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Journal Articles

LncRNA A2M-AS1 Promotes Ferroptosis in Pancreatic Cancer via Interacting With PCBP3

Xin Qiu, Qiuyue Shi, Xianglian Zhang, Xiaoyan Shi, Haixing Jiang, Shanyu Qin

Mol Cancer Res OF1–OF10.

DOI: https://doi.org/10.1158/1541-7786.MCR-22-0024

Published: 07 September 2022

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Includes: Supplementary data

Journal Articles

A Druggable UHRF1/DNMT1/GLI Complex Regulates Sonic Hedgehog–Dependent Tumor Growth

Fan Yang, Jezabel Rodriguez-Blanco, Jun Long, Marzena Swiderska-Syn, Daniel T. Wynn, Bin Li, Chen Shen, Anmada Nayak, Yuguang Ban, Xiaodian Sun, Robert K. Suter, Heather J. McCrea, Anthony J. Capobianco, Nagi G. Ayad, David J. Robbins

Mol Cancer Res OF1–OF13.

DOI: https://doi.org/10.1158/1541-7786.MCR-22-0182

Published: 07 September 2022

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Includes: Supplementary data

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Regulation of Cyclin D1 Degradation by Ubiquitin-Specific Protease 27X Is Critical for Cancer Cell Proliferation and Tumor Growth

Shamshad Alam, Amanda Zunic, Swati Venkat, Michael E. Feigin, Boyko S. Atanassov

Mol Cancer Res OF1–OF12.

DOI: https://doi.org/10.1158/1541-7786.MCR-22-0259

Published: 07 September 2022

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Includes: Supplementary data

Journal Articles

Dependence on the MUC1-C Oncoprotein in Classic, Variant, and Non–neuroendocrine Small Cell Lung Cancer

Atsushi Fushimi, Yoshihiro Morimoto, Satoshi Ishikawa, Nami Yamashita, Atrayee Bhattacharya, Tatsuaki Daimon, Hasan Rajabi, Caining Jin, Masayuki Hagiwara, Yota Yasumizu, Zhou Luan, Wenhao Suo, Kwok-Kin Wong, Henry Withers, Song Liu, Mark D. Long, Donald Kufe

Mol Cancer Res (2022) 20 (9): 1379–1390.

DOI: https://doi.org/10.1158/1541-7786.MCR-22-0165

Published: 02 September 2022

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Includes: Supplementary data

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Loss of E-cadherin Induces IGF1R Activation and Reveals a Targetable Pathway in Invasive Lobular Breast Carcinoma

Ashuvinee Elangovan, Jagmohan Hooda, Laura Savariau, Susrutha Puthanmadhomnarayanan, Megan E. Yates, Jian Chen, Daniel D. Brown, Priscilla F. McAuliffe, Steffi Oesterreich, Jennifer M. Atkinson, Adrian V. Lee

Mol Cancer Res (2022) 20 (9): 1405–1419.

DOI: https://doi.org/10.1158/1541-7786.MCR-22-0090

Published: 02 September 2022

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Ecdysoneless Overexpression Drives Mammary Tumorigenesis through Upregulation of C-MYC and Glucose Metabolism

Mol Cancer Res (2022) 20 (9): 1391–1404.

DOI: https://doi.org/10.1158/1541-7786.MCR-22-0122

Published: 02 September 2022

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Includes: Supplementary data

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Proliferation and Self-Renewal Are Differentially Sensitive to NRAS^G12V Oncogene Levels in an Acute Myeloid Leukemia Cell Line

Morito Kurata, Marie Lue Antony, Klara E. Noble-Orcutt, Susan K. Rathe, Yoonkyu Lee, Hidehiro Furuno, Sachiko Ishibashi, Masumi Ikeda, Kouhei Yamamoto, Masanobu Kitagawa, David A. Largaespada, Zohar Sachs

Mol Cancer Res OF1–OF13.

DOI: https://doi.org/10.1158/1541-7786.MCR-22-0109

Published: 16 August 2022

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CBX8 Together with SET Facilitates Ovarian Carcinoma Growth and Metastasis By Suppressing the Transcription of SUSD2

Yanjie Wu, Yang Duan, Xuanyuan Li, Ran Zhao, Bei Lan, Xingyan Zhang, Xiaochen Wang, Hao Chen, Shengyun Feng, Zhenfeng Liu, Yiming Cheng, Lishan Xi, Yingmei Wang, Fengxia Xue, Chenghao Xuan

Mol Cancer Res OF1–OF12.

DOI: https://doi.org/10.1158/1541-7786.MCR-22-0139

Published: 16 August 2022

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Combinatorial Treatment with PARP-1 Inhibitors and Cisplatin Attenuates Cervical Cancer Growth through Fos-Driven Changes in Gene Expression

Rebecca Gupte, Ken Y. Lin, Tulip Nandu, Jayanthi S. Lea, W. Lee Kraus

Mol Cancer Res (2022) 20 (8): 1183–1192.

