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Journal Articles

Design and Evaluation of ZD06519, a Novel Camptothecin Payload for Antibody Drug Conjugates

Mark E. Petersen, Michael G. Brant, Manuel Lasalle, Samir Das, Renee Duan, Jodi Wong, Tong Ding, Kaylee J. Wu, Dayananda Siddappa, Chen Fang, Wen Zhang, Alex M. L. Wu, Truman Hirkala-Schaefer, Graham A. E. Garnett, Vincent Fung, Luying Yang, Andrea Hernandez Rojas, Samuel O. Lawn, Stuart D. Barnscher, Jamie R. Rich, Raffaele Colombo
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2024) 23 (5): 606–618.
https://doi.org/10.1158/1535-7163.MCT-23-0822
Published: 02 May 2024
View article titled, Design and Evaluation of ZD06519, a Novel Camptothecin Payload for Antibody Drug Conjugates
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Includes: Supplementary data
Journal Articles

Diaminobutoxy-substituted Isoflavonoid (DBI-1) Enhances the Therapeutic Efficacy of GLUT1 Inhibitor BAY-876 by Modulating Metabolic Pathways in Colon Cancer Cells

Lichao Guo, Wen Zhang, Yanqi Xie, Xi Chen, Emma E. Olmstead, Mengqiang Lian, Baochen Zhang, Yekaterina Y. Zaytseva, B. Mark Evers, H. Peter Spielmann, Xifu Liu, David S. Watt, Chunming Liu
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2022) 21 (5): 740–750.
https://doi.org/10.1158/1535-7163.MCT-21-0925
Published: 04 May 2022
View article titled, Diaminobutoxy-substituted Isoflavonoid (DBI-1) Enhances the Therapeutic Efficacy of GLUT1 Inhibitor BAY-876 by Modulating Metabolic Pathways in Colon Cancer Cells
Open the PDF for Diaminobutoxy-substituted Isoflavonoid (DBI-1) Enhances the Therapeutic Efficacy of GLUT1 Inhibitor BAY-876 by Modulating Metabolic Pathways in Colon Cancer Cells in another window
Includes: Supplementary data
Journal Articles

A Benzenesulfonamide-Based Mitochondrial Uncoupler Induces Endoplasmic Reticulum Stress and Immunogenic Cell Death in Epithelial Ovarian Cancer

Fangfang Bi, Ziyan Jiang, Wonmin Park, Tobias M.P. Hartwich, Zhiping Ge, Kay Y. Chong, Kevin Yang, Madeline J. Morrison, Dongin Kim, Jaeyeon Kim, Wen Zhang, Liliia M. Kril, David S. Watt, Chunming Liu, Yang Yang-Hartwich
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (12): 2398–2409.
https://doi.org/10.1158/1535-7163.MCT-21-0396
Published: 03 December 2021
View article titled, A Benzenesulfonamide-Based Mitochondrial Uncoupler Induces Endoplasmic Reticulum Stress and Immunogenic Cell Death in Epithelial Ovarian Cancer
Open the PDF for A Benzenesulfonamide-Based Mitochondrial Uncoupler Induces Endoplasmic Reticulum Stress and Immunogenic Cell Death in Epithelial Ovarian Cancer in another window
Includes: Supplementary data
Journal Articles

Potent Synergistic Effect on C-Myc–Driven Colorectal Cancers Using a Novel Indole-Substituted Quinoline with a Plk1 Inhibitor

Yanqi Xie, Wen Zhang, Lichao Guo, Liliia M. Kril, Kristin L. Begley, Vitaliy M. Sviripa, Xi Chen, Xifu Liu, Eun Y. Lee, Daheng He, Chi Wang, Tianyan Gao, Xiaoqi Liu, B. Mark Evers, David S. Watt, Chunming Liu
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (10): 1893–1903.
https://doi.org/10.1158/1535-7163.MCT-20-1017
Published: 01 October 2021
View article titled, Potent Synergistic Effect on C-Myc–Driven Colorectal Cancers Using a Novel Indole-Substituted Quinoline with a Plk1 Inhibitor
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Includes: Supplementary data
Journal Articles

Abstract B4: Evaluation of VEGFxxxb isoforms as a predictive biomarker for anti-VEGF cancer therapy.

Wen Zhang, Cristina Abrahams, Ying Huang, Baosheng Li, Asma Parveen, Min Ni, Yi Wei, Yueming Ding, Eric Zhang, Hsin Chieh Lin, Gavin Thurston, Qing Zhang
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11_Supplement): B4.
https://doi.org/10.1158/1535-7163.TARG-13-B4
Published: 01 November 2013
View article titled, Abstract B4: Evaluation of VEGF<sub>xxx</sub>b isoforms as a predictive biomarker for anti-VEGF cancer therapy.
Journal Articles

Strengthening Context-Dependent Anticancer Effects on Non–Small Cell Lung Carcinoma by Inhibition of Both MET and EGFR

Yu-Wen Zhang, Ben Staal, Curt Essenburg, Steven Lewis, Dafna Kaufman, George F. Vande Woude
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (8): 1429–1441.
https://doi.org/10.1158/1535-7163.MCT-13-0016
Published: 08 August 2013
View article titled, Strengthening Context-Dependent Anticancer Effects on Non–Small Cell Lung Carcinoma by Inhibition of Both MET and EGFR
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Includes: Supplementary data
Journal Articles

Therapeutic potential of hepatocyte growth factor/scatter factor neutralizing antibodies: Inhibition of tumor growth in both autocrine and paracrine hepatocyte growth factor/scatter factor:c-Met-driven models of leiomyosarcoma

Chong-Feng Gao, Qian Xie, Yu-Wen Zhang, Yanli Su, Ping Zhao, Brian Cao, Kyle Furge, Jan Sun, Karen Rex, Tao Osgood, Angela Coxon, Teresa L. Burgess, George F. Vande Woude
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (10): 2803–2810.
https://doi.org/10.1158/1535-7163.MCT-09-0125
Published: 12 October 2009
View article titled, Therapeutic potential of hepatocyte growth factor/scatter factor neutralizing antibodies: Inhibition of tumor growth in both autocrine and paracrine hepatocyte growth factor/scatter factor:c-Met-driven models of leiomyosarcoma
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Journal Articles

MFTZ-1, an actinomycetes subspecies–derived antitumor macrolide, functions as a novel topoisomerase II poison

Cheng-Ying Xie, Hong Zhu, Li-Ping Lin, Ze-Hong Miao, Mei-Yu Geng, Yu-Jun Cai, Yi Chen, Hua-Jun Zhao, Hai-Bin Luo, Xiong-Wen Zhang, Li-Ming Fan, Yue-Mao Shen, Jian Ding
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (11): 3059–3070.
https://doi.org/10.1158/1535-7163.MCT-07-0014
Published: 19 November 2007
View article titled, MFTZ-1, an actinomycetes subspecies–derived antitumor macrolide, functions as a novel topoisomerase II poison
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