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Wataru Okamoto
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Journal Articles

Abstract A241: Differential roles of STAT3 depending on the mechanism of STAT3 activation in gastric cancer cells.

Wataru Okamoto, Isamu Okamoto, Katsuya Tuchihara, Kazuyoshi Yanagihara, Kazuto Nishio, Kazuhiko Nakagawa
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11_Supplement): A241.
https://doi.org/10.1158/1535-7163.TARG-13-A241
Published: 01 November 2013
View article titled, Abstract A241: Differential roles of STAT3 depending on the mechanism of STAT3 activation in gastric cancer cells.
Journal Articles

Abstract B29: Feasibility of amplicon sequencing using a pan-cancer gene panel with pre-treatment biopsy samples of (Japanese) patients with advanced solid tumors: Analyses of Biopsy Samples for Cancer Genomics (ABC) study.

Hideaki Takahashi, Kohei Shitara, Takeshi Kuwata, Yoichi Naito, Shingo Matsumoto, Wataru Okamoto, Seiji Niho, Hideaki Bando, Yasutoshi Kuboki, Yoko Yamada, Izumi Miki, Takeharu Yamanaka, Atsushi Watanabe, Motohiro Kojima, Genichiro Ishii, Satoshi Fujii, Shigeki Umemura, Masafumi Ikeda, Takashi Kohno, Akihiro Sato, Atsushi Ohtsu, Hiroyasu Esumi, Atsushi Ochiai, Takayuki Yoshino, Katsuya Tsuchihara
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11_Supplement): B29.
https://doi.org/10.1158/1535-7163.TARG-13-B29
Published: 01 November 2013
View article titled, Abstract B29: Feasibility of amplicon sequencing using a pan-cancer gene panel with pre-treatment biopsy samples of (Japanese) patients with advanced solid tumors: Analyses of Biopsy Samples for Cancer Genomics (ABC) study.
Journal Articles

Antitumor Action of the MET Tyrosine Kinase Inhibitor Crizotinib (PF-02341066) in Gastric Cancer Positive for MET Amplification

Wataru Okamoto, Isamu Okamoto, Tokuzo Arao, Kiyoko Kuwata, Erina Hatashita, Haruka Yamaguchi, Kazuko Sakai, Kazuyoshi Yanagihara, Kazuto Nishio, Kazuhiko Nakagawa
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2012) 11 (7): 1557–1564.
https://doi.org/10.1158/1535-7163.MCT-11-0934
Published: 05 July 2012
View article titled, Antitumor Action of the MET Tyrosine Kinase Inhibitor Crizotinib (PF-02341066) in Gastric Cancer Positive for <em>MET</em> Amplification
Open the PDF for Antitumor Action of the MET Tyrosine Kinase Inhibitor Crizotinib (PF-02341066) in Gastric Cancer Positive for <em>MET</em> Amplification in another window
Includes: Supplementary data
Journal Articles

TAK-701, a Humanized Monoclonal Antibody to Hepatocyte Growth Factor, Reverses Gefitinib Resistance Induced by Tumor-Derived HGF in Non–Small Cell Lung Cancer with an EGFR Mutation

Wataru Okamoto, Isamu Okamoto, Kaoru Tanaka, Erina Hatashita, Yuki Yamada, Kiyoko Kuwata, Haruka Yamaguchi, Tokuzo Arao, Kazuto Nishio, Masahiro Fukuoka, Pasi A. Jänne, Kazuhiko Nakagawa
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2010) 9 (10): 2785–2792.
https://doi.org/10.1158/1535-7163.MCT-10-0481
Published: 10 October 2010
View article titled, TAK-701, a Humanized Monoclonal Antibody to Hepatocyte Growth Factor, Reverses Gefitinib Resistance Induced by Tumor-Derived HGF in Non–Small Cell Lung Cancer with an <em>EGFR</em> Mutation
Open the PDF for TAK-701, a Humanized Monoclonal Antibody to Hepatocyte Growth Factor, Reverses Gefitinib Resistance Induced by Tumor-Derived HGF in Non–Small Cell Lung Cancer with an <em>EGFR</em> Mutation in another window
Journal Articles

Phase I Safety, Pharmacokinetic, and Biomarker Study of BIBF 1120, an Oral Triple Tyrosine Kinase Inhibitor in Patients with Advanced Solid Tumors

Isamu Okamoto, Hiroyasu Kaneda, Taroh Satoh, Wataru Okamoto, Masaki Miyazaki, Ryotaro Morinaga, Shinya Ueda, Masaaki Terashima, Asuka Tsuya, Akiko Sarashina, Koichi Konishi, Tokuzo Arao, Kazuto Nishio, Rolf Kaiser, Kazuhiko Nakagawa
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2010) 9 (10): 2825–2833.
https://doi.org/10.1158/1535-7163.MCT-10-0379
Published: 10 October 2010
View article titled, Phase I Safety, Pharmacokinetic, and Biomarker Study of BIBF 1120, an Oral Triple Tyrosine Kinase Inhibitor in Patients with Advanced Solid Tumors
Open the PDF for Phase I Safety, Pharmacokinetic, and Biomarker Study of BIBF 1120, an Oral Triple Tyrosine Kinase Inhibitor in Patients with Advanced Solid Tumors in another window
Includes: Supplementary data
Journal Articles

Identification of c-Src as a Potential Therapeutic Target for Gastric Cancer and of MET Activation as a Cause of Resistance to c-Src Inhibition

Wataru Okamoto, Isamu Okamoto, Takeshi Yoshida, Kunio Okamoto, Ken Takezawa, Erina Hatashita, Yuki Yamada, Kiyoko Kuwata, Tokuzo Arao, Kazuyoshi Yanagihara, Masahiro Fukuoka, Kazuto Nishio, Kazuhiko Nakagawa
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2010) 9 (5): 1188–1197.
https://doi.org/10.1158/1535-7163.MCT-10-0002
Published: 09 May 2010
View article titled, Identification of c-Src as a Potential Therapeutic Target for Gastric Cancer and of MET Activation as a Cause of Resistance to c-Src Inhibition
Open the PDF for Identification of c-Src as a Potential Therapeutic Target for Gastric Cancer and of MET Activation as a Cause of Resistance to c-Src Inhibition in another window
Includes: Supplementary data