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Yoshikazu Sugimoto
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Journal Articles

APC Mutations as a Potential Biomarker for Sensitivity to Tankyrase Inhibitors in Colorectal Cancer

Noritaka Tanaka, Tetsuo Mashima, Anna Mizutani, Ayana Sato, Aki Aoyama, Bo Gong, Haruka Yoshida, Yukiko Muramatsu, Kento Nakata, Masaaki Matsuura, Ryohei Katayama, Satoshi Nagayama, Naoya Fujita, Yoshikazu Sugimoto, Hiroyuki Seimiya
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2017) 16 (4): 752–762.
https://doi.org/10.1158/1535-7163.MCT-16-0578
Published: 02 April 2017
View article titled, <em>APC</em> Mutations as a Potential Biomarker for Sensitivity to Tankyrase Inhibitors in Colorectal Cancer
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Includes: Supplementary data
Journal Articles

Abstract B62: AKT3 expression modulates chemosensitivity to aurora kinase inhibitors

Kohji Noguchi, Kazuhiro Katayama, Yoshikazu Sugimoto
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (12_Supplement_2): B62.
https://doi.org/10.1158/1535-7163.TARG-15-B62
Published: 01 December 2015
View article titled, Abstract B62: AKT3 expression modulates chemosensitivity to aurora kinase inhibitors
Journal Articles

Novel Acrylonitrile Derivatives, YHO-13177 and YHO-13351, Reverse BCRP/ABCG2-Mediated Drug Resistance In Vitro and In Vivo

Ryuta Yamazaki, Yukiko Nishiyama, Tomio Furuta, Hiroshi Hatano, Yoshiaki Igarashi, Naoyuki Asakawa, Hiroshi Kodaira, Hiroyuki Takahashi, Ritsuo Aiyama, Takeshi Matsuzaki, Nao Yagi, Yoshikazu Sugimoto
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (7): 1252–1263.
https://doi.org/10.1158/1535-7163.MCT-10-0874
Published: 06 July 2011
View article titled, Novel Acrylonitrile Derivatives, YHO-13177 and YHO-13351, Reverse BCRP/ABCG2-Mediated Drug Resistance <em>In Vitro</em> and <em>In Vivo</em>
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Journal Articles

Abstract B71: Chemosensitization to bleomycin conferred by a constitutive activation of IKK pathway in viral FLIP expressing cells

Kohji Noguchi, Yuri Masuda, Kazuhiro Katayama, Junko Mitsuhashi, Yoshikazu Sugimoto
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (12_Supplement): B71.
https://doi.org/10.1158/1535-7163.TARG-09-B71
Published: 10 December 2009
View article titled, Abstract B71: Chemosensitization to bleomycin conferred by a constitutive activation of IKK pathway in viral FLIP expressing cells
Journal Articles

YHO-13351, a novel acrylonitrile derivative, reverses BCRP/ABCG2-mediated drug resistance in vitro and in vivo

Ryuta Yamazaki, Tomio Furuta, Yukiko Nishiyama, Hiroshi Hatano, Takeshi Matsuzaki, Yoshiaki Igarashi, Hiroshi Kodaira, Ritsuo Aiyama, Shusuke Hashimoto, Yoshikazu Sugimoto
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (11_Supplement): A182.
Published: 01 November 2007
View article titled, YHO-13351, a novel acrylonitrile derivative, reverses BCRP/ABCG2-mediated drug resistance <em>in vitro</em> and <em>in vivo</em>
Journal Articles

Inhibition of the mitogen-activated protein kinase pathway results in the down-regulation of P-glycoprotein

Kazuhiro Katayama, Sho Yoshioka, Satomi Tsukahara, Junko Mitsuhashi, Yoshikazu Sugimoto
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (7): 2092–2102.
https://doi.org/10.1158/1535-7163.MCT-07-0148
Published: 09 July 2007
View article titled, Inhibition of the mitogen-activated protein kinase pathway results in the down-regulation of P-glycoprotein
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Journal Articles

A T3587G germ-line mutation of the MDR1 gene encodes a nonfunctional P-glycoprotein

Kazuyoshi Mutoh, Junko Mitsuhashi, Yasuhisa Kimura, Satomi Tsukahara, Etsuko Ishikawa, Kimie Sai, Shogo Ozawa, Jun-ichi Sawada, Kazumitsu Ueda, Kazuhiro Katayama, Yoshikazu Sugimoto
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2006) 5 (4): 877–884.
https://doi.org/10.1158/1535-7163.MCT-05-0240
Published: 28 April 2006
View article titled, A T3587G germ-line mutation of the <em>MDR1</em> gene encodes a nonfunctional P-glycoprotein
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Journal Articles

Gefitinib reverses breast cancer resistance protein–mediated drug resistance

Kae Yanase, Satomi Tsukahara, Sakiyo Asada, Etsuko Ishikawa, Yasuo Imai, Yoshikazu Sugimoto
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2004) 3 (9): 1119–1125.
https://doi.org/10.1158/1535-7163.1119.3.9
Published: 14 September 2004
View article titled, Gefitinib reverses breast cancer resistance protein–mediated drug resistance
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Journal Articles

Reversal of Breast Cancer Resistance Protein-mediated Drug Resistance by Estrogen Antagonists and Agonists

Yoshikazu Sugimoto, Satomi Tsukahara, Yasuo Imai, Yoshikazu Sugimoto, Kazumitsu Ueda, Takashi Tsuruo
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2003) 2 (1): 105–112.
Published: 01 January 2003
View article titled, Reversal of Breast Cancer Resistance Protein-mediated Drug Resistance by Estrogen Antagonists and Agonists
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Journal Articles

C421A Polymorphism in the Human Breast Cancer Resistance Protein Gene Is Associated with Low Expression of Q141K Protein and Low-Level Drug Resistance

Yasuo Imai, Minoru Nakane, Kumie Kage, Satomi Tsukahara, Etsuko Ishikawa, Takashi Tsuruo, Yoshio Miki, Yoshikazu Sugimoto
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2002) 1 (8): 611–616.
Published: 01 June 2002
View article titled, C421A Polymorphism in the Human Breast Cancer Resistance Protein Gene Is Associated with Low Expression of Q141K Protein and Low-Level Drug Resistance
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