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Journal Articles

Abstract P3-09-08: An automated tool to determine optimal cluster numbers in single-cell RNA sequencing data identifies key prognostic subsets of T cells in breast tumors

Siyao Liu, Aatish Thennavan, J.S. Marron, Charles Perou
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-09-08.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P3-09-08
Published: 15 February 2022
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Abstract P3-09-07: R-loop forming sequences determine early response genes and tumorigenic pathways driven in BRCA1-deficient carriers

Andre Grageda, Vladimir A Kuznetsov
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-09-07.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P3-09-07
Published: 15 February 2022
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Abstract P3-09-19: The utility of using genomic testing on needle core biopsies during the COVID-19 pandemic: Molecular characterization, risk stratification, neoadjuvant outcome, and future implications

Hani Katerji, Huina Zhang, Xi Wang, Linda Schiffhauer, Ajay Dhakal, Alissa Huston, Carla Falkson, David Hicks, Bradley Turner
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-09-19.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P3-09-19
Published: 15 February 2022
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Abstract P3-09-06: Targeting tumor subpopulations based on single-cell transcriptomics

Jacqueline M Grible, Tess Leftwich, Amy L Olex, Alex K Duong, Nicole Hairr, Narmeen S Rashid, Timothy M Smith, Lia Signaevskaia, David C Boyd, Mikhail G Dozmorov, Joshua C Harrell
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-09-06.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P3-09-06
Published: 15 February 2022
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Abstract P3-09-05: Genomic and clinical characterization of breast tumors with unusual HER2 FISH pattern (ratio < 2, HER2 copy number ≥ 6): Are they mostly HER2 “positive?”

Christina H Wei, Lixin Yang, Daphne Stewart, Victoria Bedell, Daniel Schmolze, Sophia Apple, Joyce L. Murata-Collins, Raju Pillai, Joanne E. Mortimer
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-09-05.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P3-09-05
Published: 15 February 2022
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Abstract P3-09-16: Validating alternative splicing events between bulk and scRNA sequencing data: A bioinformatic approach

Gannon Cottone, Benjamin T Spike, Elnaz Mirzaei Mehrabad, Seema A Khan, Susan Clare
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-09-16.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P3-09-16
Published: 15 February 2022
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Journal Articles

Abstract P3-09-15: Value-added clinical tumor/normal whole exome and whole transcriptome sequencing versus a DNA and RNA tumor only gene panel for managing breast cancer

Kimberly S. Cole, Zhiqiang Li, Amy Tiersten, Wanying Zhang, Hussam Al-Kateb, Feras M. Hantash, Michael R. Rossi, Scott Newman, Xiang Zhou, Eric E. Schadt, Rong Chen, William K. Oh, Marc Y. Fink
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-09-15.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P3-09-15
Published: 15 February 2022
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Journal Articles

Abstract P3-09-14: Whole exome sequencing of matched primary and metastatic triple-negative breast cancer samples

Jaspreet Kaur, Darshan S. Chandrashekar, Zsuzsanna Varga, Emiel Janssen, Khanjan Gandhi, Karuna Mittal, Umay Kiraz, Sooryanarayana Varambally, Ritu Aneja
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-09-14.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P3-09-14
Published: 15 February 2022
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Abstract P3-09-13: Androgen receptor loss is associated with genomic instability characterized by copy number alterations and mirna deregulation in triple-negative breast cancer

Shristi Bhattarai, Bruna M. Sugita, Luciane Cavalli, Ritu Aneja
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-09-13.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P3-09-13
Published: 15 February 2022
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Abstract P3-09-04: Genomic landscape of HER2-negative advanced or metastatic breast cancer with PIK3CA gain-of-function mutations

Jing Xi, Kathleen Harnden, Jingqin Luo, Greg S. Call, Elizabeth Mauer, Karyn Ronski, Cynthia X. Ma, Neil Vasan
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-09-04.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P3-09-04
Published: 15 February 2022
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Abstract P3-09-03: Single nucletotide polymorphisms of aromatase gene (CYP19A1) and toxicity of adjuvant aromatase inhibitors: A translational, prospective study

Benedetta Conte, Chiara Molinelli, Giancarlo Bisagni, Antonio Durando, Giovanni Sanna, Stefania Gori, Ornella Garrone, Stefano Tamberi, Sabino De Placido, Francesco Schettini, Antonio Pazzola, Riccardo Ponzone, Filippo Montemurro, Gianluigi Lunardi, Rosario Notaro, Anna Turletti, Claudia Bighin, Francesca Poggio, Giulia Buzzatti, Matteo Lambertini, Luca Boni, Lucia Del Mastro
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-09-03.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P3-09-03
Published: 15 February 2022
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Abstract P3-09-02: Mutational assessment of newly diagnosed breast cancer using Germline and tumor genomICs

