Blood Cancer Discovery

Immune Surveillance of Acute Myeloid Leukemia Is Mediated by HLA-Presented Antigens on Leukemia Progenitor Cells
Annika Nelde, et al.
Blood Cancer Discovery December 2023

Cancer Discovery

Spatial and Temporal Mapping of Breast Cancer Lung Metastases Identify TREM2 Macrophages as Regulators of the Metastatic Boundary
Ido Yofe, et al.
Cancer Discov December 2023

Cancer Epidemiology, Biomarkers & Prevention

Birth Defects in Offspring of Adolescent and Young Adults with a History of Cancer: A Population-Based Study of 27,000 Women
Caitlin C. Murphy, et al.
Cancer Epidemiol Bio Prev December 2023

Cancer Immunology Research

A Metabolic Gene Survey Pinpoints Fucosylation as a Key Pathway Underlying the Suppressive Function of Regulatory T Cells in Cancer
Sotiria Pinioti, et al.
Cancer Immunol Res December 2023

Cancer Prevention Research

Clinical Performance of hrHPV Primary Screening Using Vaginal versus Cervical Samples to Detect High-grade Intraepithelial Lesions
Jonathan King, et al.
Cancer Prev Res December 2023

Cancer Research

Combinatorial Treatment with PARP and MAPK Inhibitors Overcomes Phenotype Switch-Driven Drug Resistance in Advanced Melanoma
Lorenza P. Ferretti, et al.
Cancer Res December 2023

Genome-Wide CRISPR Screens Identify Multiple Synthetic Lethal Targets That Enhance KRAS^G12C Inhibitor Efficacy
Suman Mukhopadhyay, et al.
Cancer Res December 2023

Clinical Cancer Research

Efficacy of Nivolumab in Pediatric Cancers with High Mutation Burden and Mismatch Repair Deficiency
Anirban Das, et al.
Clin Cancer Res December 2023

Safety and Efficacy of Tucatinib, Letrozole, and Palbociclib in Patients with Previously Treated HR+/HER2+ Breast Cancer
Elena Shagisultanova, et al.
Clin Cancer Res December 2023

Molecular Cancer Research

AMPK Associates with Chromatin and Phosphorylates the TAF-1 Subunit of the Transcription Initiation Complex to Regulate Histone Gene Expression in ALL Cells
Guangyan Sun; Guy J. Leclerc; Sanjay Chahar; Julio C. Barredo
Mol Cancer Res December 2023

Molecular Cancer Therapeutics

Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition
Satish Kumar R. Noonepalle, et al.
Mol Cancer Ther December 2023

Cancer Research Communications

Ultra-Deep Sequencing Reveals the Mutational Landscape of Classical Hodgkin Lymphoma
Felicia Gomez, et al.
Cancer Res Commun December 2023

Blood Cancer Discovery

IVIg Use Associated with Ten-Fold Reduction of Serious Infections in Multiple Myeloma Patients Treated with Anti-BCMA Bispecific Antibodies
Guido Lancman, et al.
Blood Cancer Discovery November 2023

Cancer Discovery

BCL2 Inhibition Reveals a Dendritic Cell–Specific Immune Checkpoint That Controls Tumor Immunosurveillance
Liwei Zhao, et al.
Cancer Discov November 2023

Cancer Epidemiology, Biomarkers & Prevention

Long-term Cancer Survival Trends by Updated Summary Stage
Gonçalo Forjaz, et al.
Cancer Epidemiol Bio Prev November 2023

Cancer Immunology Research

VISTA Expression on Cancer-Associated Endothelium Selectively Prevents T-cell Extravasation
Sietse J. Luk, et al.
Cancer Immunol Res November 2023

Cancer Prevention Research

Methylated DNA Markers for Sporadic Colorectal and Endometrial Cancer Are Strongly Associated with Lynch Syndrome Cancers
Rachel M. Bramblet, et al.
Cancer Prev Res November 2023

Cancer Research

Fasting-Mimicking Diet Drives Antitumor Immunity against Colorectal Cancer by Reducing IgA-Producing Cells
Ziwen Zhong, et al.
Cancer Res November 2023

Stroma-mediated breast cancer cell proliferation indirectly drives chemoresistance by accelerating tumor recovery between chemotherapy cycles
Daria Miroshnychenko, et al.
Cancer Res November 2023

