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Toshiyuki Nomura
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Journal Articles

Abstract B060: Small molecule inhibitor of pre-mRNA splicing evokes antitumor activity via MDM4-p53 pathway

Kazuho Nishimura, Masahiro Yaguchi, Yukiko Yamamoto, Shunsuke Ebara, Kawakita Yoichi, Ryo Mizojiri, Yusuke Nakayama, Kozo Hayashi, Shuichi Miyakawa, Kenichi Iwai, Toshiyuki Nomura
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (1_Supplement): B060.
https://doi.org/10.1158/1535-7163.TARG-17-B060
Published: 01 January 2018
View article titled, Abstract B060: Small molecule inhibitor of pre-mRNA splicing evokes antitumor activity via MDM4-p53 pathway
Journal Articles

A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells

Yoshinori Ishikawa, Kanae Gamo, Masato Yabuki, Shinji Takagi, Kosei Toyoshima, Kazuhide Nakayama, Akiko Nakayama, Megumi Morimoto, Hitoshi Miyashita, Ryo Dairiki, Yukiko Hikichi, Naoki Tomita, Daisuke Tomita, Shinichi Imamura, Misa Iwatani, Yusuke Kamada, Satoru Matsumoto, Ryujiro Hara, Toshiyuki Nomura, Ken Tsuchida, Kazuhide Nakamura
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2017) 16 (2): 273–284.
https://doi.org/10.1158/1535-7163.MCT-16-0471
Published: 02 February 2017
View article titled, A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells
Open the PDF for A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells in another window
Includes: Supplementary data
Journal Articles

Biological Characterization of TAK-901, an Investigational, Novel, Multitargeted Aurora B Kinase Inhibitor

Pamela Farrell, Lihong Shi, Jennifer Matuszkiewicz, Deepika Balakrishna, Takashi Hoshino, Lilly Zhang, Sarah Elliott, Robyn Fabrey, Bumsup Lee, Petro Halkowycz, BiChing Sang, Seigo Ishino, Toshiyuki Nomura, Mika Teratani, Yoshikazu Ohta, Charles Grimshaw, Bheema Paraselli, Takashi Satou, Ron de Jong
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (4): 460–470.
https://doi.org/10.1158/1535-7163.MCT-12-0657
Published: 08 April 2013
View article titled, Biological Characterization of TAK-901, an Investigational, Novel, Multitargeted Aurora B Kinase Inhibitor
Open the PDF for Biological Characterization of TAK-901, an Investigational, Novel, Multitargeted Aurora B Kinase Inhibitor in another window
Includes: Supplementary data
Journal Articles

Abstract C193: Biological evaluation of novel multi‐targeted Aurora‐B kinase inhibitor TAK‐901 in xenograft models

Takashi Satou, Takashi Hoshino, Pamela Farrell, Lilly Zhang, Sarah Elliott, Robyn Fabrey, Bumsup Lee, Bheema Paraselli, Seigo Ishino, Toshiyuki Nomura, Mika Teratani, Yoshikazu Ohta, Ron de Jong
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (12_Supplement): C193.
https://doi.org/10.1158/1535-7163.TARG-09-C193
Published: 10 December 2009
View article titled, Abstract C193: Biological evaluation of novel multi‐targeted Aurora‐B kinase inhibitor TAK‐901 in xenograft models