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Yuan Chen
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Journal Articles

Acrolein induces exosomal miR-30a-5p/NCAM1 axis promoting glioma progression.

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Hong-Chieh Tsai, Pei-Yu Liu, Zhen-Jie Tong, Chian-You Wu, Ya-Rou Lin, Kuo-Chen Wei, Chiung-Yin Huang, Ko-Ting Chen, Ya-Jui Lin, Pin-Yuan Chen, Hsiang-Tsui Wang
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2025)
https://doi.org/10.1158/1535-7163.MCT-25-0117
Published: 13 June 2025
View articletitled, Acrolein induces exosomal miR-30a-5p/NCAM1 axis promoting glioma progression.
Open the PDF for Acrolein induces exosomal miR-30a-5p/NCAM1 axis promoting glioma progression. in another window
Includes: Supplementary data
Journal Articles

Epigenetic Regulation of Cellular Senescence in Gastrointestinal Cancer

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Ting Ye, Hang Gao, Zheng-rong Zhang, Yang Ge, Yi-ke Liu, Jing-yuan Yan, De-yi Li, Feng-yuan Chen, Hang Song
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther OF1–OF11.
https://doi.org/10.1158/1535-7163.MCT-24-0949
Published: 10 April 2025
View articletitled, Epigenetic Regulation of Cellular Senescence in Gastrointestinal Cancer
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Journal Articles

Inhibition of SUMOylation Induces Adaptive Antitumor Immunity against Pancreatic Cancer through Multiple Effects on the Tumor Microenvironment

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Suna Erdem, Hyojae James Lee, Jayanth Surya Narayanan Shankara Narayanan, Mohottige Don Neranjan Tharuka, Jorge De la Torre, Tianchen Ren, Yixuan Kuang, Tharindumala Abeywardana, Kevin Li, Allison J. Berger, Andrew M. Lowy, Rebekah R. White, Yuan Chen
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2024) 23 (11): 1597–1612.
https://doi.org/10.1158/1535-7163.MCT-23-0572
Published: 04 November 2024
View articletitled, Inhibition of SUMOylation Induces Adaptive Antitumor Immunity against Pancreatic Cancer through Multiple Effects on the Tumor Microenvironment
Open the PDF for Inhibition of SUMOylation Induces Adaptive Antitumor Immunity against Pancreatic Cancer through Multiple Effects on the Tumor Microenvironment in another window
Includes: Supplementary data
Journal Articles

Abstract A59: Exploration of Tid1 and mitochondrial EGFR in non-small cell lung carcinoma tumorgenesis

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Chi-Yuan Chen, Yu-Han Lin, Wen-Chieh Pi
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (12_Supplement_2): A59.
https://doi.org/10.1158/1535-7163.TARG-15-A59
Published: 01 December 2015
View articletitled, Abstract A59: Exploration of Tid1 and mitochondrial EGFR in non-small cell lung carcinoma tumorgenesis
Journal Articles

Abstract A146: Study of anti-leukemia activity of N-(1-pyrenlyl) maleimide in vivo using a bioluminescent mouse model

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Tzu-Chien Wang, Pei-Chi Chang, Chi-Yuan Chen
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (12_Supplement_2): A146.
https://doi.org/10.1158/1535-7163.TARG-15-A146
Published: 01 December 2015
View articletitled, Abstract A146: Study of anti-leukemia activity of N-(1-pyrenlyl) maleimide in vivo using a bioluminescent mouse model
Journal Articles

Abstract B104: Tid1 as a novel target for HSP-directed therapy in NSCLC.

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Chi-Yuan Chen, Chia-Ing Jan, Jeng-Fan Lo, Tse-Ming Hong, Pan-Chyr Yang
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (11_Supplement): B104.
https://doi.org/10.1158/1535-7163.TARG-11-B104
Published: 12 November 2011
View articletitled, Abstract B104: Tid1 as a novel target for HSP-directed therapy in NSCLC.
Journal Articles

SIRT Inhibitors Induce Cell Death and p53 Acetylation through Targeting Both SIRT1 and SIRT2

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Barrie Peck, Chun-Yuan Chen, Ka-Kei Ho, Paolo Di Fruscia, Stephen S. Myatt, R. Charles Coombes, Matthew J. Fuchter, Chwan-Deng Hsiao, Eric W.-F. Lam
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2010) 9 (4): 844–855.
https://doi.org/10.1158/1535-7163.MCT-09-0971
Published: 07 April 2010
View articletitled, SIRT Inhibitors Induce Cell Death and p53 Acetylation through Targeting Both SIRT1 and SIRT2
Open the PDF for SIRT Inhibitors Induce Cell Death and p53 Acetylation through Targeting Both SIRT1 and SIRT2 in another window
Includes: Supplementary data
Journal Articles

SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome

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Xuefei Cao, Carlos Clavijo, Xu Li, H. Helen Lin, Yuan Chen, Hsiu-Ming Shih, David K. Ann
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (4): 923–934.
https://doi.org/10.1158/1535-7163.MCT-07-0540
Published: 15 April 2008
View articletitled, SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome
Open the PDF for SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome in another window
Includes: Supplementary data
Journal Articles

SUMOylation plays a role in gemcitabine- and bortezomib-induced cytotoxicity in human oropharyngeal carcinoma KB gemcitabine-resistant clone

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Vincent Chung, Bingsen Zhou, Xiyong Liu, Lijun Zhu, Lee M. Boo, Ha-Van Nguyen, David K. Ann, Jing Song, Yuan Chen, Yun Yen
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2006) 5 (3): 533–540.
https://doi.org/10.1158/1535-7163.MCT-05-0290
Published: 16 March 2006
View articletitled, SUMOylation plays a role in gemcitabine- and bortezomib-induced cytotoxicity in human oropharyngeal carcinoma KB gemcitabine-resistant clone
Open the PDF for SUMOylation plays a role in gemcitabine- and bortezomib-induced cytotoxicity in human oropharyngeal carcinoma KB gemcitabine-resistant clone in another window