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Journal Articles

(+)-JJ-74–138 is a Novel Noncompetitive Androgen Receptor Antagonist

Ryan N. Cole, Wei Chen, Laura E. Pascal, Joel B. Nelson, Peter Wipf, Zhou Wang
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2022) 21 (4): 483–492.
https://doi.org/10.1158/1535-7163.MCT-21-0432
Published: 01 April 2022
View article titled, (+)-JJ-74–138 is a Novel Noncompetitive Androgen Receptor Antagonist
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Includes: Supplementary data
Journal Articles

A Novel Small Molecule Targets Androgen Receptor and Its Splice Variants in Castration-Resistant Prostate Cancer

Zhenyu Yang, Dan Wang, James K. Johnson, Laura E. Pascal, Keita Takubo, Raghunandan Avula, Anish Bhaswanth Chakka, Jianhua Zhou, Wei Chen, Mingming Zhong, Qiong Song, Hui Ding, Zeyu Wu, Uma R. Chandran, Taber S. Maskrey, Joel B. Nelson, Peter Wipf, Zhou Wang
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2020) 19 (1): 75–88.
https://doi.org/10.1158/1535-7163.MCT-19-0489
Published: 03 January 2020
View article titled, A Novel Small Molecule Targets Androgen Receptor and Its Splice Variants in Castration-Resistant Prostate Cancer
Open the PDF for A Novel Small Molecule Targets Androgen Receptor and Its Splice Variants in Castration-Resistant Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Hsp70 Binds to the Androgen Receptor N-terminal Domain and Modulates the Receptor Function in Prostate Cancer Cells

Jun Dong, Zeyu Wu, Dan Wang, Laura E. Pascal, Joel B. Nelson, Peter Wipf, Zhou Wang
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (1): 39–50.
https://doi.org/10.1158/1535-7163.MCT-18-0432
Published: 02 January 2019
View article titled, Hsp70 Binds to the Androgen Receptor N-terminal Domain and Modulates the Receptor Function in Prostate Cancer Cells
Open the PDF for Hsp70 Binds to the Androgen Receptor N-terminal Domain and Modulates the Receptor Function in Prostate Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Inhibition of Androgen Receptor Nuclear Localization and Castration-Resistant Prostate Tumor Growth by Pyrroloimidazole-based Small Molecules

Khalid Z. Masoodi, Yadong Xu, Javid A. Dar, Kurtis Eisermann, Laura E. Pascal, Erica Parrinello, Junkui Ai, Paul A. Johnston, Joel B. Nelson, Peter Wipf, Zhou Wang
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2017) 16 (10): 2120–2129.
https://doi.org/10.1158/1535-7163.MCT-17-0176
Published: 02 October 2017
View article titled, Inhibition of Androgen Receptor Nuclear Localization and Castration-Resistant Prostate Tumor Growth by Pyrroloimidazole-based Small Molecules
Open the PDF for Inhibition of Androgen Receptor Nuclear Localization and Castration-Resistant Prostate Tumor Growth by Pyrroloimidazole-based Small Molecules in another window
Journal Articles

Mitochondria-mediated apoptosis by diallyl trisulfide in human prostate cancer cells is associated with generation of reactive oxygen species and regulated by Bax/Bak

Young-Ae Kim, Dong Xiao, Hui Xiao, Anna A. Powolny, Karen L. Lew, Megan L. Reilly, Yan Zeng, Zhou Wang, Shivendra V. Singh
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (5): 1599–1609.
https://doi.org/10.1158/1535-7163.MCT-06-0754
Published: 18 May 2007
View article titled, Mitochondria-mediated apoptosis by diallyl trisulfide in human prostate cancer cells is associated with generation of reactive oxygen species and regulated by Bax/Bak
Open the PDF for Mitochondria-mediated apoptosis by diallyl trisulfide in human prostate cancer cells is associated with generation of reactive oxygen species and regulated by Bax/Bak in another window