Clinical Cancer Research

Regorafenib plus Vincristine and Irinotecan in Pediatric Patients with Recurrent/Refractory Solid Tumors: An Innovative Therapy for Children with Cancer Study
Michela Casanova, et al.
Clin Cancer Res November 2023

A Phase II Trial of Rivoceranib, an Oral Vascular Endothelial Growth Factor Receptor 2 Inhibitor, for Recurrent or Metastatic Adenoid Cystic Carcinoma
Glenn J. Hanna, et al.
Clin Cancer Res November 2023

Molecular Cancer Research

USP1 Expression Driven by EWS::FLI1 Transcription Factor Stabilizes Survivin and Mitigates Replication Stress in Ewing Sarcoma
Halle J. Mallard , et al.
Mol Cancer Res November 2023

Molecular Cancer Therapeutics

Preclinical Development of Brain Permeable ERβ Agonist for the Treatment of Glioblastoma
Uday P. Pratap, et al.
Mol Cancer Ther November 2023

Cancer Research Communications

Integrated Molecular Characterization of Intraductal Papillary Mucinous Neoplasms: An NCI Cancer Moonshot Precancer Atlas Pilot Project
Alexander Semaan, et al.
Cancer Res Commun November 2023

Blood Cancer Discovery

A Single-Cell Taxonomy Predicts Inflammatory Niche Remodeling to Drive Tissue Failure and Outcome in Human AML
Lanpeng Chen, et al.
Blood Cancer Discovery October 2023

Cancer Discovery

GABA Regulates Electrical Activity and Tumor Initiation in Melanoma
Mohita Tagore, et al.
Cancer Discov October 2023

Cancer Epidemiology, Biomarkers & Prevention

Changes in Geographic Variation and Socioeconomic Inequalities in Esophageal Cancer Mortality in China, 1973–2017
Xianhui Ran, et al.
Cancer Epidemiol Bio Prev October 2023

Cancer Immunology Research

Glioblastoma Vascular Plasticity Limits Effector T-cell Infiltration and Is Blocked by cAMP Activation
Zixi Qin, et al.
Cancer Immunol Res October 2023

Cancer Prevention Research

Examining the Barriers and Opportunities for Human Papillomavirus Vaccine Delivery in Cancer Care Settings: A Mixed-Methods Study
Melany A. Garcia, et al.
Cancer Prev Res October 2023

Cancer Research

Kinome Reprogramming Is a Targetable Vulnerability in ESR1 Fusion-Driven Breast Cancer
Xuxu Gou, et al.
Cancer Res October 2023

Fatty Acids Support the Fitness and Functionality of Tumor-Resident CD8⁺ T Cells by Maintaining SCML4 Expression
Maoxiao Feng, et al.
Cancer Res October 2023

Clinical Cancer Research

A Phase II Study of Optimized Individualized Adaptive Radiotherapy for Hepatocellular Carcinoma
Daniel J. Herr, et al.
Clin Cancer Res October 2023

Efficacy and Safety of Stereotactic Body Radiotherapy Combined with Camrelizumab and Apatinib in Patients with Hepatocellular Carcinoma with Portal Vein Tumor Thrombus
Yue Hu, et al.
Clin Cancer Res October 2023

Molecular Cancer Research

Allele-Specific Gene Regulation, Phenotypes, and Therapeutic Vulnerabilities in Estrogen Receptor Alpha–Mutant Endometrial Cancer
Zannel Blanchard, et al.
Mol Cancer Res October 2023

Molecular Cancer Therapeutics

Dual Targeting of the PDZ1 and PDZ2 Domains of MDA-9/Syntenin Inhibits Melanoma Metastasis
Anjan K. Pradhan, et al.
Mol Cancer Ther October 2023

Cancer Research Communications

A Druggable FOXA1-Glucocorticoid Receptor Transcriptional Axis Drives Tumor Growth in a Subset of Non-Small Cell Lung Cancer
M. Dorso, et al.
Cancer Res Commun October 2023

Blood Cancer Discovery

Time-Dependent Prognostic Value of Serological and Measurable Residual Disease Assessments after Idecabtagene Vicleucel
Bruno Paiva, et al.
Blood Cancer Discovery September 2023