Dilanka L De Silva, Anita R Skandarajah, Michelle Sinclair, Maira Kentwell, Lisa Devereux, Magnus Zeethoven, Kirsten Hogg, Luxi Lal, Lesley Stafford, Paul A James, Geoffrey J Lindeman, Gregory B Mann, Ian G Campbell
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-09-02.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P3-09-02
Published: 15 February 2022
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Abstract P3-09-01: A ubiquitination cascade regulating the integrated stress response and survival in carcinomas

Lisa D Cervia, Tsukasa Shibue, Benjamin Gaeta, Ashir A Borah, Lisa Leung, Naomi Li, Nancy Dumont, Alfredo Gonzalez, Nolan Bick, Mariya Kazachkova, Joshua M Dempster, John M Krill-Burger, Federica Piccioni, Namrata D Udeshi, Meagan E Olive, Steven A Carr, David E Root, James M McFarland, Francisca Vazquez, William C Hahn
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-09-01.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P3-09-01
Published: 15 February 2022
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Abstract P3-09-12: Breast cancer derived GATA3 mutations disrupt luminal transcriptional network

Motoki Takaku, Mika Saotome, Renju Nair
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-09-12.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P3-09-12
Published: 15 February 2022
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Abstract P3-09-11: Clinical characteristics associated withBRCA1/2mutations identified on routine tumor tissue genotyping in metastatic breast cancer

Neelima Vidula, Erica Blouch, Alexander Farahani, Hetal Marble, Andrzej Niemierko, Kathleen Hesler, Elyssa Denault, Dejan Juric, Leif W. Ellisen, Beverly Moy, Steven Isakoff, Jochen Lennerz, Aditya Bardia
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-09-11.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P3-09-11
Published: 15 February 2022
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Abstract P3-09-10: NTRK1/2/3 fusions are observed in both secretory and non-secretory breast cancers

Ethan Sokol, Sophia Maund, Jeffrey Ross, Timothy Wilson
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-09-10.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P3-09-10
Published: 15 February 2022
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Abstract P3-09-09: Serial circulating tumor DNA from patients with metastatic breast cancer with and without BRCA1/2 mutations

Katharine A Collier, David Tallman, Zachary T. Weber, Marcy Haynam, Elizabeth J. Adams, Janet Jenison, Sarah Asad, Maryam Lustberg, Mathew Cherian, Bhuvaneswari Ramaswamy, Sagar Sardesai, Nicole Williams, Robert Wesolowski, Jeffrey Vandeusen, Margaret E. Gatti-Mays, Ashley Pariser, Amir Mortazavi, Daniel G. Stover
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-09-09.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P3-09-09
Published: 15 February 2022
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Abstract P3-09-18: The association between genomic alterations and body mass index in patients with early breast cancer

Ha-Linh Nguyen, Tatjana Geukens, Marion Maetens, Karen Van Baelen, Maxim De Schepper, Sophia Leduc, Edoardo Isnaldi, Sam Aparicio, Ake Borg, Jane Brock, Annegien Broeks, Carlos Caldas, Andrew Green, Hazem Khout, Eyfjörð Jórunn, Stian Knappskog, Savitri Krishnamurthy, Sunil Lakhani, Anita Langerod, John WM Martens, Leigh Murphy, Serena Nik-Zainal, Colin Purdie, Emad Rakha, Andrea Richardson, Anne Salomon, Peter Simpson, Christos Sotiriou, Paul Span, Benita Kiat-Tee Tan, Alastair Thompson, Stefania Tommasi, Marc Van de Vijver, Steven Van Laere, Alain Viari, Giuseppe Floris, Elia Biganzoli, François Richard, Christine Desmedt
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-09-18.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P3-09-18
Published: 15 February 2022
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Abstract P3-09-17: Systems-scale characterization of the human immunome in breast cancer for precision medicine

Stephen Yi
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-09-17.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P3-09-17
Published: 15 February 2022
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Abstract GS3-03: Genomic analysis of 733 HER2+ breast cancers identifies recurrent pathways alterations associated with anti-HER2 resistance and new therapeutic vulnerabilities

Emanuela Ferraro, Alison Smith, Anton Safonov, Paulino Tallon De Lara, Cristina Bernado', Enrique J. Arenas Lahuerta, Joaquín Arribas, David Solit, Jorge S. Reis-Filho, Neal Rosen, Larry Norton, Shanu Modi, Mark E. Robson, Chau T. Dang, Giuseppe Curigliano, Sarat Chandarlapaty, Pedram Razavi
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): GS3-03.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-GS3-03
Published: 15 February 2022
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