Skip to Main Content

Advertisement

Skip Nav Destination

Cancer Hallmarks

Presented by the AACR Journals

 

 

 

Enabling Replicative Immortality

Research Article

A Novel Type of Monocytic Leukemia Stem Cell Revealed by the Clinical Use of Venetoclax-Based Therapy

Shanshan Pei; Ian T. Shelton; Austin E. Gillen; Brett M. Stevens; Maura Gasparetto; Yanan Wang; Lina Liu; Jun Liu; Tonya M. Brunetti; Krysta Engel; Sarah Staggs; William Showers; Anagha Inguva Sheth; Maria L. Amaya; Mohammad Minhajuddin; Amanda Winters; Sweta B. Patel; Hunter Tolison; Anna E. Krug; Tracy N. Young; Jeffrey Schowinsky; Christine M. McMahon; Clayton A. Smith; Daniel A. Pollyea; Craig T. Jordan

Doi: 10.1158/2159-8290.CD-22-1297

Research Article

Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia

Winnie L. Kan; Urmi Dhagat; Kerstin B. Kaufmann; Timothy R. Hercus; Tracy L. Nero; Andy G.X. Zeng; John Toubia; Emma F. Barry; Sophie E. Broughton; Guillermo A. Gomez; Brooks A. Benard; Mara Dottore; Karen S. Cheung Tung Shing; Héléna Boutzen; Saumya E. Samaraweera; Kaylene J. Simpson; Liqing Jin; Gregory J. Goodall; C. Glenn Begley; Daniel Thomas; Paul G. Ekert; Denis Tvorogov; Richard J. D'Andrea; John E. Dick; Michael W. Parker; Angel F. Lopez

Doi: 10.1158/2159-8290.CD-22-1396

Research Article

Distinct IDH1/2-associated Methylation Profile and Enrichment of TP53 and TERT Mutations Distinguish Dedifferentiated Chondrosarcoma from Conventional Chondrosarcoma

Josephine Kam Tai Dermawan; Khedoujia Nafa; Abhinita Mohanty; Yingjuan Xu; Ivelise Rijo; Jacklyn Casanova; Liliana Villafania; Jamal Benhamida; Ciara M. Kelly; William D. Tap; Patrick J. Boland; Nicola Fabbri; John H. Healey; Marc Ladanyi; Chao Lu; Meera Hameed

Doi: 10.1158/2767-9764.CRC-22-0397

Research Article

MEK5-ERK5 Axis Promotes Self-renewal and Tumorigenicity of Glioma Stem Cells

Kazuya Fukasawa; Jiajun Lyu; Takuya Kubo; Yuki Tanaka; Akane Suzuki; Tetsuhiro Horie; Akane Tomizawa; Ryoma Osumi; Sayuki Iwahashi; Kazuya Tokumura; Misato Murata; Masaki Kobayashi; Tomoki Todo; Atsushi Hirao; Eiichi Hinoi

Doi: 10.1158/2767-9764.CRC-22-0243

Research Article

Transglutaminase 2 Binds to the CD44v6 Cytoplasmic Domain to Stimulate CD44v6/ERK1/2 Signaling and Maintain an Aggressive Cancer Phenotype

Xi Chen; Gautam Adhikary; John J. Newland; Wen Xu; Jeffrey W. Keillor; David J. Weber; Richard L. Eckert

Doi: 10.1158/1541-7786.MCR-23-0051

Small Model Therapeutics

4′-Ethynyl-2′-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress

Marissa L. Calbert; Gurushankar Chandramouly; Clare M. Adams; Magali Saez-Ayala; Tatiana Kent; Mrityunjay Tyagi; V.S.S. Abhinav Ayyadevara; Yifan Wang; John J. Krais; John Gordon; Jessica Atkins; Monika M. Toma; Stéphane Betzi; Andrew S. Boghossian; Matthew G. Rees; Melissa M. Ronan; Jennifer A. Roth; Aaron R. Goldman; Nicole Gorman; Ramkrishna Mitra; Wayne E. Childers; Xavier Graña; Tomasz Skorski; Neil Johnson; Christian Hurtz; Xavier Morelli; Christine M. Eischen; Richard T. Pomerantz

Doi: 10.1158/1535-7163.MCT-23-0487

Research Article

Distinct IDH1/2-associated Methylation Profile and Enrichment of TP53 and TERT Mutations Distinguish Dedifferentiated Chondrosarcoma from Conventional Chondrosarcoma

Josephine Kam Tai Dermawan; Khedoujia Nafa; Abhinita Mohanty; Yingjuan Xu; Ivelise Rijo; Jacklyn Casanova; Liliana Villafania; Jamal Benhamida; Ciara M. Kelly; William D. Tap; Patrick J. Boland; Nicola Fabbri; John H. Healey; Marc Ladanyi; Chao Lu; Meera Hameed

Doi: 10.1158/2767-9764.CRC-22-0397

Research Article

Intronic Cis-Element DR8 in hTERT Is Bound by Splicing Factor SF3B4 and Regulates hTERT Splicing in Non–Small Cell Lung Cancer

Aaron L. Slusher; Jeongjin J. Kim; Mark Ribick; Jesse Pollens-Voigt; Armand Bankhead, III; Phillip L. Palmbos; Andrew T. Ludlow

Doi: 10.1158/1541-7786.MCR-21-0058

Research Article

Alternative Lengthening of Telomeres in Cancer Confers a Vulnerability to Reactivation of p53 Function

Shawn J. Macha; Balakrishna Koneru; Trevor A. Burrow; Charles Zhu; Dzmitry Savitski; Rakhshanda L. Rahman; Catherine A. Ronaghan; Jonas Nance; Kristyn McCoy; Cody Eslinger; C. Patrick Reynolds

Doi: 10.1158/0008-5472.CAN-22-0125

Research Article

Suppressed Cellular Senescence Mediated by T-box3 in Aged Gastric Epithelial Cells may Contribute to Aging-related Carcinogenesis

Akio Takeuchi; Naoki Asano; Akira Imatani; Masashi Saito; Xiaoyi Jin; Masahiro Saito; Takeshi Kanno; Waku Hatta; Kaname Uno; Tomoyuki Koike; Atsushi Masamune

Doi: 10.1158/2767-9764.CRC-22-0084

Research Article

Protein Phosphatase 2A–Dependent Mitotic hnRNPA1 Dephosphorylation and TERRA Formation Facilitate Telomere Capping

Jiang-Dong Sui; Zheng Tang; Benjamin P.C. Chen; Ping Huang; Meng-Qi Yang; Nuo-Han Wang; Hao-Nan Yang; Hong-Lei Tu; Qing-Ming Jiang; Jing Zhang; Ying Wang; Yong-Zhong Wu

Doi: 10.1158/1541-7786.MCR-21-0581

Close Modal

or Create an Account

Close Modal
Close Modal