Cancer Discovery

A Novel Autologous CAR-T Therapy, YTB323, with Preserved T-cell Stemness Shows Enhanced CAR T-cell Efficacy in Preclinical and Early Clinical Development
Michael J. Dickinson, et al.
Cancer Discov September 2023

Cancer Epidemiology, Biomarkers & Prevention

Elevated EVL Methylation Level in the Normal Colon Mucosa Is a Potential Risk Biomarker for Developing Recurrent Adenomas
Ming Yu, et al.
Cancer Epidemiol Bio Prev September 2023

Cancer Immunology Research

Aerobic Exercise Alters the Melanoma Microenvironment and Modulates ERK5 S496 Phosphorylation
Hannah Savage, et al.
Cancer Immunol Res September 2023

Cancer Prevention Research

Risk Factors for Early-onset Sporadic Colorectal Cancer in Male Veterans
Thomas F. Imperiale, et al.
Cancer Prev Res September 2023

Cancer Research

Activation of the cGAS/STING Axis in Genome-Damaged Hematopoietic Cells Does Not Impact Blood Cell Formation or Leukemogenesis
Nicole Dressel, et al.
Cancer Res September 2023

Intratumoral Microbiota Composition Regulates Chemoimmunotherapy Response in Esophageal Squamous Cell Carcinoma
Hong Wu, et al.
Cancer Res September 2023

Clinical Cancer Research

Efficacy and Quality-of-Life Following Involved Nodal Radiotherapy for Head and Neck Squamous Cell Carcinoma: The INRT-AIR Phase II Clinical Trial
David J. Sher, et al.
Clin Cancer Res September 2023

CD49d Expression Identifies a Biologically Distinct Subtype of Chronic Lymphocytic Leukemia with Inferior Progression-Free Survival on BTK Inhibitor Therapy
Anfal Alsadhan, et al.
Clin Cancer Res September 2023

Molecular Cancer Research

Identification of a ΔNp63-Dependent Basal-Like A Subtype-Specific Transcribed Enhancer Program (B-STEP) in Aggressive Pancreatic Ductal Adenocarcinoma
Xin Wang , et al.
Mol Cancer Res September 2023

Molecular Cancer Therapeutics

Discovery and Preclinical Characterization of XMT-1660, an Optimized B7-H4-Targeted Antibody–Drug Conjugate for the Treatment of Cancer
Dorin Toader, et al.
Mol Cancer Ther September 2023

Cancer Research Communications

Targeted Single-cell Isolation of Spontaneously Escaping Live Melanoma Cells for Comparative Transcriptomics
Jacqueline L.E. Tearle, et al.
Cancer Res Commun September 2023

Blood Cancer Discovery

A Phase Ib/II Study of Ivosidenib with Venetoclax ± Azacitidine in IDH1-Mutated Myeloid Malignancies
Curtis A. Lachowiez, et al.
Blood Cancer Discovery July 2023

Cancer Discovery

SHP2 Inhibition Sensitizes Diverse Oncogene-Addicted Solid Tumors to Re-treatment with Targeted Therapy
Alexander Drilon, et al.
Cancer Discov August 2023

Cancer Epidemiology, Biomarkers & Prevention

Incidence and Mortality Rates for Childhood Acute Lymphoblastic Leukemia in Puerto Rican Hispanics, 2012–2016
Ingrid M. Montes-Rodríguez, et al.
Cancer Epidemiol Bio Prev August 2023

Cancer Immunology Research

Systemic Alterations in Type-2 Conventional Dendritic Cells Lead to Impaired Tumor Immunity in Pancreatic Cancer
C. Alston James, et al.
Cancer Immunol Res August 2023

Cancer Prevention Research

Progressive Spreading of DNA Methylation in the GSTP1 Promoter CpG Island across Transitions from Precursors to Invasive Prostate Cancer
Harshath Gupta, et al.
Cancer Prev Res August 2023

Cancer Research

BRCA1 Insufficiency Induces a Hypersialylated Acidic Tumor Microenvironment That Promotes Metastasis and Immunotherapy Resistance
Xiaodong Shu, et al.
Cancer Res August 2023

