2023
AACR offers monthly "Editors' Picks" from our journals. We highlight one article from each issue that has been determined a "must read" by the Editors. Be sure to bookmark this page, as it will be updated on a monthly basis.
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March
Blood Cancer Discovery
Adult Low-Hypodiploid Acute Lymphoblastic Leukemia Emerges from Preleukemic TP53-Mutant Clonal Hematopoiesis
Blood Cancer Discovery March 2023
Cancer Discovery
Racial/Ethnic and Sex Differences in Somatic Cancer Gene Mutations among Patients with Early-Onset Colorectal Cancer
Cancer Discov March 2023
Cancer Epidemiology, Biomarkers & Prevention
Association of Urinary Biomarkers of Smoking-Related Toxicants with Lung Cancer Incidence in Smokers: The Multiethnic Cohort Study
Cancer Epidemiol Bio Prev March 2023
Cancer Immunology Research
Syntaphilin Regulates Neutrophil Migration in Cancer
Cancer Immunol Res March 2023
Cancer Prevention Research
Benign Breast Disease, NSAIDs, and Postmenopausal Breast Cancer Risk in the CPS-II Cohort
Cancer Prev Res March 2023
Cancer Research
Stromal Reprogramming through Dual PDGFRα/β Blockade Boosts the Efficacy of Anti–PD-1 Immunotherapy in Fibrotic Tumors
Cancer Res March 2023
Olig1/2-Expressing Intermediate Lineage Progenitors Are Predisposed to PTEN/p53-Loss–Induced Gliomagenesis and Harbor Specific Therapeutic Vulnerabilities
Cancer Res March 2023
Clinical Cancer Research
Beneficial Effects of Mifepristone Treatment in Patients with Breast Cancer Selected by the Progesterone Receptor Isoform Ratio: Results from the MIPRA Trial
Clin Cancer Res March 2023
A Phase Ib/II Trial of Combined BRAF and EGFR Inhibition in BRAF V600E Positive Metastatic Colorectal Cancer and Other Cancers: The EVICT (Erlotinib and Vemurafenib In Combination Trial) Study
Clin Cancer Res March 2023
Molecular Cancer Research
ATM Regulation of the Cohesin Complex Is Required for Repression of DNA Replication and Transcription in the Vicinity of DNA Double-Strand Breaks
Mol Cancer Res March 2023
Molecular Cancer Therapeutics
Interplay Between Extracellular Matrix Remodeling and Angiogenesis in Tumor Ecosystem
Mol Cancer Ther March 2023
Cancer Research Communications
Phase I Trial of Intravenous Mistletoe Extract in Advanced Cancer
Cancer Res Commun March 2023
February
Blood Cancer Discovery
Distinct Genetically Determined Origins of Myd88/BCL2-Driven Aggressive Lymphoma Rationalize Targeted Therapeutic Intervention Strategies
Blood Cancer Discovery January 2023
Cancer Discovery
Efficacy of a Small-Molecule Inhibitor of KrasG12D in Immunocompetent Models of Pancreatic Cancer
Cancer Discov February 2023
Cancer Epidemiology, Biomarkers & Prevention
Race Differences in Patient-Reported Symptoms during Chemotherapy among Women with Early-Stage Hormone Receptor–Positive Breast Cancer
Cancer Epidemiol Bio Prev February 2023
Cancer Immunology Research
Rational Protein Design Yields a CD20 CAR with Superior Antitumor Efficacy Compared with CD19 CAR
Cancer Immunol Res February 2023
Cancer Prevention Research
Plasma Concentrations of Gut Hormones Acyl Ghrelin and Peptide YY and Subsequent Risk of Colorectal Cancer and Molecular Tumor Subtypes
Cancer Prev Res February 2023
Cancer Research
Single-Cell Analysis in Lung Adenocarcinoma Implicates RNA Editing in Cancer Innate Immunity and Patient Prognosis
Cancer Res February 2023
The Cytidine Deaminase APOBEC3G Contributes to Cancer Mutagenesis and Clonal Evolution in Bladder Cancer
Cancer Res February 2023
Clinical Cancer Research
Clinical Features Associated with Outcomes and Biomarker Analysis of Dabrafenib plus Trametinib Treatment in Patients with BRAF-Mutant Melanoma Brain Metastases
Clin Cancer Res February 2023
Five-Year Clinical Outcomes after Neoadjuvant Nivolumab in Resectable Non–Small Cell Lung Cancer
Clin Cancer Res February 2023
Molecular Cancer Research
BET Inhibitors Target the SCLC-N Subtype of Small-Cell Lung Cancer by Blocking NEUROD1 Transactivation
Mol Cancer Res February 2023
Molecular Cancer Therapeutics
Discovery of STRO-002, a Novel Homogeneous ADC Targeting Folate Receptor Alpha, for the Treatment of Ovarian and Endometrial Cancers
Mol Cancer Ther February 2023
Cancer Research Communications
Incorporating RNA-based Risk Scores for Genomic Instability to Predict Breast Cancer Recurrence and Immunogenicity in a Diverse Population
Cancer Res Commun January 2023
January
Blood Cancer Discovery
Extracellular Vesicle Secretion by Leukemia Cells In Vivo Promotes CLL Progression by Hampering Antitumor T-cell Responses
Blood Cancer Discovery January 2023
Cancer Discovery
Creating MHC-Restricted Neoantigens with Covalent Inhibitors That Can Be Targeted by Immune Therapy
Cancer Discov January 2023
Cancer Epidemiology, Biomarkers & Prevention
Impact and Recovery from COVID-19–Related Disruptions in Colorectal Cancer Screening and Care in the US: A Scenario Analysis
Cancer Epidemiol Bio Prev January 2023
Cancer Immunology Research
The Conventional Dendritic Cell 1 Subset Primes CD8+ T Cells and Traffics Tumor Antigen to Drive Antitumor Immunity in the Brain
Cancer Immunol Res January 2023
Cancer Prevention Research
Phase I Dose Escalation Study of Topical Bexarotene in Women at High Risk for Breast Cancer
Cancer Prev Res January 2023
Cancer Research
Spatial Transcriptomic Analysis of a Diverse Patient Cohort Reveals a Conserved Architecture in Triple-Negative Breast Cancer
Cancer Res January 2023
Mitochondrial Uncoupling Induces Epigenome Remodeling and Promotes Differentiation in Neuroblastoma
Cancer Res January 2023
Clinical Cancer Research
Pilot Study of ONCOS-102 and Pembrolizumab: Remodeling of the Tumor Microenvironment and Clinical Outcomes in Anti–PD-1–Resistant Advanced Melanoma
Clin Cancer Res January 2023
Intraperitoneal Monocytes plus IFNs as a Novel Cellular Immunotherapy for Ovarian Cancer: Mechanistic Characterization and Results from a Phase I Clinical Trial
Clin Cancer Res January 2023
Molecular Cancer Research
Mitochondrial Aconitase ACO2 Links Iron Homeostasis with Tumorigenicity in Non–Small Cell Lung Cancer
Mol Cancer Res January 2023
Molecular Cancer Therapeutics
Antibody–Drug Conjugate Sacituzumab Govitecan Drives Efficient Tissue Penetration and Rapid Intracellular Drug Release
Mol Cancer Ther January 2023
Cancer Research Communications
Complex Patterns of Genomic Heterogeneity Identified in 42 Tumor Samples and ctDNA of a Pulmonary Atypical Carcinoid Patient
Cancer Res Commun January 2023
