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Journal Articles

Preclinical Evaluation of 9MW2821, a Site-Specific Monomethyl Auristatin E–based Antibody–Drug Conjugate for Treatment of Nectin-4–expressing Cancers

Wei Zhou, Peng Fang, Dongan Yu, Hongyuan Ren, Meng You, Long Yin, Fei Mei, Huikai Zhu, Zhenzhen Wang, Hui Xu, Yuxia Cao, Xiaowei Sun, Xiaohong Xu, Jianjun Bi, Jin Wang, Lanping Ma, Xin Wang, Lin Chen, Yongliang Zhang, Xiaowei Cen, Xi Zhu, Liguang Lou, Datao Liu, Xiaoding Tan, Jinliang Yang, Tao Meng, Jingkang Shen
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2023) 22 (8): 913–925.
https://doi.org/10.1158/1535-7163.MCT-22-0743
Published: 01 August 2023
View article titled, Preclinical Evaluation of 9MW2821, a Site-Specific Monomethyl Auristatin E–based Antibody–Drug Conjugate for Treatment of Nectin-4–expressing Cancers
Open the PDF for Preclinical Evaluation of 9MW2821, a Site-Specific Monomethyl Auristatin E–based Antibody–Drug Conjugate for Treatment of Nectin-4–expressing Cancers in another window
Includes: Supplementary data
Journal Articles

Dual Mechanisms of Novel CD73-Targeted Antibody and Antibody–Drug Conjugate in Inhibiting Lung Tumor Growth and Promoting Antitumor Immune-Effector Function

Rui Jin, Liang Liu, Yun Xing, Tao Meng, Lanping Ma, Jinpeng Pei, Ying Cong, Xuesai Zhang, Zhiqiang Ren, Xin Wang, Jingkang Shen, Ker Yu
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2020) 19 (11): 2340–2352.
https://doi.org/10.1158/1535-7163.MCT-20-0076
Published: 03 November 2020
View article titled, Dual Mechanisms of Novel CD73-Targeted Antibody and Antibody–Drug Conjugate in Inhibiting Lung Tumor Growth and Promoting Antitumor Immune-Effector Function
Open the PDF for Dual Mechanisms of Novel CD73-Targeted Antibody and Antibody–Drug Conjugate in Inhibiting Lung Tumor Growth and Promoting Antitumor Immune-Effector Function in another window
Includes: Supplementary data
Journal Articles

Abstract C065: Dietary deprivation of non-essential amino acids improves anti-PD-1 immunotherapy in murine colon cancer

Zehui Li, Grace Yang, Shuang Zhou, Xin Wang, Xiyan Li
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (12_Supplement): C065.
https://doi.org/10.1158/1535-7163.TARG-19-C065
Published: 01 December 2019
View article titled, Abstract C065: Dietary deprivation of non-essential amino acids improves anti-PD-1 immunotherapy in murine colon cancer
Journal Articles

Abstract A134: Functional perturbation of PARP6 affects centromeric proteins and is associated with increased multi-polar spindles in breast cancer cell lines.

SHAUN GROSSKURTH, Philip Petteruti, Xin Wang, Keith Mikule
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11_Supplement): A134.
https://doi.org/10.1158/1535-7163.TARG-13-A134
Published: 01 November 2013
View article titled, Abstract A134: Functional perturbation of PARP6 affects centromeric proteins and is associated with increased multi-polar spindles in breast cancer cell lines.
Journal Articles

Abstract A221: Novel PARP6 inhibitors demonstrate in vivo efficacy in xenograft models.

Michele F. Mayo, Shaun Grosskurth, Xin Wang, Philip Petteruti, Prasad Nadella, Corinne Reimer, Keith Mikule
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11_Supplement): A221.
https://doi.org/10.1158/1535-7163.TARG-13-A221
Published: 01 November 2013
View article titled, Abstract A221: Novel PARP6 inhibitors demonstrate <em>in vivo</em> efficacy in xenograft models.
Journal Articles

Apigenin Induces Apoptosis in Human Leukemia Cells and Exhibits Anti-Leukemic Activity In Vivo

Amit Budhraja, Ning Gao, Zhuo Zhang, Young-Ok Son, Senping Cheng, Xin Wang, Songze Ding, Andrew Hitron, Gang Chen, Jia Luo, Xianglin Shi
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2012) 11 (1): 132–142.
https://doi.org/10.1158/1535-7163.MCT-11-0343
Published: 09 January 2012
View article titled, Apigenin Induces Apoptosis in Human Leukemia Cells and Exhibits Anti-Leukemic Activity <em>In Vivo</em>
Open the PDF for Apigenin Induces Apoptosis in Human Leukemia Cells and Exhibits Anti-Leukemic Activity <em>In Vivo</em> in another window
Includes: Supplementary data