Tumor-Derived Small Extracellular Vesicles Inhibit the Efficacy of CAR T Cells against Solid Tumors
Wenqun Zhong, et al.
Cancer Res August 2023

Clinical Cancer Research

Antitumor Efficacy of the Novel KIT Inhibitor IDRX-42 (Formerly M4205) in Patient- and Cell Line–Derived Xenograft Models of Gastrointestinal Stromal Tumor (GIST)
Luna De Sutter, et al.
Clin Cancer Res August 2023

Osimertinib and Selpercatinib Efficacy, Safety, and Resistance in a Multicenter, Prospectively Treated Cohort of EGFR-Mutant and RET Fusion-Positive Lung Cancers
Julia Rotow, et al.
Clin Cancer Res August 2023

Molecular Cancer Research

Dynamic Intestinal Stem Cell Plasticity and Lineage Remodeling by a Nutritional Environment Relevant to Human Risk for Tumorigenesis
Jiahn Choi, et al.
Mol Cancer Res August 2023

Molecular Cancer Therapeutics

ABBV-184: A Novel Survivin-specific TCR/CD3 Bispecific T-cell Engager is Active against Both Solid Tumor and Hematologic Malignancies
Adam S. Chervin, et al.
Mol Cancer Ther August 2023

Cancer Research Communications

The African-centric P47S Variant of TP53 Confers Immune Dysregulation and Impaired Response to Immune Checkpoint Inhibition
David C. Stieg, et al.
Cancer Res Commun July 2023

Blood Cancer Discovery

The Polyamine–Hypusine Circuit Controls an Oncogenic Translational Program Essential for Malignant Conversion in MYC-Driven Lymphoma
Shima Nakanishi, et al.
Blood Cancer Discovery July 2023

Cancer Discovery

Splicing Factor SRSF1 Promotes Pancreatitis and KRAS^G12D-Mediated Pancreatic Cancer
Ledong Wan, et al.
Cancer Discov July 2023

Cancer Epidemiology, Biomarkers & Prevention

Circadian Disruption and Colorectal Cancer Incidence in Black Women
Lauren E. Barber , et al.
Cancer Epidemiol Bio Prev July 2023

Cancer Immunology Research

High Expression of MHC Class I Overcomes Cancer Immunotherapy Resistance Due to IFNγ Signaling Pathway Defects
Katsushige Kawase, et al.
Cancer Immunol Res July 2023

Cancer Prevention Research

Associations between Physical Activity and Incidence of Cancer among Overweight Adults in Korea: Results from the Health Examinees-G Study
Jaesung Choi, et al.
Cancer Prev Res July 2023

Cancer Research

Periostin⁺ Stromal Cells Guide Lymphovascular Invasion by Cancer Cells
Jamie L. Null, et al.
Cancer Res July 2023

ONC201 in Combination with Paxalisib for the Treatment of H3K27-Altered Diffuse Midline Glioma
Evangeline R. Jackson, et al.
Cancer Res July 2023

Clinical Cancer Research

Devimistat in Combination with Gemcitabine and Cisplatin in Biliary Tract Cancer: Preclinical Evaluation and Phase Ib Multicenter Clinical Trial (BilT-04)
Arathi Mohan, et al.
Clin Cancer Res July 2023

Plasma 25-Hydroxyvitamin D Levels and Survival in Stage III Colon Cancer: Findings from CALGB/SWOG 80702 (Alliance)
Qiao-Li Wang, et al.
Clin Cancer Res July 2023

Molecular Cancer Research

Disruption of the MYC Superenhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia
William M. Yashar, et al.
Mol Cancer Res July 2023

Molecular Cancer Therapeutics

Arginase 1/2 Inhibitor OATD-02: From Discovery to First-in-man Setup in Cancer Immunotherapy
Bartlomiej Borek, et al.
Mol Cancer Ther July 2023

Cancer Research Communications

Multi-institutional Prognostic Modeling in Head and Neck Cancer: Evaluating Impact and Generalizability of Deep Learning and Radiomics
Michal Kazmierski, et al.
Cancer Res Commun June 2023

Blood Cancer Discovery

Molecular Evolution of Classic Hodgkin Lymphoma Revealed Through Whole-Genome Sequencing of Hodgkin and Reed Sternberg Cells
Francesco Maura, et al.
Blood Cancer Discovery June 2023

