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Vinitha M. Kuruvilla
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Journal Articles

Maximal Activation of Apoptosis Signaling by Cotargeting Antiapoptotic Proteins in BH3 Mimetic–Resistant AML and AML Stem Cells

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Bing Z. Carter, Po Yee Mak, Wenjing Tao, Qi Zhang, Vivian Ruvolo, Vinitha M. Kuruvilla, Xiangmeng Wang, Duncan H. Mak, Venkata L. Battula, Marina Konopleva, Elias J. Jabbour, Paul E. Hughes, Xiaoyue Chen, Phuong K. Morrow, Michael Andreeff
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2022) 21 (6): 879–889.
https://doi.org/10.1158/1535-7163.MCT-21-0690
Published: 01 June 2022
View articletitled, Maximal Activation of Apoptosis Signaling by Cotargeting Antiapoptotic Proteins in BH3 Mimetic–Resistant AML and AML Stem Cells
Open the PDF for Maximal Activation of Apoptosis Signaling by Cotargeting Antiapoptotic Proteins in BH3 Mimetic–Resistant AML and AML Stem Cells in another window
Includes: Supplementary data
Journal Articles

Selective Inhibition of the Second Bromodomain of BET Family Proteins Results in Robust Antitumor Activity in Preclinical Models of Acute Myeloid Leukemia

Available to Purchase
Lu Zhang, Tianyu Cai, Xiaoyu Lin, Xiaoli Huang, Mai H. Bui, Joshua P. Plotnik, Richard J. Bellin, Emily J. Faivre, Vinitha M. Kuruvilla, Lloyd T. Lam, Xin Lu, Zheng Zha, Weiguo Feng, Paul Hessler, Tamar Uziel, Qi Zhang, Antonio Cavazos, Lina Han, Debra C. Ferguson, Gaurav Mehta, Sriram S. Shanmugavelandy, Terrance J. Magoc, Jenny Rowe, Neal C. Goodwin, Kathleen A. Dorritie, Michael Boyiadzis, Daniel H. Albert, Keith F. McDaniel, Warren M. Kati, Marina Konopleva, Yu Shen
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (10): 1809–1819.
https://doi.org/10.1158/1535-7163.MCT-21-0029
Published: 01 October 2021
View articletitled, Selective Inhibition of the Second Bromodomain of BET Family Proteins Results in Robust Antitumor Activity in Preclinical Models of Acute Myeloid Leukemia
Open the PDF for Selective Inhibition of the Second Bromodomain of BET Family Proteins Results in Robust Antitumor Activity in Preclinical Models of Acute Myeloid Leukemia in another window
Includes: Supplementary data