DOI: https://doi.org/10.1158/1541-7786.MCR-22-0111

Published: 05 August 2022

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Phosphoproteomics Reveals the Role of Constitutive KAP1 Phosphorylation by B-cell Receptor Signaling in Chronic Lymphocytic Leukemia

Jung-Lin Wu, Hsin-Yi Wu, Shang-Ju Wu, Ho-Yang Tsai, Shao-Hsing Weng, Kuen-Tyng Lin, Liang-In Lin, Chi-Yuan Yao, Margarita Zamanova, Yi-Yuan Lee, Takashi Angata, Hwei-Fang Tien, Yu-Ju Chen, Kuo-I Lin

Mol Cancer Res (2022) 20 (8): 1222–1232.

DOI: https://doi.org/10.1158/1541-7786.MCR-21-0722

Published: 05 August 2022

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Journal Articles

Loss of PBRM1 Alters Promoter Histone Modifications and Activates ALDH1A1 to Drive Renal Cell Carcinoma

David A. Schoenfeld, Royce Zhou, Sakellarios Zairis, William Su, Nicole Steinbach, Deepti Mathur, Ankita Bansal, Alexis L. Zachem, Bertilia Tavarez, Dan Hasson, Emily Bernstein, Raul Rabadan, Ramon Parsons

Mol Cancer Res (2022) 20 (8): 1193–1207.

DOI: https://doi.org/10.1158/1541-7786.MCR-21-1039

Published: 05 August 2022

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Stromal p53 Regulates Breast Cancer Development, the Immune Landscape, and Survival in an Oncogene-Specific Manner

Jinghai Wu, Xin Liu, Julie A. Wallace Reeser, Anthony J. Trimboli, Thierry Pécot, Gina M. Sizemore, Shan K. Naidu, Soledad A. Fernandez, Lianbo Yu, Michael Hallett, Morag Park, Gustavo W. Leone, Blake E. Hildreth, III, Michael C. Ostrowski

Mol Cancer Res (2022) 20 (8): 1233–1246.

DOI: https://doi.org/10.1158/1541-7786.MCR-21-0960

Published: 05 August 2022

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Includes: Supplementary data

Journal Articles

MUC16 Promotes Liver Metastasis of Pancreatic Ductal Adenocarcinoma by Upregulating NRP2-Associated Cell Adhesion

Saravanakumar Marimuthu, Imayavaramban Lakshmanan, Sakthivel Muniyan, Shailendra K. Gautam, Rama Krishna Nimmakayala, Sanchita Rauth, Pranita Atri, Ashu Shah, Namita Bhyravbhatla, Kavita Mallya, Paul M. Grandgenett, Michael A. Hollingsworth, Kaustubh Datta, Maneesh Jain, Moorthy P. Ponnusamy, Surinder K. Batra

Mol Cancer Res (2022) 20 (8): 1208–1221.

DOI: https://doi.org/10.1158/1541-7786.MCR-21-0888

Published: 05 August 2022

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Includes: Supplementary data

Journal Articles

TGF-β-Induced FLRT3 Attenuation Is Essential for Cancer-Associated Fibroblast–Mediated Epithelial–Mesenchymal Transition in Colorectal Cancer

Mengdi Yang, Dan Li, Zhiyuan Jiang, Changcan Li, Suyuan Ji, Jing Sun, Yujie Chang, Shunyi Ruan, Zhiyu Wang, Rui Liang, Xueyu Dai, Bin Li, Hui Zhao

Mol Cancer Res (2022) 20 (8): 1247–1259.

DOI: https://doi.org/10.1158/1541-7786.MCR-21-0924

Published: 05 August 2022

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Includes: Supplementary data

Journal Articles

TRAF4 Inhibits Bladder Cancer Progression by Promoting BMP/SMAD Signaling

Prasanna Vasudevan Iyengar, Dieuwke Louise Marvin, Dilraj Lama, Tuan Zea Tan, Sudha Suriyamurthy, Feng Xie, Maarten van Dinther, Hailiang Mei, Chandra Shekhar Verma, Long Zhang, Laila Ritsma, Peter ten Dijke

Mol Cancer Res OF1–OF16.

DOI: https://doi.org/10.1158/1541-7786.MCR-20-1029

Published: 28 July 2022

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Comprehensive Viral Genotyping Reveals Prognostic Viral Phylogenetic Groups in HPV16-Associated Squamous Cell Carcinoma of the Oropharynx

Travis P. Schrank, Lee Landess, Wesley H. Stepp, Hina Rehmani, William H. Weir, Nicholas Lenze, Asim Lal, Di Wu, Aditi Kothari, Trevor G. Hackman, Siddharth Sheth, Shetal Patel, Stuart R. Jefferys, Natalia Issaeva, Wendell G. Yarbrough

Mol Cancer Res OF1–OF13.