Cancer Discovery

Late-Stage Metastatic Melanoma Emerges through a Diversity of Evolutionary Pathways
Lavinia Spain, et al.
Cancer Discov June 2023

Cancer Epidemiology, Biomarkers & Prevention

Efficacy of the Outsmart HPV Intervention: A Randomized Controlled Trial to Increase HPV Vaccination among Young Gay, Bisexual, and Other Men Who Have Sex with Men
Paul L. Reiter, et al.
Cancer Epidemiol Bio Prev June 2023

Cancer Immunology Research

Regional Variation in the Tumor Microenvironment, Immune Escape and Prognostic Factors in Breast Cancer in Sub-Saharan Africa
Marcus Bauer, et al.
Cancer Immunol Res June 2023

Cancer Prevention Research

Metabolomic, DNA Methylomic, and Transcriptomic Profiling of Suberoylanilide Hydroxamic Acid Effects on LPS-Exposed Lung Epithelial Cells
Pochung Jordan Chou, et al.
Cancer Prev Res June 2023

Cancer Research

ANO1 Reprograms Cholesterol Metabolism and the Tumor Microenvironment to Promote Cancer Metastasis
Chun-Miao Deng, et al.
Cancer Res June 2023

Angiopoietin-2–Dependent Spatial Vascular Destabilization Promotes T-cell Exclusion and Limits Immunotherapy in Melanoma
Ha-Ram Park, et al.
Cancer Res June 2023

Clinical Cancer Research

Multicenter Phase I Trial of Ivosidenib as Maintenance Treatment Following Allogeneic Hematopoietic Cell Transplantation for IDH1-Mutated Acute Myeloid Leukemia
Amir T. Fathi, et al.
Clin Cancer Res June 2023

Eganelisib, a First-in-Class PI3Kγ Inhibitor, in Patients with Advanced Solid Tumors: Results of the Phase 1/1b MARIO-1 Trial
David S. Hong, et al.
Clin Cancer Res June 2023

Molecular Cancer Research

Interdependence of SS18-SSX–driven YAP1 and β-Catenin Activation in Synovial Sarcoma
Ilka Isfort, et al.
Mol Cancer Res June 2023

Molecular Cancer Therapeutics

Targeting Glutamine Metabolism with a Novel Na⁺/K⁺-ATPase Inhibitor RX108 in Hepatocellular Carcinoma
Daoyan Wei, et al.
Mol Cancer Ther June 2023

Cancer Research Communications

Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome
Vallijah Subasri, et al.
Cancer Res Commun May 2023

Blood Cancer Discovery

METTL3-Mediated m⁶A Modification Controls Splicing Factor Abundance and Contributes to Aggressive CLL
Yiming Wu, et al.
Blood Cancer Discovery May 2023

Cancer Discovery

Opportunities for Achieving the Cancer Moonshot Goal of a 50% Reduction in Cancer Mortality by 2047
Meredith S. Shiels, et al.
Cancer Discov May 2023

Cancer Epidemiology, Biomarkers & Prevention

Risk and Protective Factors for Cancer Mortality among United States Service Members and Veterans (2001–2018)
Neika Sharifian, et al.
Cancer Epidemiol Bio Prev May 2023

Cancer Immunology Research

Low TCR Binding Strength Results in Increased Progenitor-like CD8+ Tumor-Infiltrating Lymphocytes
Zachary L.Z. Hay, et al.
Cancer Immunol Res May 2023

Cancer Prevention Research

Stressful Life Events, Social Support, and Incident Breast Cancer by Estrogen Receptor Status
Wayne R. Lawrence, et al.
Cancer Prev Res May 2023

Cancer Research

Spatial Transcriptomics Depict Ligand–Receptor Cross-talk Heterogeneity at the Tumor-Stroma Interface in Long-Term Ovarian Cancer Survivors
Sammy Ferri-Borgogno, et al.
Cancer Res May 2023

Hypoxia Potentiates the Inflammatory Fibroblast Phenotype Promoted by Pancreatic Cancer Cell–Derived Cytokines
Simon Schwörer, et al.
Cancer Res May 2023

