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Journal Articles

Blockade of the Short Form of Prolactin Receptor Induces FOXO3a/EIF-4EBP1–Mediated Cell Death in Uterine Cancer

Yunfei Wen, Ying Wang, Anca Chelariu-Raicu, Elaine Stur, Yuan Liu, Sara Corvigno, Faith Bartsch, Lauren Redfern, Behrouz Zand, Yu Kang, Jinsong Liu, Keith Baggerly, Anil K. Sood
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2020) 19 (9): 1943–1954.
https://doi.org/10.1158/1535-7163.MCT-19-1026
Published: 02 September 2020
View articletitled, Blockade of the Short Form of Prolactin Receptor Induces FOXO3a/EIF-4EBP1–Mediated Cell Death in Uterine Cancer
Open the PDF for Blockade of the Short Form of Prolactin Receptor Induces FOXO3a/EIF-4EBP1–Mediated Cell Death in Uterine Cancer in another window
Includes: Supplementary data
Journal Articles

Predicting Novel Therapies and Targets: Regulation of Notch3 by the Bromodomain Protein BRD4

Alejandro Villar-Prados, Sherry Y. Wu, Karem A. Court, Shaolin Ma, Christopher LaFargue, Mamur A. Chowdhury, Margaret I. Engelhardt, Cristina Ivan, Prahlad T. Ram, Ying Wang, Keith Baggerly, Cristian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Shyh-Ming Yang, David J. Maloney, Makoto Yoshioka, Jeffrey W. Strovel, Jason Roszik, Anil K. Sood
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (2): 421–436.
https://doi.org/10.1158/1535-7163.MCT-18-0365
Published: 04 February 2019
View articletitled, Predicting Novel Therapies and Targets: Regulation of Notch3 by the Bromodomain Protein BRD4
Open the PDF for Predicting Novel Therapies and Targets: Regulation of Notch3 by the Bromodomain Protein BRD4 in another window
Includes: Supplementary data
Journal Articles

Abstract LB-A22: Assessment of mutations with a custom NSABP anti-HER2 resistance AmpliSeq (NAR) panel in NSABP clinical trial FB-7

Huichen Feng, Ying Wang, Peter Lucas, Seong-Rim Kim, Corey Lipchik, Patrick Gavin, Samuel Jacobs, Ashok Srinivasan, Katherine L. Pogue-Geile
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (1_Supplement): LB-A22.
https://doi.org/10.1158/1535-7163.TARG-17-LB-A22
Published: 01 January 2018
View articletitled, Abstract LB-A22: Assessment of mutations with a custom NSABP anti-HER2 resistance AmpliSeq (NAR) panel in NSABP clinical trial FB-7
Journal Articles

Abstract LB-B22: TNBC kinase prioritization for targeted therapy after chemotherapy resistance

Bora Lim, In Ah Park, Ying Wang, Lakshmi Bollu, Powel Brown, Keith Baggerly, Funda Meric-Bernstam, Naoto Ueno
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (1_Supplement): LB-B22.
https://doi.org/10.1158/1535-7163.TARG-17-LB-B22
Published: 01 January 2018
View articletitled, Abstract LB-B22: TNBC kinase prioritization for targeted therapy after chemotherapy resistance
Journal Articles

Abstract B089: MicroRNA (miR) 214-3p targets ras-related protein14 (RAB14) to inhibit cell migration and invasion in esophageal cancer cells

Pornima Phatak, Jaladanki N. Rao, Carol B. Fowler, Douglas J. Turner, Jian-Ying Wang, James M. Donahue
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (1_Supplement): B089.
https://doi.org/10.1158/1535-7163.TARG-17-B089
Published: 01 January 2018
View articletitled, Abstract B089: MicroRNA (miR) 214-3p targets ras-related protein14 (RAB14) to inhibit cell migration and invasion in esophageal cancer cells
Journal Articles

Dual Inhibition of NOX2 and Receptor Tyrosine Kinase by BJ-1301 Enhances Anticancer Therapy Efficacy via Suppression of Autocrine-Stimulatory Factors in Lung Cancer