DOI: https://doi.org/10.1158/1541-7786.MCR-21-0443

Published: 19 July 2022

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Includes: Supplementary data

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Mitochondrial Dysfunction Is a Driver of SP-2509 Drug Resistance in Ewing Sarcoma

E. John Tokarsky, Jesse C. Crow, Lillian M. Guenther, John Sherman, Cenny Taslim, Gabriela Alexe, Kathleen I. Pishas, Galen Rask, Blake S. Justis, Ana Kasumova, Kimberly Stegmaier, Stephen L. Lessnick, Emily R. Theisen

Mol Cancer Res (2022) 20 (7): 1035–1046.

DOI: https://doi.org/10.1158/1541-7786.MCR-22-0027

Published: 06 July 2022

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Includes: Supplementary data

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EXOC4 Promotes Diffuse-Type Gastric Cancer Metastasis via Activating FAK Signal

Haojie Li, Xuhong Fu, Junjie Zhao, Chen Li, Lingmeng Li, Peiyan Xia, Jianping Guo, Wenyi Wei, Rong Zeng, Jiarui Wu, Yihong Sun, Liyu Huang, Xuefei Wang

Mol Cancer Res (2022) 20 (7): 1021–1034.

DOI: https://doi.org/10.1158/1541-7786.MCR-21-0441

Published: 06 July 2022

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Includes: Supplementary data

Journal Articles

VPRBP Functions Downstream of the Androgen Receptor and OGT to Restrict p53 Activation in Prostate Cancer

Ninu Poulose, Nicholas Forsythe, Adam Polonski, Gemma Gregg, Sarah Maguire, Marc Fuchs, Sarah Minner, Guido Sauter, Simon S. McDade, Ian G. Mills

Mol Cancer Res (2022) 20 (7): 1047–1060.

DOI: https://doi.org/10.1158/1541-7786.MCR-21-0477

Published: 06 July 2022

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Journal Articles

In Vitro Insertional Mutagenesis Screen Identifies Novel Genes Driving Breast Cancer Metastasis

Csaba Miskey, Lacramioara Botezatu, Nuri A. Temiz, Andreas Gogol-Döring, Áron Bartha, Balázs Győrffy, David A. Largaespada, Zoltán Ivics, Attila Sebe

Mol Cancer Res OF1–OF14.

DOI: https://doi.org/10.1158/1541-7786.MCR-21-0772

Published: 23 June 2022

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Includes: Supplementary data

2 3 4 5

NARROW

LncRNA A2M-AS1 Promotes Ferroptosis in Pancreatic Cancer via Interacting With PCBP3

A Druggable UHRF1/DNMT1/GLI Complex Regulates Sonic Hedgehog–Dependent Tumor Growth

Regulation of Cyclin D1 Degradation by Ubiquitin-Specific Protease 27X Is Critical for Cancer Cell Proliferation and Tumor Growth

Dependence on the MUC1-C Oncoprotein in Classic, Variant, and Non–neuroendocrine Small Cell Lung Cancer

Loss of E-cadherin Induces IGF1R Activation and Reveals a Targetable Pathway in Invasive Lobular Breast Carcinoma

Ecdysoneless Overexpression Drives Mammary Tumorigenesis through Upregulation of C-MYC and Glucose Metabolism

Proliferation and Self-Renewal Are Differentially Sensitive to NRAS^G12V Oncogene Levels in an Acute Myeloid Leukemia Cell Line

CBX8 Together with SET Facilitates Ovarian Carcinoma Growth and Metastasis By Suppressing the Transcription of SUSD2

Combinatorial Treatment with PARP-1 Inhibitors and Cisplatin Attenuates Cervical Cancer Growth through Fos-Driven Changes in Gene Expression

Phosphoproteomics Reveals the Role of Constitutive KAP1 Phosphorylation by B-cell Receptor Signaling in Chronic Lymphocytic Leukemia

Loss of PBRM1 Alters Promoter Histone Modifications and Activates ALDH1A1 to Drive Renal Cell Carcinoma

Stromal p53 Regulates Breast Cancer Development, the Immune Landscape, and Survival in an Oncogene-Specific Manner

MUC16 Promotes Liver Metastasis of Pancreatic Ductal Adenocarcinoma by Upregulating NRP2-Associated Cell Adhesion

TGF-β-Induced FLRT3 Attenuation Is Essential for Cancer-Associated Fibroblast–Mediated Epithelial–Mesenchymal Transition in Colorectal Cancer

TRAF4 Inhibits Bladder Cancer Progression by Promoting BMP/SMAD Signaling

Comprehensive Viral Genotyping Reveals Prognostic Viral Phylogenetic Groups in HPV16-Associated Squamous Cell Carcinoma of the Oropharynx

Mitochondrial Dysfunction Is a Driver of SP-2509 Drug Resistance in Ewing Sarcoma

EXOC4 Promotes Diffuse-Type Gastric Cancer Metastasis via Activating FAK Signal

VPRBP Functions Downstream of the Androgen Receptor and OGT to Restrict p53 Activation in Prostate Cancer

In Vitro Insertional Mutagenesis Screen Identifies Novel Genes Driving Breast Cancer Metastasis

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AACR Journals

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