AACR Annual Meeting 2024:
AACR Journals’ Concurrent Publications
The AACR journal articles below published concurrently with presentations during the AACR Annual Meeting 2024.
Saturday, April 6, 2024
Integration of Pan-Cancer Cell Line and Single-Cell Transcriptomic Profiles Enables Inference of Therapeutic Vulnerabilities in Heterogeneous Tumors
R. Stephanie Huang, et al.
Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer
Charlie Swanton, et al.
Sunday, April 7, 2024
CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
Sumanta Pal, et al.
Q&A: Owen Witte on Translational Research in Cancer
Dave Gennert, et al.
Monday, April 8, 2024
Randomized Placebo-Controlled, Biomarker-Stratified Phase 1b Microbiome Modulation in Melanoma: Impact of Antibiotic Pre-Conditioning on Microbiome and Immunity
Jennifer Wargo, et al.
The Pan-RAF-MEK Non-Degrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS-MAPK Pathway with Activity Across Diverse RAS- and RAF-Driven Cancers
Margit Hagel, et al.
Insights and Opportunity Costs in Applying Spatial Biology to Study the Tumor Microenvironment
Michael Angelo, et al.
Efficacy and Safety of Adagrasib plus Cetuximab in Patients with KRASG12C-Mutated Metastatic Colorectal Cancer
Natalia Uboha , et al.
PVRL2 Suppresses Antitumor Immunity Through PVRIG- and TIGIT-Independent Pathways
Robert Blelloch, et al.
Integrin αvβ3 Upregulation in Response to Nutrient Stress Promotes Lung Cancer Cell Metabolic Plasticity
David Cheresh, et al.
Ketogenic Diet Alters the Epigenetic and Immune Landscape of Prostate Cancer to Overcome Resistance to Immune Checkpoint Blockade Therapy
Xin Lu, et al.
Comprehensive Transcriptomic Analysis of EWSR1::WT1 Targets Identifies CDK4/6 Inhibitors as an Effective Therapy for Desmoplastic Small Round Cell Tumors
Sean Lee, et al.
Low Exposures to Amphibole or Serpentine Asbestos in Germline Bap1-Mutant Mice Induce Mesothelioma Characterized by an Immunosuppressive Tumor Microenvironment
Joseph R. Testa, et al.
Actívatexto: Feasibility and Acceptability of a Mobile Intervention That Promotes Smoking Cessation and Physical Activity Among Latinos
Francisco Cartujano-Barrera, et al.
A Novel Dual ATM/DNA-PK Inhibitor, XRD-0394, Potently Radiosensitizes and Potentiates PARP and Topoisomerase I Inhibitors
Tona Gilmer, et al.
Impact of Circulating Tumor Cell-Expressed Prostate Specific Membrane Antigen and Prostate-Specific Antigen Transcripts in Different Stages of Prostate Cancer
Jae-Seung Chung, et al.
Transfer Learning Reveals Cancer-Associated Fibroblasts are Associated with Epithelial-Mesenchymal Transition and Inflammation in Cancer Cells in Pancreatic Ductal Adenocarcinoma
Jacquelyn W. Zimmerman, et al.
Oncogene-Driven Non-Small Cell Lung Cancers in Patients with a History of Smoking Lack Smoking-Induced Mutations
Steven Rozen, et al.
Tuesday, April 9, 2024
ZNF397 Deficiency Triggers TET2-driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer
Yaru Xu, et al.
St. Jude Survivorship Portal: Sharing and Analyzing Large Clinical and Genomic Datasets from Pediatric Cancer Survivors
Xin Zhou, et al.
Therapeutic Responses to the RAS-GTP Inhibitor RMC-6236 in RAS-Driven Cancers
Mallika Singh, et al.
Metabolic Signaling in Cancer Metastasis
Sarah-Maria Fendt, et al.
Unleashing Natural IL18 Activity Using an Anti-IL18BP Blocker Induces Potent Immune Stimulation and Antitumor Effects
Eran Ophir, et al.
MILIP Binding to Transfer RNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer
Xu Dong Zhang, et al.
Inhibition of NEK2 promotes chemosensitivity and reduces primary effusion lymphoma burden
Blossom Damania, et al.
Artificial Intelligence Assisted Cancer Status Detection in Radiology Reports
Ankur Arya, et al.
Overcoming Xenoantigen Immunity to Enable Cellular Tracking and Gene Regulation with Immune-Competent “NoGlow” Mice
Zachary Hartman, et al.
Discovery of a Long Half-life AURKA Inhibitor to Treat MYC-amplified Solid Tumors as a Monotherapy and in Combination with Everolimus
Ya-hui Chi, et al.
Proton FLASH Radiotherapy Ameliorates Radiation-induced Salivary Gland Dysfunction and Oral Mucositis and Increases Survival in a Mouse Model of Head and Neck Cancer
Constantinos Koumenis, et al.
CB307: A Dual Targeting Costimulatory Humabody Therapeutic for Treating PSMA-Positive Tumours
Andrew Pierce, et al.
Nicotinamide in Combination with EGFR-TKIs for the Treatment of Stage IV Lung Adenocarcinoma with EGFR Mutations: A Randomized Double-Blind (Phase IIb) Trial
Young-Chul Kim, et al.
Preclinical Development of CAR T Cells with Antigen-Inducible IL-18 Enforcement to Treat GD2-Positive Solid Cancers
Claudia Rossig, et al.
Randomized Phase II Trial of Imiquimod with or without 9-Valent HPV Vaccine vs Observation in Patients with High-Grade Pre-neoplastic Cervical Lesions (NCT02864147)
Alessandro Santin, et al.
Targeting SMAD3 Improves Response to Oxaliplatin in Esophageal Adenocarcinoma Models by Impeding DNA Repair
Wael El-Rifai, et al.
Wednesday, April 10, 2024
A Real-world Toxicity-Atlas Shows that Adverse Events of Combination-therapies Commonly Result in Additive Interactions
Bart Westerman, et al.
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