adenocarcinoma

Deborah R. Caswell, Chen-Hua Chuang, Rosanna K. Ma, Ian P. Winters, Eric L. Snyder, Monte M. Winslow

Mol Cancer Res (2018) 16 (11): 1737–1749.

DOI: https://doi.org/10.1158/1541-7786.MCR-18-0392

Published: 01 November 2018

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Includes: Supplementary data

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NARROW

c-MYC Drives Breast Cancer Metastasis to the Brain, but Promotes Synthetic Lethality with TRAIL

DNA Damage, Liver Injury, and Tumorigenesis: Consequences of DDX3X Loss

RNA-Binding Protein HuR Regulates Both Mutant and Wild-Type IDH1 in IDH1-Mutated Cancer

CCR2 Chemokine Receptors Enhance Growth and Cell-Cycle Progression of Breast Cancer Cells through SRC and PKC Activation

PTPN11 Plays Oncogenic Roles and Is a Therapeutic Target for BRAF Wild-Type Melanomas

Modulation of Mutant Kras^G12D-Driven Lung Tumorigenesis In Vivo by Gain or Loss of PCDH7 Function

Sleeping Beauty Screen Identifies RREB1 and Other Genetic Drivers in Human B-cell Lymphoma

The FGFR1 V561M Gatekeeper Mutation Drives AZD4547 Resistance through STAT3 Activation and EMT

Oncogenic STRAP Supports Hepatocellular Carcinoma Growth by Enhancing Wnt/β-Catenin Signaling

PDCD4 Is an Androgen-Repressed Tumor Suppressor that Regulates Prostate Cancer Growth and Castration Resistance

Mutational Landscape of Ovarian Adult Granulosa Cell Tumors from Whole Exome and Targeted TERT Promoter Sequencing

Hyperactivation of MAPK Signaling Is Deleterious to RAS/RAF-mutant Melanoma

p53 Function Is Compromised by Inhibitor 2 of Phosphatase 2A in Sonic Hedgehog Medulloblastoma

p53–Pirh2 Complex Promotes Twist1 Degradation and Inhibits EMT

Increased Genetic Instability and Accelerated Progression of Colitis-Associated Colorectal Cancer through Intestinal Epithelium–specific Deletion of Klf4

R1 Regulates Prostate Tumor Growth and Progression By Transcriptional Suppression of the E3 Ligase HUWE1 to Stabilize c-Myc

miR-652 Promotes Tumor Proliferation and Metastasis by Targeting RORA in Endometrial Cancer

Suppression of Breast Cancer Stem Cells and Tumor Growth by the RUNX1 Transcription Factor

miR-155 Is Downregulated in Familial Adenomatous Polyposis and Modulates WNT Signaling by Targeting AXIN1 and TCF4

Tumor Suppressor Activity of Selenbp1, a Direct Nkx2-1 Target, in Lung Adenocarcinoma

AACR Journals

AACR Journals

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