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Journal Articles

Stereospecific PARP Trapping by BMN 673 and Comparison with Olaparib and Rucaparib

Junko Murai, Shar-Yin N. Huang, Amèlie Renaud, Yiping Zhang, Jiuping Ji, Shunichi Takeda, Joel Morris, Beverly Teicher, James H. Doroshow, Yves Pommier
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2014) 13 (2): 433–443.
DOI: https://doi.org/10.1158/1535-7163.MCT-13-0803
Published: 09 February 2014
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Includes: Supplementary data
Journal Articles

Abstract A257: Stereospecific trapping of PARP-DNA complexes by BMN 673 and comparison with olaparib and rucaparib.

Junko Murai, Shar-yin N. Huang, Amelie Renaud, Yiping Zhang, Jiuping Ji, Shunichi Takeda, Joel Morris, Beverly Teicher, James H. Doroshow, Yves Pommier
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11_Supplement): A257.
DOI: https://doi.org/10.1158/1535-7163.TARG-13-A257
Published: 01 November 2013
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Journal Articles

Abstract A214: Creating clinical target validation groups via quality assured transfer of robust clinical pharmacodynamic (PD) assays from the NCI: Improved performance of the Top1 immunoassay for analysis of tumor biopsies.

Ralph E. Parchment, Katherine Ferry-Galow, Jay Ji, Yiping Zhang, Thomas D. Pfister, Robert J. Kinders, Yvonne A. Evrard, Shivaani Kummar, Joseph E. Tomaszewski, James H. Doroshow
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11_Supplement): A214.
DOI: https://doi.org/10.1158/1535-7163.TARG-13-A214
Published: 01 November 2013
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Journal Articles

Abstract A46: A novel immunoassay (ELISA) for quantitative gamma-H2AX detection and pharmacodynamic monitoring of DNA damage induced by chemotherapeutic agents and PARP inhibitors.

Jay Ji, Yiping Zhang, Robert Kinders, Christophe Redon, Stephanie Solier, Keli Agama, Yves Pommier, William Bonner, Melinda Hollingshead, Larry Rubinstein, Alice Chen, Shivaani Kummar, Ralph E. Parchment, Joseph E. Tomaszewski, James H. Doroshow
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (11_Supplement): A46.
DOI: https://doi.org/10.1158/1535-7163.TARG-11-A46
Published: 12 November 2011
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Journal Articles

Abstract A99: Phase I trial of veliparib or mitomycin C + veliparib in pts with Fanconi anemia pathway (FA) repair defects.

Miguel A. Villalona-Calero, Wenrui Duan, Weiqiang Zhao, Li Gao, Jennifer Thurmond, Marino Leon, Konstantin Shilo, Tricia De Fiore, Judith A. Westman, Jay Ji, Yiping Zhang, John Marshall, Jeff Rose, Tanios Bekaii-Saab, Alice Chen, Gregory Otterson
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (11_Supplement): A99.
DOI: https://doi.org/10.1158/1535-7163.TARG-11-A99
Published: 12 November 2011
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Journal Articles

Phosphorylated histone H2Ax in PBMCs as a pharmacodynamic surrogate response to DNA damage by topoisomerase I inhibitors

Jay Ji, Will Yutzy, Ravithat Putvatana, Yiping Zhang, Robert Kinders, Ralph Parchment, Melinda Hollingshead, Joseph Tomaszewski, James Doroshow, Phase 0 Team and the NCI
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (11_Supplement): C49.
Published: 01 November 2007
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