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Journal Articles

ANXA1 Binds and Stabilizes EGFR to Promote Nasopharyngeal Carcinoma Radioresistance

Available to Purchase
Ting Zeng, Ding Xiao, Wei Zhu, Di Wu, Hong Yi, Wei Huang, Shan-Shan Lu, Zheng-Zheng Yu, Qi Wen, Yun-Xi Peng, Li Yuan, Zhi-Qiang Xiao, Jinwu Peng
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther OF1–OF15.
https://doi.org/10.1158/1535-7163.MCT-24-0944
Published: 20 June 2025
View articletitled, ANXA1 Binds and Stabilizes EGFR to Promote Nasopharyngeal Carcinoma Radioresistance
Open the PDF for ANXA1 Binds and Stabilizes EGFR to Promote Nasopharyngeal Carcinoma Radioresistance in another window
Includes: Supplementary data
Journal Articles

Discovery of RGT-018: A Potent, Selective, and Orally Bioavailable SOS1 Inhibitor for KRAS-Driven Cancers

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Fei Xiao, Kailiang Wang, Xinjuan Wang, Huijuan Li, Zhilong Hu, Xiaoming Ren, Wei Huang, Teng Feng, Lili Yao, Jing Lin, Chunlai Li, Zhuanzhuan Zhang, Liufeng Mei, Xiaotian Zhu, Wenge Zhong, Zhi Xie
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2024) 23 (12): 1703–1716.
https://doi.org/10.1158/1535-7163.MCT-24-0049
Published: 03 December 2024
View articletitled, Discovery of RGT-018: A Potent, Selective, and Orally Bioavailable SOS1 Inhibitor for KRAS-Driven Cancers
Open the PDF for Discovery of RGT-018: A Potent, Selective, and Orally Bioavailable SOS1 Inhibitor for KRAS-Driven Cancers in another window
Includes: Supplementary data
Journal Articles

Abstract P241: A highly potent HPK1 inhibitor augments immune cell activation and anti-tumor immunity in a syngeneic tumor mouse model

Free
Hao Liu, Lei Wu, Song Feng, Wei Huang, Huijuan Li, Jing Lin, Yangyang Liu, Liufeng Mei, Baoqi Ren, Julie Xie, Lili Yao, Wenge Zhong
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (12_Supplement): P241.
https://doi.org/10.1158/1535-7163.TARG-21-P241
Published: 01 December 2021
View articletitled, Abstract P241: A highly potent HPK1 inhibitor augments immune cell activation and anti-tumor immunity in a syngeneic tumor mouse model
Journal Articles

PLK1 and NOTCH Positively Correlate in Melanoma and Their Combined Inhibition Results in Synergistic Modulations of Key Melanoma Pathways

Free
Shengqin Su, Gagan Chhabra, Mary A. Ndiaye, Chandra K. Singh, Ting Ye, Wei Huang, Colin N. Dewey, Vijayasaradhi Setaluri, Nihal Ahmad
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (1): 161–172.
https://doi.org/10.1158/1535-7163.MCT-20-0654
Published: 05 January 2021
View articletitled, PLK1 and NOTCH Positively Correlate in Melanoma and Their Combined Inhibition Results in Synergistic Modulations of Key Melanoma Pathways
Open the PDF for PLK1 and NOTCH Positively Correlate in Melanoma and Their Combined Inhibition Results in Synergistic Modulations of Key Melanoma Pathways in another window
Includes: Supplementary data
Journal Articles

Retraction: MiR-125b Increases Nasopharyngeal Carcinoma Radioresistance By Targeting A20/NF-κB Signaling Pathway

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Li-Na Li, Ta Xiao, Hong-Mei Yi, Zhen Zheng, Jia-Quan Qu, Wei Huang, Xu Ye, Hong Yi, Shan-Shan Lu, Xin-Hui Li, Zhi-Qiang Xiao
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (11): 2490.
https://doi.org/10.1158/1535-7163.MCT-18-0938
Published: 02 November 2018
View articletitled, Retraction: MiR-125b Increases Nasopharyngeal Carcinoma Radioresistance By Targeting A20/NF-κB Signaling Pathway
Open the PDF for Retraction: MiR-125b Increases Nasopharyngeal Carcinoma Radioresistance By Targeting A20/NF-κB Signaling Pathway in another window
Journal Articles

MiR-125b Increases Nasopharyngeal Carcinoma Radioresistance by Targeting A20/NF-κB Signaling Pathway

Free
Li-Na Li, Ta Xiao, Hong-Mei Yi, Zhen Zheng, Jia-Quan Qu, Wei Huang, Xu Ye, Hong Yi, Shan-Shan Lu, Xin-Hui Li, Zhi-Qiang Xiao
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2017) 16 (10): 2094–2106.
https://doi.org/10.1158/1535-7163.MCT-17-0385
Published: 02 October 2017
View articletitled, MiR-125b Increases Nasopharyngeal Carcinoma Radioresistance by Targeting A20/NF-κB Signaling Pathway
Open the PDF for MiR-125b Increases Nasopharyngeal Carcinoma Radioresistance by Targeting A20/NF-κB Signaling Pathway in another window
Includes: Supplementary data
Journal Articles

Expression of GRP78, Master Regulator of the Unfolded Protein Response, Increases Chemoresistance in Pancreatic Ductal Adenocarcinoma

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Jenifer B. Gifford, Wei Huang, Ann E. Zeleniak, Antreas Hindoyan, Hong Wu, Timothy R. Donahue, Reginald Hill
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2016) 15 (5): 1043–1052.
https://doi.org/10.1158/1535-7163.MCT-15-0774
Published: 05 May 2016
View articletitled, Expression of GRP78, Master Regulator of the Unfolded Protein Response, Increases Chemoresistance in Pancreatic Ductal Adenocarcinoma
Open the PDF for Expression of GRP78, Master Regulator of the Unfolded Protein Response, Increases Chemoresistance in Pancreatic Ductal Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

D-501036, a novel selenophene-based triheterocycle derivative, exhibits potent in vitro and in vivo antitumoral activity which involves DNA damage and ataxia telangiectasia–mutated nuclear protein kinase activation

Free
Shin-Hun Juang, Chia-Chi Lung, Pi-Chen Hsu, Kuo-Shun Hsu, Yu-Chen Li, Pao-Chiung Hong, Her-Shyong Shiah, Ching-Chuan Kuo, Ching-Wei Huang, Yu-Chin Wang, Leeyuan Huang, Tom S. Chen, Shyh-Fong Chen, Kuo-Chu Fu, Cheng-Li Hsu, Meng-Ju Lin, Ching-jer Chang, Curtis L. Ashendel, Thomas C.K. Chan, Kai-Ming Chou, Jang-Yang Chang
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (1): 193–202.
https://doi.org/10.1158/1535-7163.MCT-06-0482
Published: 19 January 2007
View articletitled, D-501036, a novel selenophene-based triheterocycle derivative, exhibits potent in vitro and in vivo antitumoral activity which involves DNA damage and ataxia telangiectasia–mutated nuclear protein kinase activation
Open the PDF for D-501036, a novel selenophene-based triheterocycle derivative, exhibits potent in vitro and in vivo antitumoral activity which involves DNA damage and ataxia telangiectasia–mutated nuclear protein kinase activation in another window