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Vaishali Shinde
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Journal Articles

Abstract A41: Automated immunohistochemistry of phosphobiomarkers: Case study of MTOR (MLN0128) and PI3Kα (MLN1117) investigational inhibitors, single agent and in combination, on xenografts and mouse skin

Anna Kreshock, Natalia Iartchouk, Yueying Cao, Jeffrey Szwaya, Feng Gao, Christopher Simpson, Evan Luongo, Kristine Burke, Esha Gangolli, Keisuke Kuida, Rachael Brake, Stephen Tirrell, Vaishali Shinde
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (7_Supplement): A41.
DOI: https://doi.org/10.1158/1538-8514.PI3K14-A41
Published: 06 July 2015
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Journal Articles

Translational Exposure–Efficacy Modeling to Optimize the Dose and Schedule of Taxanes Combined with the Investigational Aurora A Kinase Inhibitor MLN8237 (Alisertib)

Jessica J. Huck, Mengkun Zhang, Jerome Mettetal, Arijit Chakravarty, Karthik Venkatakrishnan, Xiaofei Zhou, Rob Kleinfield, Marc L. Hyer, Karuppiah Kannan, Vaishali Shinde, Andy Dorner, Mark G. Manfredi, Wen Chyi Shyu, Jeffrey A. Ecsedy
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2014) 13 (9): 2170–2183.
DOI: https://doi.org/10.1158/1535-7163.MCT-14-0027
Published: 02 September 2014
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Includes: Supplementary data
Journal Articles

Response to MLN8237 in Pancreatic Cancer Is Not Dependent on RalA Phosphorylation

Nicole F. Neel, Jeran K. Stratford, Vaishali Shinde, Jeffrey A. Ecsedy, Timothy D. Martin, Channing J. Der, Jen Jen Yeh
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2014) 13 (1): 122–133.
DOI: https://doi.org/10.1158/1535-7163.MCT-12-1232
Published: 13 January 2014
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Includes: Supplementary data
Journal Articles

MLN0905, a Small-Molecule PLK1 Inhibitor, Induces Antitumor Responses in Human Models of Diffuse Large B-cell Lymphoma

Judy Quiju Shi, Kerri Lasky, Vaishali Shinde, Bradley Stringer, Mark G. Qian, Debra Liao, Ray Liu, Denise Driscoll, Michelle Tighe Nestor, Benjamin S. Amidon, Youlan Rao, Matt O. Duffey, Mark G. Manfredi, Tricia J. Vos, Natalie D' Amore, Marc L. Hyer
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2012) 11 (9): 2045–2053.
DOI: https://doi.org/10.1158/1535-7163.MCT-11-1036
Published: 06 September 2012
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Includes: Supplementary data
Journal Articles

Abstract C188: RalA phosphorylation as a biomarker in pancreatic ductal adenocarcinoma for Aurora A kinase inhibition in response to the investigational agent MLN8237.

Nicole F. Neel, Jeffrey A. Escedy, Vaishali Shinde, Channing J. Der, Jen Jen Yeh
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (11_Supplement): C188.
DOI: https://doi.org/10.1158/1535-7163.TARG-11-C188
Published: 12 November 2011
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Journal Articles

Phase I Study of the Selective Aurora A Kinase Inhibitor MLN8054 in Patients with Advanced Solid Tumors: Safety, Pharmacokinetics, and Pharmacodynamics

Teresa Macarulla, Andres Cervantes, Elena Elez, Edith Rodríguez-Braun, José Baselga, Susana Roselló, Gemma Sala, Inma Blasco, Hadi Danaee, Yih Lee, Jeffrey Ecsedy, Vaishali Shinde, Arijit Chakravarty, Douglas Bowman, Hua Liu, Omar Eton, Howard Fingert, Josep Tabernero
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2010) 9 (10): 2844–2852.
DOI: https://doi.org/10.1158/1535-7163.MCT-10-0299
Published: 10 October 2010
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