Clinical Cancer Research

Genomic Complexity Predicts Resistance to Endocrine Therapy and CDK4/6 Inhibition in Hormone Receptor–Positive (HR+)/HER2-Negative Metastatic Breast Cancer
Andrew A. Davis, et al.
Clin Cancer Res May 2023

Randomized Trial of Tepotinib Plus Gefitinib versus Chemotherapy in EGFR-Mutant NSCLC with EGFR Inhibitor Resistance Due to MET Amplification: INSIGHT Final Analysis
Chong Kin Liam, et al.
Clin Cancer Res May 2023

Molecular Cancer Research

The Elongin BC Complex Negatively Regulates AXL and Marks a Differentiated Phenotype in Melanoma
Sebastiaan M. Schieven, et al.
Mol Cancer Res May 2023

Molecular Cancer Therapeutics

Preclinical Evaluation of ON203, A Novel Bioengineered mAb Targeting Oxidized Macrophage Migration Inhibitory Factor as an Anticancer Therapeutic
Gregor Rossmueller, et al.
Mol Cancer Ther May 2023

Cancer Research Communications

IOA-244 is a Non–ATP-competitive, Highly Selective, Tolerable PI3K Delta Inhibitor That Targets Solid Tumors and Breaks Immune Tolerance
Zoë Johnson, et al.
Cancer Res Commun April 2023

Blood Cancer Discovery

Anti-BCMA/CD19 CAR T Cells with Early Immunomodulatory Maintenance for Multiple Myeloma Responding to Initial or Later-Line Therapy
Alfred L. Garfall, et al.
Blood Cancer Discovery April 2023

Cancer Discovery

Targeting Microglial Metabolic Rewiring Synergizes with Immune-Checkpoint Blockade Therapy for Glioblastoma
Zengpanpan Ye, et al.
Cancer Discov April 2023

Cancer Epidemiology, Biomarkers & Prevention

The Intersectionality between Race, Ethnicity, and Residential-Level Socioeconomic Status in Disparities of Head and Neck Cancer Outcomes: A SEER Study
Shama D. Karanth, et al.
Cancer Epidemiol Bio Prev April 2023

Cancer Immunology Research

IL18 Receptor Signaling Regulates Tumor-Reactive CD8+ T-cell Exhaustion via Activation of the IL2/STAT5/mTOR Pathway in a Pancreatic Cancer Model
Veronika Lutz, et al.
Cancer Immunol Res April 2023

Cancer Prevention Research

Safety Run-in of Intramuscular pNGVL4a-Sig/E7(detox)/HSP70 DNA and TA-CIN Protein Vaccination as Treatment for HPV16+ ASC-US, ASC-H, or LSIL/CIN1
Mark H. Einstein, et al.
Cancer Prev Res April 2023

Cancer Research

CD73-Dependent Adenosine Signaling through Adora2b Drives Immunosuppression in Ductal Pancreatic Cancer
Erika Y. Faraoni, et al.
Cancer Res April 2023

Active Remodeling of Capillary Endothelium via Cancer Cell–Derived MMP9 Promotes Metastatic Brain Colonization
Matthia A. Karreman, et al.
Cancer Res April 2023

Clinical Cancer Research

Randomized Phase II Trial of Sunitinib or Cediranib in Alveolar Soft Part Sarcoma
James Nguyen, et al.
Clin Cancer Res April 2023

The Oral PI3Kδ Inhibitor Linperlisib for the Treatment of Relapsed and/or Refractory Follicular Lymphoma: A Phase II, Single-Arm, Open-Label Clinical Trial
Tingyu Wang, et al.
Clin Cancer Res April 2023

Molecular Cancer Research

Multi-substrate Metabolic Tracing Reveals Marked Heterogeneity and Dependency on Fatty Acid Metabolism in Human Prostate Cancer
Gio Fidelito, et al.
Mol Cancer Res April 2023

Molecular Cancer Therapeutics

SGN-CD228A Is an Investigational CD228-Directed Antibody–Drug Conjugate with Potent Antitumor Activity across a Wide Spectrum of Preclinical Solid Tumor Models
Rebecca Mazahreh, et al.
Mol Cancer Ther April 2023

Cancer Research Communications

Regulation of Prostate Androgens by Megalin and 25-hydroxyvitamin D Status: Mechanism for High Prostate Androgens in African American Men
Jason Garcia, et al.
Cancer Res Commun March 2023

