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Journal Articles

Abstract A102: A comparative pharmacokinetic-pharmacodynamic-treatment study of PARP inhibitors demonstrates favorable properties for niraparib activity in preclinical tumor models

Kaiming Sun, Grace Poon, Sarah Wang, Paul Vancutsem, Sridhar Ramaswamy, Jeffrey Hanke, Jing Yu Wang

Mol Cancer Ther (2018) 17 (1_Supplement): A102.

https://doi.org/10.1158/1535-7163.TARG-17-A102

Published: 01 January 2018

View article titled, Abstract A102: A comparative pharmacokinetic-pharmacodynamic-treatment study of PARP inhibitors demonstrates favorable properties for niraparib activity in preclinical tumor models

Journal Articles

Abstract B013: Elevation of immune cell infiltration and interferon-stimulated gene expression is associated with niraparib treatment in murine syngeneic tumor models

Sarah Wang, Kaiming Sun, Yonghong Xiao, Keith Mikule, Sridhar Ramaswamy, Jeffrey Hanke, Jing Yu Wang

Mol Cancer Ther (2018) 17 (1_Supplement): B013.

https://doi.org/10.1158/1535-7163.TARG-17-B013

Published: 01 January 2018

View article titled, Abstract B013: Elevation of immune cell infiltration and interferon-stimulated gene expression is associated with niraparib treatment in murine syngeneic tumor models

Journal Articles

Preclinical Activity of the Novel Anti-Prolactin Receptor (PRLR) Antibody–Drug Conjugate REGN2878-DM1 in PRLR-Positive Breast Cancers

Marcus P. Kelly, Carlos Hickey, Sosina Makonnen, Sandra Coetzee, Sumreen Jalal, Yu Wang, Frank Delfino, Jing Shan, Terra B. Potocky, Ishita Chatterjee, Julian Andreev, Arthur Kunz, Christopher D'Souza, Jason T. Giurleo, Thomas Nittoli, Pamela A. Trail, Gavin Thurston, Jessica R. Kirshner

Mol Cancer Ther (2017) 16 (7): 1299–1311.

https://doi.org/10.1158/1535-7163.MCT-16-0839

Published: 04 July 2017

View article titled, Preclinical Activity of the Novel Anti-Prolactin Receptor (PRLR) Antibody–Drug Conjugate REGN2878-DM1 in PRLR-Positive Breast Cancers

Includes: Supplementary data

Journal Articles

Suppression of the Growth and Invasion of Human Head and Neck Squamous Cell Carcinomas via Regulating STAT3 Signaling and the miR-21/β-catenin Axis with HJC0152

Mol Cancer Ther (2017) 16 (4): 578–590.

https://doi.org/10.1158/1535-7163.MCT-16-0606

Published: 02 April 2017

View article titled, Suppression of the Growth and Invasion of Human Head and Neck Squamous Cell Carcinomas via Regulating STAT3 Signaling and the miR-21/β-catenin Axis with HJC0152

Includes: Supplementary data

Journal Articles

Inhibition of HSP90 by AUY922 Preferentially Kills Mutant KRAS Colon Cancer Cells by Activating Bim through ER Stress

Chun Yan Wang, Su Tang Guo, Jia Yu Wang, Fen Liu, Yuan Yuan Zhang, Hamed Yari, Xu Guang Yan, Lei Jin, Xu Dong Zhang, Chen Chen Jiang

Mol Cancer Ther (2016) 15 (3): 448–459.

https://doi.org/10.1158/1535-7163.MCT-15-0778

Published: 06 March 2016

View article titled, Inhibition of HSP90 by AUY922 Preferentially Kills Mutant <em>KRAS</em> Colon Cancer Cells by Activating Bim through ER Stress

Includes: Supplementary data

Journal Articles

Activation of AR Sensitizes Breast Carcinomas to NVP-BEZ235's Therapeutic Effect Mediated by PTEN and KLLN Upregulation

Yu Wang, Qi Yu, Xin He, Todd Romigh, Jessica Altemus, Charis Eng

Mol Cancer Ther (2014) 13 (2): 517–527.

https://doi.org/10.1158/1535-7163.MCT-13-0655

Published: 09 February 2014

View article titled, Activation of AR Sensitizes Breast Carcinomas to NVP-BEZ235's Therapeutic Effect Mediated by PTEN and KLLN Upregulation

Includes: Supplementary data

Journal Articles

PS-341 and Histone Deacetylase Inhibitor Synergistically Induce Apoptosis in Head and Neck Squamous Cell Carcinoma Cells

JinKoo Kim, Jean Guan, Insoon Chang, Xiaohong Chen, Demin Han, Cun-Yu Wang

Mol Cancer Ther (2010) 9 (7): 1977–1984.

https://doi.org/10.1158/1535-7163.MCT-10-0141

Published: 07 July 2010

View article titled, PS-341 and Histone Deacetylase Inhibitor Synergistically Induce Apoptosis in Head and Neck Squamous Cell Carcinoma Cells

Journal Articles

Interruption of RNA processing machinery by a small compound, 1-[(4-chlorophenyl)methyl]-1H-indole-3-carboxaldehyde (oncrasin-1)

Wei Guo, Shuhong Wu, Li Wang, Rui-yu Wang, Xiaoli Wei, Jinsong Liu, Bingliang Fang

Mol Cancer Ther (2009) 8 (2): 441–448.

https://doi.org/10.1158/1535-7163.MCT-08-0839

Published: 11 February 2009

View article titled, Interruption of RNA processing machinery by a small compound, 1-[(4-chlorophenyl)methyl]-1<em>H</em>-indole-3-carboxaldehyde (oncrasin-1)

