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Journal Articles

Differential Distribution of the DNA-PKcs Inhibitor Peposertib Selectively Radiosensitizes Patient-derived Melanoma Brain Metastasis Xenografts

Jianxiong Ji, Sonja Dragojevic, Cameron M. Callaghan, Emily J. Smith, Surabhi Talele, Wenjuan Zhang, Margaret A. Connors, Ann C. Mladek, Zeng Hu, Katrina K. Bakken, Paige P. Sarkaria, Brett L. Carlson, Danielle M. Burgenske, Paul A. Decker, Mohammad Abdur Rashid, Mi-hyeon Jang, Shiv K. Gupta, Jeanette E. Eckel-Passow, William F. Elmquist, Jann N. Sarkaria
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2024) 23 (5): 662–671.
https://doi.org/10.1158/1535-7163.MCT-23-0552
Published: 02 May 2024
View article titled, Differential Distribution of the DNA-PKcs Inhibitor Peposertib Selectively Radiosensitizes Patient-derived Melanoma Brain Metastasis Xenografts
Open the PDF for Differential Distribution of the DNA-PKcs Inhibitor Peposertib Selectively Radiosensitizes Patient-derived Melanoma Brain Metastasis Xenografts in another window
Includes: Supplementary data
Journal Articles

Abstract A148: The radiosensitizing effects of the novel brain penetrant and potent ATM inhibitor WSD0628 in glioblastoma and melanoma patient derived xenografts

Zhiyi Xue, Ann C. Mladek, Sneha Rathi, Danielle M. Burgenske, Shiv K. Gupta, Brett L. Carlson, Zeng Hu, Lauren L Ott, Katrina K. Bakken, Rachael A. Vaubel, William F Elmquist, Wei Zhong, Jann N Sarkaria
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2023) 22 (12_Supplement): A148.
https://doi.org/10.1158/1535-7163.TARG-23-A148
Published: 01 December 2023
View article titled, Abstract A148: The radiosensitizing effects of the novel brain penetrant and potent ATM inhibitor WSD0628 in glioblastoma and melanoma patient derived xenografts
Journal Articles

Abstract A002: The utility of pre-clinical trials in glioblastoma patient-derived xenografts (PDXs) models for informing clinical trial development of therapeutic strategies

Danielle M Burgenske, Ann C Mladek, Katrina K Bakken, Zeng Hu, Brett L Carlson, Paul A Decker, Jeanette E Eckel-Passow, Jann N Sarkaria
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2023) 22 (12_Supplement): A002.
https://doi.org/10.1158/1535-7163.TARG-23-A002
Published: 01 December 2023
View article titled, Abstract A002: The utility of pre-clinical trials in glioblastoma patient-derived xenografts (PDXs) models for informing clinical trial development of therapeutic strategies
Journal Articles

Abstract C051: MDM2 inhibitor KRT-232 extends survival in glioblastoma patient-derived xenograft models

Ann C Mladek, Shiv Gupta, Minjee Kim, Afroz Shareef Mohammad, Katrina K Bakken, Helen He, Zeng Hu, Danielle M Burgenske, Brett L Carlson, William F Elmquist, Jann Sarkaria
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (12_Supplement): C051.
https://doi.org/10.1158/1535-7163.TARG-19-C051
Published: 01 December 2019
View article titled, Abstract C051: MDM2 inhibitor KRT-232 extends survival in glioblastoma patient-derived xenograft models
Journal Articles

Abstract C096: Modeling the clinical paradigm of lisavanbulin (BAL101553) deployment in patient-derived xenografts (PDX) of glioblastoma (GBM)

Danielle M Burgenske, Ann C Mladek, Jenny L Pokorny, Heidi A Lane, Felix Bachmann, Rachael A Vaubel, Mark A Schroeder, Katrina K Bakken, Lihong He, Zeng Hu, Brett L Carlson, Surabhi Talele, Gautham Gampa, Matthew L Kosel, Paul A Decker, Jeanette E Eckel-Passow, William F Elmquist, Jann Sarkaria
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (12_Supplement): C096.
https://doi.org/10.1158/1535-7163.TARG-19-C096
Published: 01 December 2019
View article titled, Abstract C096: Modeling the clinical paradigm of lisavanbulin (BAL101553) deployment in patient-derived xenografts (PDX) of glioblastoma (GBM)