Jaya Gautam, Jin-Mo Ku, Sushil Chandra Regmi, Hyunyoung Jeong, Ying Wang, Suhrid Banskota, Myo-Hyeon Park, Tae-gyu Nam, Byeong-Seon Jeong, Jung-Ae Kim
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2017) 16 (10): 2144–2156.
https://doi.org/10.1158/1535-7163.MCT-16-0915
Published: 02 October 2017
View articletitled, Dual Inhibition of NOX2 and Receptor Tyrosine Kinase by BJ-1301 Enhances Anticancer Therapy Efficacy via Suppression of Autocrine-Stimulatory Factors in Lung Cancer
Open the PDF for Dual Inhibition of NOX2 and Receptor Tyrosine Kinase by BJ-1301 Enhances Anticancer Therapy Efficacy via Suppression of Autocrine-Stimulatory Factors in Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Severely Impaired and Dysregulated Cytochrome P450 Expression and Activities in Hepatocellular Carcinoma: Implications for Personalized Treatment in Patients

Tongmeng Yan, Linlin Lu, Cong Xie, Jiamei Chen, Xiaojuan Peng, Lijun Zhu, Ying Wang, Qiang Li, Jian Shi, Fuyuan Zhou, Ming Hu, Zhongqiu Liu
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (12): 2874–2886.
https://doi.org/10.1158/1535-7163.MCT-15-0274
Published: 06 December 2015
View articletitled, Severely Impaired and Dysregulated Cytochrome P450 Expression and Activities in Hepatocellular Carcinoma: Implications for Personalized Treatment in Patients
Open the PDF for Severely Impaired and Dysregulated Cytochrome P450 Expression and Activities in Hepatocellular Carcinoma: Implications for Personalized Treatment in Patients in another window
Includes: Supplementary data
Journal Articles

Abstract A24: Beta-klotho expression is associated with the antitumor activity of pan-FGFR inhibitor in human malignancies with FGF19 amplification

Amelie Forest, Sandra Nakasone, Ying Wang, Xuemei Guo, Timothy R. Mack, Genshi Zhao, Yong G. Yue, Xueqian Gong, Trent Stewart, Sean Buchanan, Christoph Reinhard, Ruslan Novosiadly
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (12_Supplement_2): A24.
https://doi.org/10.1158/1535-7163.TARG-15-A24
Published: 01 December 2015
View articletitled, Abstract A24: Beta-klotho expression is associated with the antitumor activity of pan-FGFR inhibitor in human malignancies with FGF19 amplification
Journal Articles

Concordance of Genomic Alterations between Primary and Recurrent Breast Cancer

Funda Meric-Bernstam, Garrett M. Frampton, Jaime Ferrer-Lozano, Roman Yelensky, Jose A. Pérez-Fidalgo, Ying Wang, Gary A. Palmer, Jeffrey S. Ross, Vincent A. Miller, Xiaoping Su, Pilar Eroles, Juan Antonio Barrera, Octavio Burgues, Ana M. Lluch, Xiaofeng Zheng, Aysegul Sahin, Philip J. Stephens, Gordon B. Mills, Maureen T. Cronin, Ana M. Gonzalez-Angulo
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2014) 13 (5): 1382–1389.
https://doi.org/10.1158/1535-7163.MCT-13-0482
Published: 05 May 2014
View articletitled, Concordance of Genomic Alterations between Primary and Recurrent Breast Cancer
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Includes: Supplementary data
Journal Articles

Abstract B227: Overexpression of microRNA 214-3p in esophageal cancer cells enhances sensitivity to chemotherapy-induced apoptosis by targeting CUG-binding protein 1 (CUGBP1) and survivin.

Pornima Phatak, Daniel Mansour, Kimberly Byrnes, Shan Cao, Lan Liu, Ruiyun Li, Rao Jaladanki, Douglas J. Tuner, Jian Ying Wang, James M. Donahue
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11_Supplement): B227.
https://doi.org/10.1158/1535-7163.TARG-13-B227
Published: 01 November 2013
View articletitled, Abstract B227: Overexpression of microRNA 214-3p in esophageal cancer cells enhances sensitivity to chemotherapy-induced apoptosis by targeting CUG-binding protein 1 (CUGBP1) and survivin.
Journal Articles

Abstract B285: A novel, potent, highly selective inhibitor of c-Met kinase, Simm559, inhibits c-Met-dependent neoplastic phenotypes in vitro and in vivo.

Jing Ai, ZhengSheng Zhan, Ying Wang, Fang Chen, Xia Peng, Yi Chen, Yinchun Ji, Jian Ding, Meiyu Geng, Wenhu Duan
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11_Supplement): B285.
https://doi.org/10.1158/1535-7163.TARG-13-B285
Published: 01 November 2013
View articletitled, Abstract B285: A novel, potent, highly selective inhibitor of c-Met kinase, Simm559, inhibits c-Met-dependent neoplastic phenotypes in vitro and in vivo.
Journal Articles

Abstract A235: Anti-CSF-1R antibodies reduce tumor-associated macrophages and inhibit tumor growth in preclinical models.

