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Journal Articles

In Vivo and In Vitro Efficacy of Trastuzumab Deruxtecan in Uterine Serous Carcinoma

Mol Cancer Ther (2023) 22 (12): 1404–1412.

https://doi.org/10.1158/1535-7163.MCT-23-0126

Published: 01 December 2023

View article titled, In Vivo and In Vitro Efficacy of Trastuzumab Deruxtecan in Uterine Serous Carcinoma

Journal Articles

Runx2 Deficiency in Osteoblasts Promotes Myeloma Resistance to Bortezomib by Increasing TSP-1–Dependent TGFβ1 Activation and Suppressing Immunity in Bone Marrow

Chao Zhang, Xiaoxuan Xu, Timothy N. Trotter, Pramod S. Gowda, Yun Lu, Mark J. Suto, Amjad Javed, Joanne E. Murphy-Ullrich, Juan Li, Yang Yang

Mol Cancer Ther (2022) 21 (2): 347–358.

https://doi.org/10.1158/1535-7163.MCT-21-0310

Published: 08 February 2022

View article titled, Runx2 Deficiency in Osteoblasts Promotes Myeloma Resistance to Bortezomib by Increasing TSP-1–Dependent TGFβ1 Activation and Suppressing Immunity in Bone Marrow

Includes: Supplementary data

Journal Articles

A Benzenesulfonamide-Based Mitochondrial Uncoupler Induces Endoplasmic Reticulum Stress and Immunogenic Cell Death in Epithelial Ovarian Cancer

Fangfang Bi, Ziyan Jiang, Wonmin Park, Tobias M.P. Hartwich, Zhiping Ge, Kay Y. Chong, Kevin Yang, Madeline J. Morrison, Dongin Kim, Jaeyeon Kim, Wen Zhang, Liliia M. Kril, David S. Watt, Chunming Liu, Yang Yang-Hartwich

Mol Cancer Ther (2021) 20 (12): 2398–2409.

https://doi.org/10.1158/1535-7163.MCT-21-0396

Published: 03 December 2021

View article titled, A Benzenesulfonamide-Based Mitochondrial Uncoupler Induces Endoplasmic Reticulum Stress and Immunogenic Cell Death in Epithelial Ovarian Cancer

Includes: Supplementary data

Journal Articles

Sorafenib and Carfilzomib Synergistically Inhibit the Proliferation, Survival, and Metastasis of Hepatocellular Carcinoma

Chao Jiang, Rui Xu, Xiao-Xing Li, Yu-Feng Zhou, Xiao-Yi Xu, Yang Yang, Hui-Yun Wang, X.F. Steven Zheng

Mol Cancer Ther (2018) 17 (12): 2610–2621.

https://doi.org/10.1158/1535-7163.MCT-17-0541

Published: 03 December 2018

View article titled, Sorafenib and Carfilzomib Synergistically Inhibit the Proliferation, Survival, and Metastasis of Hepatocellular Carcinoma

Journal Articles

Repositioning Dopamine D2 Receptor Agonist Bromocriptine to Enhance Docetaxel Chemotherapy and Treat Bone Metastatic Prostate Cancer

Yang Yang, Kenza Mamouni, Xin Li, Yanhua Chen, Sravan Kavuri, Yuhong Du, Haian Fu, Omer Kucuk, Daqing Wu

Mol Cancer Ther (2018) 17 (9): 1859–1870.

https://doi.org/10.1158/1535-7163.MCT-17-1176

Published: 04 September 2018

View article titled, Repositioning Dopamine D2 Receptor Agonist Bromocriptine to Enhance Docetaxel Chemotherapy and Treat Bone Metastatic Prostate Cancer

Includes: Supplementary data

Journal Articles

Chikusetsusaponin IVa Butyl Ester (CS-IVa-Be), a Novel IL6R Antagonist, Inhibits IL6/STAT3 Signaling Pathway and Induces Cancer Cell Apoptosis

Jie Yang, Shihui Qian, Xueting Cai, Wuguang Lu, Chunping Hu, Xiaoyan Sun, Yang Yang, Qiang Yu, S. Paul Gao, Peng Cao

Mol Cancer Ther (2016) 15 (6): 1190–1200.

https://doi.org/10.1158/1535-7163.MCT-15-0551

Published: 02 June 2016

View article titled, Chikusetsusaponin IVa Butyl Ester (CS-IVa-Be), a Novel IL6R Antagonist, Inhibits IL6/STAT3 Signaling Pathway and Induces Cancer Cell Apoptosis

Includes: Supplementary data

Journal Articles

TRX-E-002-1 Induces c-Jun–Dependent Apoptosis in Ovarian Cancer Stem Cells and Prevents Recurrence In Vivo

Ayesha B. Alvero, Andrew Heaton, Eydis Lima, Mary Pitruzzello, Natalia Sumi, Yang Yang-Hartwich, Carlos Cardenas, Sahra Steinmacher, Dan-Arin Silasi, David Brown, Gil Mor

Mol Cancer Ther (2016) 15 (6): 1279–1290.

https://doi.org/10.1158/1535-7163.MCT-16-0005

Published: 02 June 2016

View article titled, TRX-E-002-1 Induces c-Jun–Dependent Apoptosis in Ovarian Cancer Stem Cells and Prevents Recurrence In Vivo

Includes: Multimedia, Supplementary data

Journal Articles

Inhibition of SIRT1 Signaling Sensitizes the Antitumor Activity of Silybin against Human Lung Adenocarcinoma Cells In Vitro and In Vivo

