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Leonardo Giovannoni
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Journal Articles

Targeting Interleukin-2 to the Bone Marrow Stroma for Therapy of Acute Myeloid Leukemia Relapsing after Allogeneic Hematopoietic Stem Cell Transplantation

Christoph Schliemann, Katrin L. Gutbrodt, Andrea Kerkhoff, Michele Pohlen, Stefanie Wiebe, Gerda Silling, Linus Angenendt, Torsten Kessler, Rolf M. Mesters, Leonardo Giovannoni, Michael Schäfers, Bianca Altvater, Claudia Rossig, Inga Grünewald, Eva Wardelmann, Gabriele Köhler, Dario Neri, Matthias Stelljes, Wolfgang E. Berdel
Journal: Cancer Immunology Research
Cancer Immunol Res (2015) 3 (5): 547–556.
DOI: https://doi.org/10.1158/2326-6066.CIR-14-0179
Published: 03 May 2015
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Journal Articles

Intralesional Treatment of Stage III Metastatic Melanoma Patients with L19–IL2 Results in Sustained Clinical and Systemic Immunologic Responses

Benjamin Weide, Thomas K. Eigentler, Annette Pflugfelder, Henning Zelba, Alexander Martens, Graham Pawelec, Leonardo Giovannoni, Pier Adelchi Ruffini, Giuliano Elia, Dario Neri, Ralf Gutzmer, Jürgen C. Becker, Claus Garbe
Journal: Cancer Immunology Research
Cancer Immunol Res (2014) 2 (7): 668–678.
DOI: https://doi.org/10.1158/2326-6066.CIR-13-0206
Published: 01 July 2014
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Includes: Supplementary data
Journal Articles

Radretumab Radioimmunotherapy in Patients with Brain Metastasis: A 124I-L19SIP Dosimetric PET Study

Gian Luca Poli, Claudia Bianchi, Giorgio Virotta, Anna Bettini, Renzo Moretti, Eveline Trachsel, Giuliano Elia, Leonardo Giovannoni, Dario Neri, Andrea Bruno
Journal: Cancer Immunology Research
Cancer Immunol Res (2013) 1 (2): 134–143.
DOI: https://doi.org/10.1158/2326-6066.CIR-13-0007
Published: 07 August 2013
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Includes: Supplementary data
Journal Articles

A Dose-Escalation and Signal-Generating Study of the Immunocytokine L19-IL2 in Combination with Dacarbazine for the Therapy of Patients with Metastatic Melanoma

Thomas K. Eigentler, Benjamin Weide, Filippo de Braud, Gianluca Spitaleri, Antonella Romanini, Annette Pflugfelder, Reinerio González-Iglesias, Annaelisa Tasciotti, Leonardo Giovannoni, Kathrin Schwager, Valeria Lovato, Manuela Kaspar, Eveline Trachsel, Hans D. Menssen, Dario Neri, Claus Garbe
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (24): 7732–7742.
DOI: https://doi.org/10.1158/1078-0432.CCR-11-1203
Published: 18 December 2011
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Includes: Supplementary data
Journal Articles

Abstract B55: Phase I/II study of the tumor‐targeting human L19TNF‐monoclonal antibody‐cytokine fusion protein in patients with advanced solid tumors

Gianluca Spitaleri, Tommaso M. De Pas, Cristina Noberasco, Leonardo Giovannoni, Hans D. Menseen, Luciano Zardi, Francesca Toffalorio, Chiara Catania, Alessandra Milani, Sabrina Boselli, Dario Neri, Filippo de Braud
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (12_Supplement): B55.
DOI: https://doi.org/10.1158/1535-7163.TARG-09-B55
Published: 10 December 2009
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Antibody-Mediated Delivery of Interleukin-2 to the Stroma of Breast Cancer Strongly Enhances the Potency of Chemotherapy

Jessica Mårlind, Manuela Kaspar, Eveline Trachsel, Roberto Sommavilla, Stuart Hindle, Camilla Bacci, Leonardo Giovannoni, Dario Neri
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (20): 6515–6524.
DOI: https://doi.org/10.1158/1078-0432.CCR-07-5041
Published: 16 October 2008
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Includes: Supplementary data
Journal Articles

Immunomodulatory effects of recombinant fusion protein L19-IL2 in patients with refractory solid tumors

Filippo de Braud, Giuseppe Curigliano, Gianluca Spitaleri, Tommaso De Pas, Cristina Noberasco, Leonardo Giovannoni, Luciano Zardi, Hans Menssen, Alessandra Milani, Dario Neri
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 912.
Published: 01 May 2007
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Journal Articles

Immunoscintigraphic Detection of the ED-B Domain of Fibronectin, a Marker of Angiogenesis, in Patients with Cancer

Monica Santimaria, Giovanni Moscatelli, Giuseppe L. Viale, Leonardo Giovannoni, Giovanni Neri, Francesca Viti, Alessandra Leprini, Laura Borsi, Patrizia Castellani, Luciano Zardi, Dario Neri, Pietro Riva
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (2): 571–579.
Published: 01 February 2003
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Increased Binding Affinity and Valence of Recombinant Antibody Fragments Lead to Improved Targeting of Tumoral Angiogenesis

Francesca Viti, Lorenzo Tarli, Leonardo Giovannoni, Luciano Zardi, Dario Neri
Journal: Cancer Research
Cancer Res (1999) 59 (2): 347–352.
Published: 01 January 1999
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