Blood Cancer Discovery

Adult Low-Hypodiploid Acute Lymphoblastic Leukemia Emerges from Preleukemic TP53-Mutant Clonal Hematopoiesis
Rathana Kim, et al.
Blood Cancer Discovery March 2023

Cancer Discovery

Racial/Ethnic and Sex Differences in Somatic Cancer Gene Mutations among Patients with Early-Onset Colorectal Cancer
Andreana N. Holowatyj, et al.
Cancer Discov March 2023

Cancer Epidemiology, Biomarkers & Prevention

Association of Urinary Biomarkers of Smoking-Related Toxicants with Lung Cancer Incidence in Smokers: The Multiethnic Cohort Study
Shannon S. Cigan, et al.
Cancer Epidemiol Bio Prev March 2023

Cancer Immunology Research

Syntaphilin Regulates Neutrophil Migration in Cancer
Shuyu Fu, et al.
Cancer Immunol Res March 2023

Cancer Prevention Research

Benign Breast Disease, NSAIDs, and Postmenopausal Breast Cancer Risk in the CPS-II Cohort
Mark E. Sherman, et al.
Cancer Prev Res March 2023

Cancer Research

Stromal Reprogramming through Dual PDGFRα/β Blockade Boosts the Efficacy of Anti–PD-1 Immunotherapy in Fibrotic Tumors
Takahiko Akiyama, et al.
Cancer Res March 2023

Olig1/2-Expressing Intermediate Lineage Progenitors Are Predisposed to PTEN/p53-Loss–Induced Gliomagenesis and Harbor Specific Therapeutic Vulnerabilities
Ravinder Verma, et al.
Cancer Res March 2023

Clinical Cancer Research

Beneficial Effects of Mifepristone Treatment in Patients with Breast Cancer Selected by the Progesterone Receptor Isoform Ratio: Results from the MIPRA Trial
Andrés Elía, et al.
Clin Cancer Res March 2023

A Phase Ib/II Trial of Combined BRAF and EGFR Inhibition in BRAF V600E Positive Metastatic Colorectal Cancer and Other Cancers: The EVICT (Erlotinib and Vemurafenib In Combination Trial) Study
Lavinia Tan, et al.
Clin Cancer Res March 2023

Molecular Cancer Research

ATM Regulation of the Cohesin Complex Is Required for Repression of DNA Replication and Transcription in the Vicinity of DNA Double-Strand Breaks
Thomas E. Bass; Donald E. Fleenor; Paige E. Burrell; Michael B. Kastan
Mol Cancer Res March 2023

Molecular Cancer Therapeutics

Interplay Between Extracellular Matrix Remodeling and Angiogenesis in Tumor Ecosystem
Rohit Siddhartha; Minal Garg
Mol Cancer Ther March 2023

Cancer Research Communications

Phase I Trial of Intravenous Mistletoe Extract in Advanced Cancer
Channing J. Paller, et al.
Cancer Res Commun February 2023

Blood Cancer Discovery

Distinct Genetically Determined Origins of Myd88/BCL2-Driven Aggressive Lymphoma Rationalize Targeted Therapeutic Intervention Strategies
Ruth Flümann, et al.
Blood Cancer Discovery January 2023

Cancer Discovery

Efficacy of a Small-Molecule Inhibitor of Kras^G12D in Immunocompetent Models of Pancreatic Cancer
Samantha B. Kemp, et al.
Cancer Discov February 2023

Cancer Epidemiology, Biomarkers & Prevention

Race Differences in Patient-Reported Symptoms during Chemotherapy among Women with Early-Stage Hormone Receptor–Positive Breast Cancer
Xin Hu, et al.
Cancer Epidemiol Bio Prev February 2023

Cancer Immunology Research

Rational Protein Design Yields a CD20 CAR with Superior Antitumor Efficacy Compared with CD19 CAR
Ximin Chen, et al.
Cancer Immunol Res February 2023

Cancer Prevention Research

Plasma Concentrations of Gut Hormones Acyl Ghrelin and Peptide YY and Subsequent Risk of Colorectal Cancer and Molecular Tumor Subtypes
Stina Bodén, et al.
Cancer Prev Res February 2023

