AACR Annual Meeting 2023:
AACR Journals’ Simultaneous Publications
AACR journal articles listed below were published concurrently with presentations during the AACR Annual Meeting 2023.
Sunday, April 16, 2023
A transcriptome-based precision oncology platform for patient-therapy alignment in a diverse set of treatment resistant malignancies
Andrea Califano, et al.
Integrative analysis of a large real-world cohort of small cell lung cancer identifies distinct genetic subtypes and insights into histological transformation
Christine M. Lovly, et al.
High Expression of MHC Class I Overcomes Cancer Immunotherapy Resistance Due to IFNγ Signaling Pathway Defects
Yosuke Togashi, et al.
Metabolic reprogramming driven by IGF2BP3 promotes acquired resistance to EGFR inhibitors in non-small cell lung cancer
Xiaolei Zhang, et al.
Tumor-Agnostic Precision Medicine from the AACR GENIE Database: Clinical Implications
Mohamed Gouda / Vivek Subbiah, et al.
Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression
Gina M. DeNicola, et al.
Monday, April 17, 2023
Racial/Ethnic Disparities in Cervical Cancer Stage at Diagnosis: Mediating Effects of Neighborhood-level Socioeconomic Deprivation
Itunu Sokale, et al.
FOXA2 Cooperates with Mutant KRAS to Drive Invasive Mucinous Adenocarcinoma of the Lung
Yutaka Maeda, et al.
BZW2 Inhibition Reduces Colorectal Cancer Growth and Metastasis
Upender Manne, et al.
Converging on a Cure: The Roads to Predictive Immunotherapy
Elana Fertig, et al.
Stressful Life Events, Social Support, and Incident Breast Cancer by Estrogen Receptor Status
Wayne R Lawrence, et al.
Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor-Initiating Cells
V. Wee Yong, et al.
METTL3-Mediated m6A Modification Controls Splicing Factor Abundance and Contributes to Aggressive CLL
Lili Wang, et al.
Patient-Derived iPSCs Faithfully Represent the Genetic Diversity and Cellular Architecture of Human Acute Myeloid Leukemia
Eirini Papapetrou, et al.
Li Fraumeni Syndrome-Associated Dimer-Forming Mutant p53 Promotes Transactivation-Independent Mitochondrial Cell Death
Carol Prives, et al.
RAB27B Drives a Cancer Stem Cell Phenotype in NSCLC Cells Through Enhanced Extracellular Vesicle Secretion
Verline Justilien, et al.
Comparative Tumor Microenvironment Analysis of Primary and Recurrent Ovarian Granulosa Cell Tumors
R. Tyler Hillman, et al.
Preclinical Evaluation of ON203, A Novel Bioengineered mAb Targeting Oxidized Macrophage Migration Inhibitory Factor as an Anticancer Therapeutic
Alexander Schinagl, et al.
Co-mutations and KRAS G12C inhibitor efficacy in advanced NSCLC
Ferdinandos Skoulidis, et al.
Tuesday, April 18, 2023
The polyamine-hypusine circuit controls an oncogenic translational program essential for malignant conversion in MYC-driven lymphoma
John Cleveland, et al.
T Cells Expressing a Modified FcγRI Exert Antibody-Dependent Cytotoxicity and Overcome the Limitations of CAR T-cell Therapy against Solid Tumors
Yaron Carmi, et al.
Genetic Associations with Smoking Relapse and Proportion of Follow-up in Smoking Relapse throughout Adulthood in Pre- and Postmenopausal Women
Stephanie Jones, et al.
Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950
Fumiyoshi Okano, et al.
Targeting RET Solvent-Front Mutants with Alkynyl Nicotinamide-Based Inhibitors
Ujjwol Khatri, et al.
Activating an Adaptive Immune Response with a Telomerase-mediated Telomere Targeting Therapeutic in Hepatocellular Carcinoma
Jerry Shay, et al.
N-of-1 Trials in Cancer Drug Development
Vivek Subbiah, et al.
Prevalence and Prognostic Significance of Malnutrition in Patients with Brain Metastasis
Fang Fang, et al.
Risk Factors and Trends for HPV-Associated Subsequent Malignant Neoplasms among Adolescent and Young Adult Cancer Survivors
Judy Y Ou, et al.
TONSL Is an Immortalizing Oncogene and a Therapeutic Target in Breast Cancer
Harikrishna Nakshatri, et al.
Spatially Resolved Transcriptomics Deconvolutes Prognostic Histological Subgroups in Patients with Colorectal Cancer and Synchronous Liver Metastases
Nigel B. Jamieson, et al.
Kinome reprogramming is a targetable vulnerability in ESR1 fusion-driven breast cancer
Charles Foulds, et al.
Integrating Tumor-Intrinsic and Immunological Factors to Identify Immunogenic Breast Cancers from a Low-Risk Cohort: Results from the Randomized SweBCG91RT Trial
Axel Stenmark Tullberg, et al.
Dynamics of Sequence and Structural Cell-Free DNA Landscapes in Small-Cell Lung Cancer
Valsamo Anagnostou, et al.
Duvelisib Eliminates CLL B Cells, Impairs CLL-Supporting Cells, and Overcomes Ibrutinib Resistance in a Xenograft Model
Shih-Shih Chen, et al.
Patterns of Oncogene Coexpression at Single-Cell Resolution Influence Survival in Lymphoma
Anand D. Jeyasekharan, et al.
Wednesday, April 19, 2023
BCA101 is a Tumor-Targeted Bifunctional Fusion Antibody that Simultaneously Inhibits EGFR and TGF-ß Signalling to Durably Suppress Tumor Growth
Pradip Nair, et al.
Adaptive c-Met-PLXDC2 Signaling Axis Mediates Cancer Stem Cell Plasticity to Confer Radioresistance-associated Aggressiveness in Head and Neck Cancer
Yong Teng, et al.