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Journal Articles

Expanding the Repertoire for “Large Small Molecules”: Prodrug ABBV-167 Efficiently Converts to Venetoclax with Reduced Food Effect in Healthy Volunteers

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Ahmed Hamed Salem, Zhi-Fu Tao, Orlando F. Bueno, Jie Chen, Shuang Chen, Rohinton Edalji, Steven W. Elmore, Keith M. Fournier, Kaid C. Harper, Richard Hong, Gary J. Jenkins, Jianguo Ji, Russell A. Judge, John C. Kalvass, Russell C. Klix, Yi-Yin Ku, Joel D. Leverson, Richard A. Marks, Kennan C. Marsh, Rajeev M. Menon, Chang H. Park, Darren C. Phillips, Yu-Ming Pu, Saul H. Rosenberg, Yeshwant D. Sanzgiri, Ahmad Y. Sheikh, Yi Shi, Deanne Stolarik, Ahmed A. Suleiman, Xilu Wang, Geoff G.Z. Zhang, Nathaniel D. Catron, Andrew J. Souers
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (6): 999–1008.
https://doi.org/10.1158/1535-7163.MCT-21-0077
Published: 01 June 2021
View articletitled, Expanding the Repertoire for “Large Small Molecules”: Prodrug ABBV-167 Efficiently Converts to Venetoclax with Reduced Food Effect in Healthy Volunteers
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Includes: Supplementary data