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The Best of the AACR Journals Collection: Author Profiles

photo of Christopher I. Amos

Christopher I. Amos

Title & Affiliation:
Director of the Institute for Clinical and Translational Research and Professor of Medicine, Department of Medicine, Baylor College of Medicine
Houston, Texas

Most-cited Article:
The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers

Q: What is your primary area of study/research?
A: Genetic epidemiology

Q: What influenced your decision to embark on a research career?
A: My interest in understanding the biological processes that influence complex disease and cancer development. The development of new approaches of genetic analysis was leading to an explosion in the need for mathematical modeling and information technologies. The ability to work at a crossroads of biology and statistics allowed me to develop new approaches for understanding cancer etiology.

Q; What excites you most about your research area?
A: New technologies and approaches to modeling are giving us great insights into the joint effects of environmental and genetic contributions to the causes of cancer. The ability to profile hundreds of thousands of cancer cases and controls has given us thousands of new insights and has allowed us to identify, through mediation and Mendelian randomization approaches, a great diversity of new candidates, influencing early stages of cancer development. These observations will lead to a much more precise knowledge of the key steps that influence the development of all common cancers.

Q: What are your hobbies or passions outside of work?
A: I ride my bike daily, no matter what the weather may bring. It’s a great way to see Houston. At Dartmouth, I enjoyed helping lead The Prouty bike ride, which was key to fundraising for cancer research support. I also enjoy skiing, hiking and running.


Read The Best of the AACR Journals


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