Cancer Research

Single-Cell Analysis in Lung Adenocarcinoma Implicates RNA Editing in Cancer Innate Immunity and Patient Prognosis
Tracey W. Chan, et al.
Cancer Res February 2023

The Cytidine Deaminase APOBEC3G Contributes to Cancer Mutagenesis and Clonal Evolution in Bladder Cancer
Weisi Liu, et al.
Cancer Res February 2023

Clinical Cancer Research

Clinical Features Associated with Outcomes and Biomarker Analysis of Dabrafenib plus Trametinib Treatment in Patients with BRAF-Mutant Melanoma Brain Metastases
James S. Wilmott, et al.
Clin Cancer Res February 2023

Five-Year Clinical Outcomes after Neoadjuvant Nivolumab in Resectable Non–Small Cell Lung Cancer
Samuel Rosner, et al.
Clin Cancer Res February 2023

Molecular Cancer Research

BET Inhibitors Target the SCLC-N Subtype of Small-Cell Lung Cancer by Blocking NEUROD1 Transactivation
Haobin Chen, et al.
Mol Cancer Res February 2023

Molecular Cancer Therapeutics

Discovery of STRO-002, a Novel Homogeneous ADC Targeting Folate Receptor Alpha, for the Treatment of Ovarian and Endometrial Cancers
Xiaofan Li, et al.
Mol Cancer Ther February 2023

Cancer Research Communications

Incorporating RNA-based Risk Scores for Genomic Instability to Predict Breast Cancer Recurrence and Immunogenicity in a Diverse Population
Alina M. Hamilton, et al.
Cancer Res Commun January 2023

Blood Cancer Discovery

Extracellular Vesicle Secretion by Leukemia Cells In Vivo Promotes CLL Progression by Hampering Antitumor T-cell Responses
Ernesto Gargiulo, et al.
Blood Cancer Discovery January 2023

Cancer Discovery

Creating MHC-Restricted Neoantigens with Covalent Inhibitors That Can Be Targeted by Immune Therapy
Takamitsu Hattori, et al.
Cancer Discov January 2023

Cancer Epidemiology, Biomarkers & Prevention

Impact and Recovery from COVID-19–Related Disruptions in Colorectal Cancer Screening and Care in the US: A Scenario Analysis
Rosita van den Puttelaar, et al.
Cancer Epidemiol Bio Prev January 2023

Cancer Immunology Research

The Conventional Dendritic Cell 1 Subset Primes CD8+ T Cells and Traffics Tumor Antigen to Drive Antitumor Immunity in the Brain
Jay A. Bowman-Kirigin, et al.
Cancer Immunol Res January 2023

Cancer Prevention Research

Phase I Dose Escalation Study of Topical Bexarotene in Women at High Risk for Breast Cancer
Parijatham S. Thomas, et al.
Cancer Prev Res January 2023

Cancer Research

Spatial Transcriptomic Analysis of a Diverse Patient Cohort Reveals a Conserved Architecture in Triple-Negative Breast Cancer
Rania Bassiouni, et al.
Cancer Res January 2023

Mitochondrial Uncoupling Induces Epigenome Remodeling and Promotes Differentiation in Neuroblastoma
Haowen Jiang, et al.
Cancer Res January 2023

Clinical Cancer Research

Pilot Study of ONCOS-102 and Pembrolizumab: Remodeling of the Tumor Microenvironment and Clinical Outcomes in Anti–PD-1–Resistant Advanced Melanoma
Alexander N. Shoushtari, et al.
Clin Cancer Res January 2023

Intraperitoneal Monocytes plus IFNs as a Novel Cellular Immunotherapy for Ovarian Cancer: Mechanistic Characterization and Results from a Phase I Clinical Trial
Daniel S. Green, et al.
Clin Cancer Res January 2023

Molecular Cancer Research

Mitochondrial Aconitase ACO2 Links Iron Homeostasis with Tumorigenicity in Non–Small Cell Lung Cancer
Shideh Mirhadi, et al.
Mol Cancer Res January 2023

Molecular Cancer Therapeutics

Antibody–Drug Conjugate Sacituzumab Govitecan Drives Efficient Tissue Penetration and Rapid Intracellular Drug Release
Anna Kopp, et al.
Mol Cancer Ther January 2023

Cancer Research Communications

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