Includes: Supplementary data

Journal Articles

Insulin-like growth factor-I receptor blockade by a specific tyrosine kinase inhibitor for human gastrointestinal carcinomas

Wenhua Piao, Yu Wang, Yasushi Adachi, Hiroyuki Yamamoto, Rong Li, Arisa Imsumran, Hua Li, Tadateru Maehata, Masanori Li, Yoshiaki Arimura, Choon-Taek Lee, Yasuhisa Shinomura, David P. Carbone, Kohzoh Imai

Mol Cancer Ther (2008) 7 (6): 1483–1493.

https://doi.org/10.1158/1535-7163.MCT-07-2395

Published: 19 June 2008

View article titled, Insulin-like growth factor-I receptor blockade by a specific tyrosine kinase inhibitor for human gastrointestinal carcinomas

Journal Articles

Osteoblast-induced EGFR/ERBB2 signaling in androgen-sensitive prostate carcinoma cells characterized by multiplex kinase activity profiling

Ase Bratland, Piet Boender, Hanne Hoifodt, Ingrid Ostensen, Rob Ruijtenbeek, Meng-yu Wang, Jens Berg, Wolfgang Lilleby, Oystein Fodstad, Anne Ree

Mol Cancer Ther (2007) 6 (11_Supplement): B157.

Published: 01 November 2007

View article titled, Osteoblast-induced EGFR/ERBB2 signaling in androgen-sensitive prostate carcinoma cells characterized by multiplex kinase activity profiling

Journal Articles

The discovery and mechanism of action of novel tumor-selective and apoptosis-inducing 3,5-diaryl-1,2,4-oxadiazole series using a chemical genetics approach

Katayoun A. Jessen, Nicole M. English, Jean Yu Wang, Sergei Maliartchouk, Shannon P. Archer, Ling Qiu, Regina Brand, Jared Kuemmerle, Han-Zhong Zhang, Kurt Gehlsen, John Drewe, Ben Tseng, Sui Xiong Cai, Shailaja Kasibhatla

Mol Cancer Ther (2005) 4 (5): 761–771.

https://doi.org/10.1158/1535-7163.MCT-04-0333

Published: 16 May 2005

View article titled, The discovery and mechanism of action of novel tumor-selective and apoptosis-inducing 3,5-diaryl-1,2,4-oxadiazole series using a chemical genetics approach

Includes: Supplementary data

Journal Articles

Peroxisome proliferator-activated receptor γ and retinoid X receptor ligands are potent inducers of differentiation and apoptosis in leukemias

Marina Konopleva, Elena Elstner, Teresa J. McQueen, Twee Tsao, Andrey Sudarikov, Wei Hu, Wendy D. Schober, Rui-Yu Wang, David Chism, Steven M. Kornblau, Anas Younes, Steven J. Collins, H. Phillip Koeffler, Michael Andreeff

Mol Cancer Ther (2004) 3 (10): 1249–1262.

https://doi.org/10.1158/1535-7163.1249.3.10

Published: 14 October 2004

View article titled, Peroxisome proliferator-activated receptor γ and retinoid X receptor ligands are potent inducers of differentiation and apoptosis in leukemias

Journal Articles

Genistein potentiates inhibition of tumor growth by radiation in a prostate cancer orthotopic model

Gilda G. Hillman, Yu Wang, Omer Kucuk, Mingxin Che, Daniel R. Doerge, Mark Yudelev, Michael C. Joiner, Brian Marples, Jeffrey D. Forman, Fazlul H. Sarkar

Mol Cancer Ther (2004) 3 (10): 1271–1279.

https://doi.org/10.1158/1535-7163.1271.3.10

Published: 14 October 2004

View article titled, Genistein potentiates inhibition of tumor growth by radiation in a prostate cancer orthotopic model

NARROW

Abstract A102: A comparative pharmacokinetic-pharmacodynamic-treatment study of PARP inhibitors demonstrates favorable properties for niraparib activity in preclinical tumor models

Abstract B013: Elevation of immune cell infiltration and interferon-stimulated gene expression is associated with niraparib treatment in murine syngeneic tumor models

Preclinical Activity of the Novel Anti-Prolactin Receptor (PRLR) Antibody–Drug Conjugate REGN2878-DM1 in PRLR-Positive Breast Cancers

Suppression of the Growth and Invasion of Human Head and Neck Squamous Cell Carcinomas via Regulating STAT3 Signaling and the miR-21/β-catenin Axis with HJC0152

Inhibition of HSP90 by AUY922 Preferentially Kills Mutant KRAS Colon Cancer Cells by Activating Bim through ER Stress

Activation of AR Sensitizes Breast Carcinomas to NVP-BEZ235's Therapeutic Effect Mediated by PTEN and KLLN Upregulation

PS-341 and Histone Deacetylase Inhibitor Synergistically Induce Apoptosis in Head and Neck Squamous Cell Carcinoma Cells

Interruption of RNA processing machinery by a small compound, 1-[(4-chlorophenyl)methyl]-1H-indole-3-carboxaldehyde (oncrasin-1)

Insulin-like growth factor-I receptor blockade by a specific tyrosine kinase inhibitor for human gastrointestinal carcinomas

Osteoblast-induced EGFR/ERBB2 signaling in androgen-sensitive prostate carcinoma cells characterized by multiplex kinase activity profiling

The discovery and mechanism of action of novel tumor-selective and apoptosis-inducing 3,5-diaryl-1,2,4-oxadiazole series using a chemical genetics approach

Peroxisome proliferator-activated receptor γ and retinoid X receptor ligands are potent inducers of differentiation and apoptosis in leukemias

Genistein potentiates inhibition of tumor growth by radiation in a prostate cancer orthotopic model

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