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Takuya Osada
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Journal Articles

HSP90-Specific nIR Probe Identifies Aggressive Prostate Cancers: Translation from Preclinical Models to a Human Phase I Study

Takuya Osada, Erika J. Crosby, Kensuke Kaneko, Joshua C. Snyder, Joshua D. Ginzel, Chaitanya R. Acharya, Xiao-Yi Yang, Thomas J. Polascik, Ivan Spasojevic, Rendon C. Nelson, Amy Hobeika, Zachary C. Hartman, Leonard M. Neckers, Andre Rogatko, Philip F. Hughes, Jiaoti Huang, Michael A. Morse, Timothy Haystead, H. Kim Lyerly
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2022) 21 (1): 217–226.
https://doi.org/10.1158/1535-7163.MCT-21-0334
Published: 01 January 2022
View article titled, HSP90-Specific nIR Probe Identifies Aggressive Prostate Cancers: Translation from Preclinical Models to a Human Phase I Study
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Journal Articles

Abstract C86: Tethered Hsp90 inhibitors carrying optical or radioiodinated probes reveal selective internalization of ectopic Hsp90 in malignant breast tumor cells.

Jared J. Barrott, Aaron P. Smith, Takuya Osada, Nimmi Ramanujam, Michael R. Zalutsky, Kim Lyerly, Timothy A. J. Haystead
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11_Supplement): C86.
https://doi.org/10.1158/1535-7163.TARG-13-C86
Published: 01 November 2013
View article titled, Abstract C86: Tethered Hsp90 inhibitors carrying optical or radioiodinated probes reveal selective internalization of ectopic Hsp90 in malignant breast tumor cells.
Journal Articles

Characterization of an Oxaliplatin Sensitivity Predictor in a Preclinical Murine Model of Colorectal Cancer

Mickey K. Kim, Takuya Osada, William T. Barry, Xiao Yi Yang, Jennifer A. Freedman, Katherine A. Tsamis, Michael Datto, Bryan M. Clary, Timothy Clay, Michael A. Morse, Philip G. Febbo, H. Kim Lyerly, David S. Hsu
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2012) 11 (7): 1500–1509.
https://doi.org/10.1158/1535-7163.MCT-11-0937
Published: 05 July 2012
View article titled, Characterization of an Oxaliplatin Sensitivity Predictor in a Preclinical Murine Model of Colorectal Cancer
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Includes: Supplementary data
Journal Articles

Truncated ErbB2 Expressed in Tumor Cell Nuclei Contributes to Acquired Therapeutic Resistance to ErbB2 Kinase Inhibitors

Wenle Xia, Zuguo Liu, Rongrong Zong, Leihua Liu, Sumin Zhao, Sarah S. Bacus, Yubin Mao, Jia He, Julia D. Wulfkuhle, Emanuel F. Petricoin, III, Takuya Osada, Xiao-Yi Yang, Zachary C. Hartman, Timothy M. Clay, Kimberly L. Blackwell, Herbert K. Lyerly, Neil L. Spector
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (8): 1367–1374.
https://doi.org/10.1158/1535-7163.MCT-10-0991
Published: 08 August 2011
View article titled, Truncated ErbB2 Expressed in Tumor Cell Nuclei Contributes to Acquired Therapeutic Resistance to ErbB2 Kinase Inhibitors
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