Yanxia Li, Sneha Mathew, Lan Wu, Ying Wang, Kris Persaud, Douglas Burtrum, Paul Balderes, David Surguladze, John Haurum, Dale Ludwig, Jacqueline Doody
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11_Supplement): A235.
https://doi.org/10.1158/1535-7163.TARG-13-A235
Published: 01 November 2013
View articletitled, Abstract A235: Anti-CSF-1R antibodies reduce tumor-associated macrophages and inhibit tumor growth in preclinical models.
Journal Articles

Cell Intrinsic Role of COX-2 in Pancreatic Cancer Development

Reginald Hill, Yunfeng Li, Linh M. Tran, Sarah Dry, Joseph Hargan Calvopina, Alejandro Garcia, Christine Kim, Ying Wang, Timothy R. Donahue, Harvey R. Herschman, Hong Wu
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2012) 11 (10): 2127–2137.
https://doi.org/10.1158/1535-7163.MCT-12-0342
Published: 09 October 2012
View articletitled, Cell Intrinsic Role of COX-2 in Pancreatic Cancer Development
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Includes: Supplementary data
Journal Articles

Abstract C224: Anti-CSF-1R antibodies reduce tumor-associated macrophages and inhibit tumor growth in preclinical models.

Yanxia Li, Sneha Mathew, Lan Wu, Ying Wang, Jessica Kearney, Kris Persaud, Douglas Burtrum, Paul Balderes, David Surguladze, James Tonra, John Haurum, Dale Ludwig, Jacqueline F. Doody
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (11_Supplement): C224.
https://doi.org/10.1158/1535-7163.TARG-11-C224
Published: 12 November 2011
View articletitled, Abstract C224: Anti-CSF-1R antibodies reduce tumor-associated macrophages and inhibit tumor growth in preclinical models.
Journal Articles

Thymoquinone inhibits tumor angiogenesis and tumor growth through suppressing AKT and extracellular signal-regulated kinase signaling pathways

Tingfang Yi, Sung-Gook Cho, Zhengfang Yi, Xiufeng Pang, Melissa Rodriguez, Ying Wang, Gautam Sethi, Bharat B. Aggarwal, Mingyao Liu
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (7): 1789–1796.
https://doi.org/10.1158/1535-7163.MCT-08-0124
Published: 21 July 2008
View articletitled, Thymoquinone inhibits tumor angiogenesis and tumor growth through suppressing AKT and extracellular signal-regulated kinase signaling pathways
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Journal Articles

17-Acetoxyjolkinolide B irreversibly inhibits IκB kinase and induces apoptosis of tumor cells

Shou-Sheng Yan, Ying Li, Ying Wang, Shen-Si Shen, Yuan Gu, Hong-Bing Wang, Guo-Wei Qin, Qiang Yu
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (6): 1523–1532.
https://doi.org/10.1158/1535-7163.MCT-08-0263
Published: 19 June 2008
View articletitled, 17-Acetoxyjolkinolide B irreversibly inhibits IκB kinase and induces apoptosis of tumor cells
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Journal Articles

Inhibitory activity of cetuximab on epidermal growth factor receptor mutations in non–small cell lung cancers

Jacqueline F. Doody, Ying Wang, Sheetal N. Patel, Christopher Joynes, Sui Ping Lee, Jason Gerlak, Robin L. Rolser, Yanxia Li, Philipp Steiner, Rajiv Bassi, Dan J. Hicklin, Yaron R. Hadari
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (10): 2642–2651.
https://doi.org/10.1158/1535-7163.MCT-06-0506
Published: 15 October 2007
View articletitled, Inhibitory activity of cetuximab on epidermal growth factor receptor mutations in non–small cell lung cancers
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Journal Articles

Sorafenib inhibits the angiogenesis and growth of orthotopic anaplastic thyroid carcinoma xenografts in nude mice

Seungwon Kim, Yasemin D. Yazici, Gabriel Calzada, Zhuo-Ying Wang, Maher N. Younes, Samar A. Jasser, Adel K. El-Naggar, Jeffrey N. Myers
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (6): 1785–1792.
https://doi.org/10.1158/1535-7163.MCT-06-0595
Published: 15 June 2007
View articletitled, Sorafenib inhibits the angiogenesis and growth of orthotopic anaplastic thyroid carcinoma xenografts in nude mice
Open the PDF for Sorafenib inhibits the angiogenesis and growth of orthotopic anaplastic thyroid carcinoma xenografts in nude mice in another window