Zhenxing Liang, Yang Yang, Haibin Wang, Wei Yi, Xiaolong Yan, Juanjuan Yan, Yue Li, Yingtong Feng, Shiqiang Yu, Jian Yang, Zhenxiao Jin, Weixun Duan, Wensheng Chen

Mol Cancer Ther (2014) 13 (7): 1860–1872.

https://doi.org/10.1158/1535-7163.MCT-13-0942

Published: 06 July 2014

View article titled, Inhibition of SIRT1 Signaling Sensitizes the Antitumor Activity of Silybin against Human Lung Adenocarcinoma Cells In Vitro and In Vivo

Journal Articles

Abstract A139: Discovery and biological profiling of potent fibroblast growth factor receptor (FGFR) kinase inhibitors derived from in silico design with in vivo antitumor activity against FGFR2‐dependent human tumors

Mol Cancer Ther (2009) 8 (12_Supplement): A139.

https://doi.org/10.1158/1535-7163.TARG-09-A139

Published: 10 December 2009

View article titled, Abstract A139: Discovery and biological profiling of potent fibroblast growth factor receptor (FGFR) kinase inhibitors derived from in silico design with in vivo antitumor activity against FGFR2‐dependent human tumors

Journal Articles

The antitumor effects of sunitinib (formerly SU11248) against a variety of human hematologic malignancies: enhancement of growth inhibition via inhibition of mammalian target of rapamycin signaling

Takayuki Ikezoe, Chie Nishioka, Taizo Tasaka, Yang Yang, Naoki Komatsu, Kazuto Togitani, H. Phillip Koeffler, Hirokuni Taguchi

Mol Cancer Ther (2006) 5 (10): 2522–2530.

https://doi.org/10.1158/1535-7163.MCT-06-0071

Published: 13 October 2006

View article titled, The antitumor effects of sunitinib (formerly SU11248) against a variety of human hematologic malignancies: enhancement of growth inhibition via inhibition of mammalian target of rapamycin signaling

Journal Articles

Oridonin, a diterpenoid purified from Rabdosia rubescens, inhibits the proliferation of cells from lymphoid malignancies in association with blockade of the NF-κB signal pathways

Takayuki Ikezoe, Yang Yang, Kentaro Bandobashi, Tsuyako Saito, Shigeki Takemoto, Hisanori Machida, Kazuto Togitani, H. Phillip Koeffler, Hirokuni Taguchi

Mol Cancer Ther (2005) 4 (4): 578–586.

https://doi.org/10.1158/1535-7163.MCT-04-0277

Published: 12 April 2005

View article titled, Oridonin, a diterpenoid purified from Rabdosia rubescens, inhibits the proliferation of cells from lymphoid malignancies in association with blockade of the NF-κB signal pathways

Journal Articles

HIV-1 protease inhibitor induces growth arrest and apoptosis of human multiple myeloma cells via inactivation of signal transducer and activator of transcription 3 and extracellular signal-regulated kinase 1/2

Takayuki Ikezoe, Tsuyako Saito, Kentaro Bandobashi, Yang Yang, H. Phillip Koeffler, Hirokuni Taguchi

Mol Cancer Ther (2004) 3 (4): 473–479.

https://doi.org/10.1158/1535-7163.473.3.4

Published: 12 April 2004

View article titled, HIV-1 protease inhibitor induces growth arrest and apoptosis of human multiple myeloma cells via inactivation of signal transducer and activator of transcription 3 and extracellular signal-regulated kinase 1/2

NARROW

In Vivo and In Vitro Efficacy of Trastuzumab Deruxtecan in Uterine Serous Carcinoma

Runx2 Deficiency in Osteoblasts Promotes Myeloma Resistance to Bortezomib by Increasing TSP-1–Dependent TGFβ1 Activation and Suppressing Immunity in Bone Marrow

A Benzenesulfonamide-Based Mitochondrial Uncoupler Induces Endoplasmic Reticulum Stress and Immunogenic Cell Death in Epithelial Ovarian Cancer

Sorafenib and Carfilzomib Synergistically Inhibit the Proliferation, Survival, and Metastasis of Hepatocellular Carcinoma

Repositioning Dopamine D2 Receptor Agonist Bromocriptine to Enhance Docetaxel Chemotherapy and Treat Bone Metastatic Prostate Cancer

Chikusetsusaponin IVa Butyl Ester (CS-IVa-Be), a Novel IL6R Antagonist, Inhibits IL6/STAT3 Signaling Pathway and Induces Cancer Cell Apoptosis

TRX-E-002-1 Induces c-Jun–Dependent Apoptosis in Ovarian Cancer Stem Cells and Prevents Recurrence In Vivo

Inhibition of SIRT1 Signaling Sensitizes the Antitumor Activity of Silybin against Human Lung Adenocarcinoma Cells In Vitro and In Vivo

Abstract A139: Discovery and biological profiling of potent fibroblast growth factor receptor (FGFR) kinase inhibitors derived from in silico design with in vivo antitumor activity against FGFR2‐dependent human tumors

The antitumor effects of sunitinib (formerly SU11248) against a variety of human hematologic malignancies: enhancement of growth inhibition via inhibition of mammalian target of rapamycin signaling

Oridonin, a diterpenoid purified from Rabdosia rubescens, inhibits the proliferation of cells from lymphoid malignancies in association with blockade of the NF-κB signal pathways

HIV-1 protease inhibitor induces growth arrest and apoptosis of human multiple myeloma cells via inactivation of signal transducer and activator of transcription 3 and extracellular signal-regulated kinase 1/2

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