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Teru Hideshima
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Journal Articles

Delineating the mTOR Kinase Pathway Using a Dual TORC1/2 Inhibitor, AZD8055, in Multiple Myeloma

Diana Cirstea, Loredana Santo, Teru Hideshima, Homare Eda, Yuko Mishima, Neeharika Nemani, Anuj Mahindra, Andrew Yee, Gullu Gorgun, Yiguo Hu, Hiroto Ohguchi, Rikio Suzuki, Francesca Cottini, Sylvie M. Guichard, Kenneth C. Anderson, Noopur Raje
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2014) 13 (11): 2489–2500.
https://doi.org/10.1158/1535-7163.MCT-14-0147
Published: 03 November 2014
View article titled, Delineating the mTOR Kinase Pathway Using a Dual TORC1/2 Inhibitor, AZD8055, in Multiple Myeloma
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Includes: Supplementary data
Journal Articles

Mechanism of Action of Proteasome Inhibitors and Deacetylase Inhibitors and the Biological Basis of Synergy in Multiple Myeloma

Teru Hideshima, Paul G. Richardson, Kenneth C. Anderson
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (11): 2034–2042.
https://doi.org/10.1158/1535-7163.MCT-11-0433
Published: 08 November 2011
View article titled, Mechanism of Action of Proteasome Inhibitors and Deacetylase Inhibitors and the Biological Basis of Synergy in Multiple Myeloma
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Journal Articles

Dual Inhibition of Akt/Mammalian Target of Rapamycin Pathway by Nanoparticle Albumin-Bound–Rapamycin and Perifosine Induces Antitumor Activity in Multiple Myeloma

Diana Cirstea, Teru Hideshima, Scott Rodig, Loredana Santo, Samantha Pozzi, Sonia Vallet, Hiroshi Ikeda, Giulia Perrone, Gullu Gorgun, Kishan Patel, Neil Desai, Peter Sportelli, Shweta Kapoor, Shireen Vali, Siddhartha Mukherjee, Nikhil C. Munshi, Kenneth C. Anderson, Noopur Raje
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2010) 9 (4): 963–975.
https://doi.org/10.1158/1535-7163.MCT-09-0763
Published: 07 April 2010
View article titled, Dual Inhibition of Akt/Mammalian Target of Rapamycin Pathway by <em>Nanoparticle Albumin-Bound</em>–Rapamycin and Perifosine Induces Antitumor Activity in Multiple Myeloma
Open the PDF for Dual Inhibition of Akt/Mammalian Target of Rapamycin Pathway by <em>Nanoparticle Albumin-Bound</em>–Rapamycin and Perifosine Induces Antitumor Activity in Multiple Myeloma in another window
Includes: Supplementary data
Journal Articles

Janus kinase inhibitor INCB20 has antiproliferative and apoptotic effects on human myeloma cells in vitro and in vivo

Renate Burger, Steven Le Gouill, Yu-Tzu Tai, Reshma Shringarpure, Pierfrancesco Tassone, Paola Neri, Klaus Podar, Laurence Catley, Teru Hideshima, Dharminder Chauhan, Eian Caulder, Claire L. Neilan, Kris Vaddi, Jun Li, Martin Gramatzki, Jordan S. Fridman, Kenneth C. Anderson
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (1): 26–35.
https://doi.org/10.1158/1535-7163.MCT-08-0149
Published: 12 January 2009
View article titled, Janus kinase inhibitor INCB20 has antiproliferative and apoptotic effects on human myeloma cells <em>in vitro</em> and <em>in vivo</em>
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Journal Articles

5-Azacytidine, a DNA methyltransferase inhibitor, induces ATR-mediated DNA double-strand break responses, apoptosis, and synergistic cytotoxicity with doxorubicin and bortezomib against multiple myeloma cells

Tanyel Kiziltepe, Teru Hideshima, Laurence Catley, Noopur Raje, Hiroshi Yasui, Norihiko Shiraishi, Yutaka Okawa, Hiroshi Ikeda, Sonia Vallet, Samantha Pozzi, Kenji Ishitsuka, Enrique M. Ocio, Dharminder Chauhan, Kenneth C. Anderson
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (6): 1718–1727.
https://doi.org/10.1158/1535-7163.MCT-07-0010
Published: 15 June 2007
View article titled, 5-Azacytidine, a DNA methyltransferase inhibitor, induces ATR-mediated DNA double-strand break responses, apoptosis, and synergistic cytotoxicity with doxorubicin and bortezomib against multiple myeloma cells
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Journal Articles

Proteasome inhibitor therapy in multiple myeloma

Dharminder Chauhan, Teru Hideshima, Constantine Mitsiades, Paul Richardson, Kenneth C. Anderson
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2005) 4 (4): 686–692.
https://doi.org/10.1158/1535-7163.MCT-04-0338
Published: 12 April 2005
View article titled, Proteasome inhibitor therapy in multiple myeloma
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Journal Articles

Telomerase inhibition and cell growth arrest by G-quadruplex interactive agent in multiple myeloma

Masood A. Shammas, Robert J. Shmookler Reis, Masaharu Akiyama, Hemanta Koley, Dharminder Chauhan, Teru Hideshima, Raj K. Goyal, Laurence H. Hurley, Kenneth C. Anderson, Nikhil C. Munshi
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2003) 2 (9): 825–833.
Published: 10 October 2003
View article titled, Telomerase inhibition and cell growth arrest by G-quadruplex interactive agent in multiple myeloma
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Journal Articles

Arsenic Trioxide Inhibits Growth of Human Multiple Myeloma Cells in the Bone Marrow Microenvironment

Toshiaki Hayashi, Teru Hideshima, Masaharu Akiyama, Paul Richardson, Robert L. Schlossman, Dharminder Chauhan, Nikhil C. Munshi, Samuel Waxman, Kenneth C. Anderson
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2002) 1 (10): 851–860.
Published: 01 August 2002
View article titled, Arsenic Trioxide Inhibits Growth of Human Multiple Myeloma Cells in the Bone Marrow Microenvironment
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Journal Articles

The Biological Sequelae of Stromal Cell-derived Factor-1α in Multiple Myeloma

Teru Hideshima, Dharminder Chauhan, Toshiaki Hayashi, Klaus Podar, Masaharu Akiyama, Deepak Gupta, Paul Richardson, Nikhil Munshi, Kenneth C. Anderson
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2002) 1 (7): 539–544.
Published: 01 May 2002
View article titled, The Biological Sequelae of Stromal Cell-derived Factor-1α in Multiple Myeloma
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