Journal Club:
Blood Cancer Discovery with Drs. Meng Li and Ari Melnick

Moderated by: Tanya Bondar, PhD
Deputy Editor, Blood Cancer Discovery
Recorded: 02/07/2022

Watch the recording of the AACR Journal Club session featuring Drs. Meng Li and Ari Melnick, discussing their article recently published in Blood Cancer Discovery, "Translational Activation of ATF4 through Mitochondrial Anaplerotic Metabolic Pathways Is Required for DLBCL Growth and Survival." DLBCL is the most common blood cancer type, and is also one of the fastest-growing human tumors. The work by Li and Melnick elucidates metabolic circuits fueling DLBCL extraordinary growth rate, and paves the way to therapeutically targeting DLBCL through its metabolic dependencies.

Stay tuned for the Q&A session at the end of the recording.

About the Featured Speakers:

Meng Li, PhD, is an Instructor of Cancer Genomics in Medicine at the Weill Cornell University. His research in Dr. Ari Melnick’s lab is focused on molecular metabolism fueling aggressive growth of lymphoma cells, and on ways to targeting it for therapy.

Ari M. Melnick, MD, is a Gebroe Professor of Hematology, Medical Oncology, Immunology and Pharmacology at Weill Cornell Medicine, where he also serves as a Director of the Sackler Center for Biomedical and Physical Sciences.