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Theodore S. Lawrence
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Journal Articles

Olaparib and Radiotherapy Induce Type I Interferon– and CD8+ T Cell–Dependent Sensitization to Immunotherapy in Pancreatic Cancer

Victoria M. Valvo, Qiang Zhang, Long Jiang, Erin A. Holcomb, Ashley N. Pearson, Anna G. Edmunds, Hailey G. Faulkner, Jadyn G. James, Akshay Tate, Amanda K. Huber, Zhuwen Wang, Yupei Guo, David Karnak, Leslie A. Parsels, Joshua D. Parsels, Yu L. Lei, Alnawaz Rehemtulla, Heng Lin, Eileen S. Carpenter, Daniel R. Wahl, Vaibhav Sahai, Theodore S. Lawrence, Michael D. Green, Meredith A. Morgan
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther OF1–OF16.
https://doi.org/10.1158/1535-7163.MCT-24-0210
Published: 17 December 2024
View article titled, Olaparib and Radiotherapy Induce Type I Interferon– and CD8<sup>+</sup> T Cell–Dependent Sensitization to Immunotherapy in Pancreatic Cancer
Open the PDF for Olaparib and Radiotherapy Induce Type I Interferon– and CD8<sup>+</sup> T Cell–Dependent Sensitization to Immunotherapy in Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Combinatorial Efficacy of Olaparib with Radiation and ATR Inhibitor Requires PARP1 Protein in Homologous Recombination–Proficient Pancreatic Cancer

Leslie A. Parsels, Carl G. Engelke, Joshua Parsels, Sheryl A. Flanagan, Qiang Zhang, Daria Tanska, Daniel R. Wahl, Christine E. Canman, Theodore S. Lawrence, Meredith A. Morgan
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (2): 263–273.
https://doi.org/10.1158/1535-7163.MCT-20-0365
Published: 05 February 2021
View article titled, Combinatorial Efficacy of Olaparib with Radiation and ATR Inhibitor Requires PARP1 Protein in Homologous Recombination–Proficient Pancreatic Cancer
Open the PDF for Combinatorial Efficacy of Olaparib with Radiation and ATR Inhibitor Requires PARP1 Protein in Homologous Recombination–Proficient Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Expression of the Androgen Receptor Governs Radiation Resistance in a Subset of Glioblastomas Vulnerable to Antiandrogen Therapy

Christian K. Werner, Uchechi J. Nna, Hanshi Sun, Kari Wilder-Romans, Joseph Dresser, Ayesha U. Kothari, Weihua Zhou, Yangyang Yao, Arvind Rao, Stefanie Stallard, Carl Koschmann, Tarik Bor, Waldemar Debinski, Alexander M. Hegedus, Meredith A. Morgan, Sriram Venneti, Edwina Baskin-Bey, Daniel E. Spratt, Howard Colman, Jann N. Sarkaria, Arul M. Chinnaiyan, Joel R. Eisner, Corey Speers, Theodore S. Lawrence, Roy E. Strowd, Daniel R. Wahl
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2020) 19 (10): 2163–2174.
https://doi.org/10.1158/1535-7163.MCT-20-0095
Published: 02 October 2020
View article titled, Expression of the Androgen Receptor Governs Radiation Resistance in a Subset of Glioblastomas Vulnerable to Antiandrogen Therapy
Open the PDF for Expression of the Androgen Receptor Governs Radiation Resistance in a Subset of Glioblastomas Vulnerable to Antiandrogen Therapy in another window
Includes: Supplementary data
Journal Articles

Cotargeting MAPK and PI3K Signaling with Concurrent Radiotherapy as a Strategy for the Treatment of Pancreatic Cancer

Terence M. Williams, Athena R. Flecha, Paul Keller, Ashwin Ram, David Karnak, Stefanie Galbán, Craig J. Galbán, Brian D. Ross, Theodore S. Lawrence, Alnawaz Rehemtulla, Judith Sebolt-Leopold
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2012) 11 (5): 1193–1202.
https://doi.org/10.1158/1535-7163.MCT-12-0098
Published: 08 May 2012
View article titled, Cotargeting MAPK and PI3K Signaling with Concurrent Radiotherapy as a Strategy for the Treatment of Pancreatic Cancer
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Includes: Supplementary data
Journal Articles

Radiosensitization of Head and Neck Squamous Cell Carcinoma by a SMAC-Mimetic Compound, SM-164, Requires Activation of Caspases

Jie Yang, Donna McEachern, Wenyan Li, Mary A. Davis, Hua Li, Meredith A. Morgan, Longchuan Bai, Jonathan T. Sebolt, Haiying Sun, Theodore S. Lawrence, Shaomeng Wang, Yi Sun
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (4): 658–669.
https://doi.org/10.1158/1535-7163.MCT-10-0643
Published: 06 April 2011
View article titled, Radiosensitization of Head and Neck Squamous Cell Carcinoma by a SMAC-Mimetic Compound, SM-164, Requires Activation of Caspases
Open the PDF for Radiosensitization of Head and Neck Squamous Cell Carcinoma by a SMAC-Mimetic Compound, SM-164, Requires Activation of Caspases in another window
Includes: Supplementary data
Journal Articles

Abstract A53: Tumor suppressor microRNA miR‐34 inhibits human pancreatic and gastric cancer stem cells

Liang Xu, Qing Ji, Xinbao Hao, Wenhua Tang, Ling Li, Jeffrey T. DeSano, Eric R. Fearon, Theodore S. Lawrence
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (12_Supplement): A53.
https://doi.org/10.1158/1535-7163.TARG-09-A53
Published: 10 December 2009
View article titled, Abstract A53: Tumor suppressor microRNA miR‐34 inhibits human pancreatic and gastric cancer stem cells
Journal Articles

Gemcitabine sensitization by checkpoint kinase 1 inhibition correlates with inhibition of a Rad51 DNA damage response in pancreatic cancer cells

Leslie A. Parsels, Meredith A. Morgan, Daria M. Tanska, Joshua D. Parsels, Brian D. Palmer, R. John Booth, William A. Denny, Christine E. Canman, Alan J. Kraker, Theodore S. Lawrence, Jonathan Maybaum
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (1): 45–54.
https://doi.org/10.1158/1535-7163.MCT-08-0662
Published: 12 January 2009
View article titled, Gemcitabine sensitization by checkpoint kinase 1 inhibition correlates with inhibition of a Rad51 DNA damage response in pancreatic cancer cells
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Includes: Supplementary data
Journal Articles

Evaluation of Cancer Therapy Using Diffusion Magnetic Resonance Imaging

Brian D. Ross, Bradford A. Moffat, Theodore S. Lawrence, Suresh K. Mukherji, Stephen S. Gebarski, Douglas J. Quint, Timothy D. Johnson, Larry Junck, Patricia L. Robertson, Karin M. Muraszko, Qian Dong, Charles R. Meyer, Peyton H. Bland, Patrick McConville, Hairong Geng, Alnawaz Rehemtulla, Thomas L. Chenevert
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2003) 2 (6): 581–587.
Published: 01 June 2003
View article titled, Evaluation of Cancer Therapy Using Diffusion Magnetic Resonance Imaging
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