Cancer Hallmarks

Review

Immune Potential Untapped: Leveraging the Lymphatic System for Cancer Immunotherapy

Amanda W. Lund

Doi: 10.1158/2326-6066.CIR-22-0266

Research Article

Endothelial RBPJ Is Essential for the Education of Tumor-Associated Macrophages

Elisenda Alsina-Sanchis; Ronja Mülfarth; Iris Moll; Sarah Böhn; Lena Wiedmann; Lorea Jordana-Urriza; Tara Ziegelbauer; Eleni Zimmer; Jacqueline Taylor; Francesca De Angelis Rigotti; Adrian Stögbauer; Benedetto Daniele Giaimo; Adelheid Cerwenka; Tilman Borggrefe; Andreas Fischer; Juan Rodriguez-Vita

Doi: 10.1158/0008-5472.CAN-22-0076

Research Article

Three-dimensional Imaging Reveals Immune-driven Tumor-associated High Endothelial Venules as a Key Correlate of Tumor Rejection Following Depletion of Regulatory T Cells

Stefan Milutinovic; Jun Abe; Emma Jones; Inken Kelch; Kathryn Smart; Sarah N. Lauder; Michelle Somerville; Carl Ware; Andrew Godkin; Jens V. Stein; Gib Bogle; Awen Gallimore

Doi: 10.1158/2767-9764.CRC-21-0123

Research Article

Endothelial VEGFR Coreceptors Neuropilin-1 and Neuropilin-2 Are Essential for Tumor Angiogenesis

Christopher J. Benwell; Robert T. Johnson; James A.G.E. Taylor; Christopher A. Price; Stephen D. Robinson

Doi: 10.1158/2767-9764.CRC-22-0250

Research Article

CD248 Regulates Wnt Signaling in Pericytes to Promote Angiogenesis and Tumor Growth in Lung Cancer

Chia-Lun Hong; I-Shing Yu; Chen-Hsueh Pai; Jin-Shing Chen; Min-Shu Hsieh; Hua-Lin Wu; Shu-Wha Lin; Hsiang-Po Huang

Doi: 10.1158/0008-5472.CAN-22-1695

Research Article

A Novel PHD2/VHL-mediated Regulation of YAP1 Contributes to VEGF Expression and Angiogenesis

Namrata Bora-Singhal; Biswarup Saha; Durairaj Mohankumar; Jaya Padmanabhan; Domenico Coppola; Srikumar Chellappan

Doi: 10.1158/2767-9764.CRC-21-0084

Research Article

Liver Endothelium Promotes HER3-Mediated Cell Survival in Colorectal Cancer with Wild-Type and Mutant KRAS

Moeez Rathore; Wei Zhang; Michel'le Wright; Rajat Bhattacharya; Fan Fan; Ali Vaziri-Gohar; Jordan Winter; Zhenghe Wang; Sanford D. Markowitz; Joseph Willis; Lee M. Ellis; Rui Wang

Doi: 10.1158/1541-7786.MCR-21-0633

Research Article

δ-Tocotrienol is the Most Potent Vitamin E Form in Inhibiting Prostate Cancer Cell Growth and Inhibits Prostate Carcinogenesis in Pten^p−/− Mice

Hong Wang; William Yan; Yuhai Sun; Chung S. Yang

Doi: 10.1158/1940-6207.CAPR-21-0508

Research Article

Molecular Signature of Tumor-Associated High Endothelial Venules That Can Predict Breast Cancer Survival

Junko Sawada; Nobuyoshi Hiraoka; Rongsu Qi; Lu Jiang; Ashley E. Fournier-Goss; Masayuki Yoshida; Hiroto Kawashima; Masanobu Komatsu

Doi: 10.1158/2326-6066.CIR-21-0369

Cancer Research Landmark

Antiangiogenesis: Vessel Regression, Vessel Normalization, or Both?

Hellmut G. Augustin; Gou Young Koh

Doi: 10.1158/0008-5472.CAN-21-3515