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Journal Articles

The Bispecific Tumor Antigen-Conditional 4–1BB x 5T4 Agonist, ALG.APV-527, Mediates Strong T-Cell Activation and Potent Antitumor Activity in Preclinical Studies

Michelle H. Nelson, Sara Fritzell, Robert Miller, Doreen Werchau, Danielle Van Citters, Anneli Nilsson, Lynda Misher, Lill Ljung, Robert Bader, Adnan Deronic, Allison G. Chunyk, Lena Schultz, Laura A. Varas, Nadia Rose, Maria Håkansson, Jane Gross, Christina Furebring, Peter Pavlik, Anette Sundstedt, Niina Veitonmäki, Hilario J. Ramos, Anna Säll, Anna Dahlman, David Bienvenue, Laura von Schantz, Catherine J. McMahan, Maria Askmyr, Gabriela Hernandez-Hoyos, Peter Ellmark
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2023) 22 (1): 89–101.
https://doi.org/10.1158/1535-7163.MCT-22-0395
Published: 03 January 2023
... Sundstedt; Niina Veitonmäki; Hilario J. Ramos; Anna Säll; Anna Dahlman; David Bienvenue; Laura von Schantz; Catherine J. McMahan; Maria Askmyr; Gabriela Hernandez-Hoyos; Peter Ellmark 4–1BB (CD137) is an activation-induced costimulatory receptor that regulates immune responses of activated CD8 T and natural...
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Includes: Supplementary data
Journal Articles

Improving Efficacy and Safety of Agonistic Anti-CD40 Antibody Through Extracellular Matrix Affinity

Jun Ishihara, Ako Ishihara, Lambert Potin, Peyman Hosseinchi, Kazuto Fukunaga, Martina Damo, Thomas F. Gajewski, Melody A. Swartz, Jeffrey A. Hubbell
Journal: Molecular Cancer Therapeutics
Series: Author Choice
Mol Cancer Ther (2018) 17 (11): 2399–2411.
https://doi.org/10.1158/1535-7163.MCT-18-0091
Published: 02 November 2018
... .  Polymeric microparticles for sustained and local delivery of antiCD40 and antiCTLA-4 in immunotherapy of cancer . Biomaterials   2015 ; 61 : 33 – 40 . 18. Sandin   LC , Orlova   A , Gustafsson   E , Ellmark   P , Tolmachev   V , Totterman   TH , et al   Locally delivered CD40...
View article titled, Improving Efficacy and Safety of Agonistic Anti-CD40 Antibody Through Extracellular Matrix Affinity
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Includes: Supplementary data