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Journal Articles

Abstract PR010: CDK12 loss promotes prostate cancer development while exposing vulnerabilities to paralog-based synthetic lethality

Jean C. Tien, Yu Chang, Yuping Zhang, Jonathan Chou, Yunhui Cheng, Xiaoju Wang, Jianzhang Yang, Rahul Mannan, Palak Shah, Xiao-Ming Wang, Abbey Todd, Sanjana Eyunni, Caleb Cheng, Xuhong Cao, Yi Bao, James Neiswender, Rachel Brough, Stephen Pettitt, Estefania Labanca, Yuzhuo Wang, Marcin Cieslik, Christopher J. Lord, Ke Ding, Arul M. Chinnaiyan
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2024) 23 (6_Supplement): PR010.
https://doi.org/10.1158/1538-8514.SYNTHLETH24-PR010
Published: 10 June 2024
View article titled, Abstract PR010: <em>CDK12</em> loss promotes prostate cancer development while exposing vulnerabilities to paralog-based synthetic lethality
Journal Articles

Selective Inhibition of the Lactate Transporter MCT4 Reduces Growth of Invasive Bladder Cancer

Tilman Todenhöfer, Roland Seiler, Craig Stewart, Igor Moskalev, Jian Gao, Simroop Ladhar, Alireza Kamjabi, Nader Al Nakouzi, Tetsuharo Hayashi, Stephen Choi, Yuzhuo Wang, Sebastian Frees, Mads Daugaard, Htoo Zarni Oo, Pascale Fisel, Matthias Schwab, Elke Schaeffeler, James Douglas, Jörg Hennenlotter, Jens Bedke, Ewan A. Gibb, Ladan Fazli, Arnulf Stenzl, Peter C. Black
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (12): 2746–2755.
https://doi.org/10.1158/1535-7163.MCT-18-0107
Published: 03 December 2018
View article titled, Selective Inhibition of the Lactate Transporter MCT4 Reduces Growth of Invasive Bladder Cancer
Open the PDF for Selective Inhibition of the Lactate Transporter MCT4 Reduces Growth of Invasive Bladder Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract A150: Anti-BIRC6 antisense oligonucleotide inhibits enzalutamide-resistant castration-resistant prostate cancer growth in patient-derived xenograft model by suppressing multiple signaling pathways

Iris Sze Ue Luk, Raunak Shrestha, Hui Xue, Yuwei Wang, Peter Gout, Colin Collins, Martin Gleave, Yuzhuo Wang
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (12_Supplement_2): A150.
https://doi.org/10.1158/1535-7163.TARG-15-A150
Published: 01 December 2015
View article titled, Abstract A150: Anti-BIRC6 antisense oligonucleotide inhibits enzalutamide-resistant castration-resistant prostate cancer growth in patient-derived xenograft model by suppressing multiple signaling pathways
Journal Articles

Next Generation Sequencing of Prostate Cancer from a Patient Identifies a Deficiency of Methylthioadenosine Phosphorylase, an Exploitable Tumor Target

Colin C. Collins, Stanislav V. Volik, Anna V. Lapuk, Yuwei Wang, Peter W. Gout, Chunxiao Wu, Hui Xue, Hongwei Cheng, Anne Haegert, Robert H. Bell, Sonal Brahmbhatt, Shawn Anderson, Ladan Fazli, Antonio Hurtado-Coll, Mark A. Rubin, Francesca Demichelis, Himisha Beltran, Martin Hirst, Marco Marra, Christopher A. Maher, Arul M. Chinnaiyan, Martin Gleave, Joseph R. Bertino, Martin Lubin, Yuzhuo Wang
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2012) 11 (3): 775–783.
https://doi.org/10.1158/1535-7163.MCT-11-0826
Published: 06 March 2012
View article titled, Next Generation Sequencing of Prostate Cancer from a Patient Identifies a Deficiency of Methylthioadenosine Phosphorylase, an Exploitable Tumor Target
Open the PDF for Next Generation Sequencing of Prostate Cancer from a Patient Identifies a Deficiency of Methylthioadenosine Phosphorylase, an Exploitable Tumor Target in another window
Includes: Supplementary data