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Tinya J. Abrams
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Journal Articles

PCA062, a P-cadherin Targeting Antibody–Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin–expressing Malignancies

Qing Sheng, Joseph A. D'Alessio, Daniel L. Menezes, Christopher Karim, Yan Tang, Angela Tam, Suzanna Clark, Chi Ying, Anu Connor, Keith G. Mansfield, Jean-Michel Rondeau, Majid Ghoddusi, Felipe C. Geyer, Jane Gu, Margaret E. McLaughlin, Rick Newcombe, GiNell Elliot, William R. Tschantz, Sylvie Lehmann, Christie P. Fanton, Kathy Miller, Thomas Huber, Katherine G. Rendahl, Ursula Jeffry, Nancy K. Pryer, Emma Lees, Paul Kwon, Judith A. Abraham, Jason S. Damiano, Tinya J. Abrams
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (7): 1270–1282.
https://doi.org/10.1158/1535-7163.MCT-20-0708
Published: 01 July 2021
View article titled, PCA062, a P-cadherin Targeting Antibody–Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin–expressing Malignancies
Open the PDF for PCA062, a P-cadherin Targeting Antibody–Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin–expressing Malignancies in another window
Includes: Supplementary data
Journal Articles

Tumor Intrinsic Efficacy by SHP2 and RTK Inhibitors in KRAS-Mutant Cancers

Huai-Xiang Hao, Hongyun Wang, Chen Liu, Steven Kovats, Roberto Velazquez, Hengyu Lu, Bhavesh Pant, Matthew Shirley, Matthew J. Meyer, Minying Pu, Joanne Lim, Michael Fleming, LeighAnn Alexander, Ali Farsidjani, Matthew J. LaMarche, Susan Moody, Serena J. Silver, Giordano Caponigro, Darrin D. Stuart, Tinya J. Abrams, Peter S. Hammerman, Juliet Williams, Jeffrey A. Engelman, Silvia Goldoni, Morvarid Mohseni
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (12): 2368–2380.
https://doi.org/10.1158/1535-7163.MCT-19-0170
Published: 02 December 2019
View article titled, Tumor Intrinsic Efficacy by SHP2 and RTK Inhibitors in KRAS-Mutant Cancers
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Includes: Supplementary data
Journal Articles

Neutralization of Prolactin Receptor Function by Monoclonal Antibody LFA102, a Novel Potential Therapeutic for the Treatment of Breast Cancer

Jason S. Damiano, Katherine G. Rendahl, Christopher Karim, Millicent G. Embry, Majid Ghoddusi, Jocelyn Holash, Abdallah Fanidi, Tinya J. Abrams, Judith A. Abraham
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (3): 295–305.
https://doi.org/10.1158/1535-7163.MCT-12-0886
Published: 10 March 2013
View article titled, Neutralization of Prolactin Receptor Function by Monoclonal Antibody LFA102, a Novel Potential Therapeutic for the Treatment of Breast Cancer
Open the PDF for Neutralization of Prolactin Receptor Function by Monoclonal Antibody LFA102, a Novel Potential Therapeutic for the Treatment of Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Preclinical evaluation of the tyrosine kinase inhibitor SU11248 as a single agent and in combination with “standard of care” therapeutic agents for the treatment of breast cancer

Tinya J. Abrams, Lesley J. Murray, Enrico Pesenti, Vicky Walker Holway, Tina Colombo, Leslie B. Lee, Julie M. Cherrington, Nancy K. Pryer
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2003) 2 (10): 1011–1021.
Published: 24 October 2003
View article titled, Preclinical evaluation of the tyrosine kinase inhibitor SU11248 as a single agent and in combination with “standard of care” therapeutic agents for the treatment of breast cancer
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Journal Articles

SU11248 Inhibits KIT and Platelet-derived Growth Factor Receptor β in Preclinical Models of Human Small Cell Lung Cancer

Tinya J. Abrams, Leslie B. Lee, Lesley J. Murray, Nancy K. Pryer, Julie M. Cherrington
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2003) 2 (5): 471–478.
Published: 01 May 2003
View article titled, SU11248 Inhibits KIT and Platelet-derived Growth Factor Receptor β in Preclinical Models of Human Small Cell Lung Cancer
Open the PDF for SU11248 Inhibits KIT and Platelet-derived Growth Factor Receptor β in Preclinical Models of Human Small Cell Lung Cancer in another window