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Journal Articles

The rexinoid LG100268 and the synthetic triterpenoid CDDO-methyl amide are more potent than erlotinib for prevention of mouse lung carcinogenesis

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Karen Liby, Candice C. Black, Darlene B. Royce, Charlotte R. Williams, Renee Risingsong, Mark M. Yore, Xi Liu, Tadashi Honda, Gordon W. Gribble, William W. Lamph, Thomas A. Sporn, Ethan Dmitrovsky, Michael B. Sporn
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (5): 1251–1257.
https://doi.org/10.1158/1535-7163.MCT-08-0023
Published: 15 May 2008
View article titled, The rexinoid LG100268 and the synthetic triterpenoid CDDO-methyl amide are more potent than erlotinib for prevention of mouse lung carcinogenesis
Open the PDF for The rexinoid LG100268 and the synthetic triterpenoid CDDO-methyl amide are more potent than erlotinib for prevention of mouse lung carcinogenesis in another window
Journal Articles

A novel synthetic tricyclic compound with an acetylene group at C-8a and cyano enones in rings A and C is a potent multifunctional agent in vitro and suppresses the formation of aflatoxin-DNA adducts in vivo

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Karen Liby, Tadashi Honda, Mark Yore, Chitra Sundararajan, Hidenori Yoshizawa, Renee Risingsong, Charlotte Williams, Darlene Royce, Albena Dinkova-Kostova, Katherine Stephenson, Patricia Egner, Melinda Yates, John Groopman, Thomas Kensler, B Roebuck, Gordon Gribble, Michael Sporn
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (11_Supplement): B66.
Published: 01 November 2007
View article titled, A novel synthetic tricyclic compound with an acetylene group at C-8a and cyano enones in rings A and C is a potent multifunctional agent in vitro and suppresses the formation of aflatoxin-DNA adducts in vivo
Journal Articles

Novel semisynthetic analogues of betulinic acid with diverse cytoprotective, antiproliferative, and proapoptotic activities

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Karen Liby, Tadashi Honda, Charlotte R. Williams, Renee Risingsong, Darlene B. Royce, Nanjoo Suh, Albena T. Dinkova-Kostova, Katherine K. Stephenson, Paul Talalay, Chitra Sundararajan, Gordon W. Gribble, Michael B. Sporn
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (7): 2113–2119.
https://doi.org/10.1158/1535-7163.MCT-07-0180
Published: 09 July 2007
View article titled, Novel semisynthetic analogues of betulinic acid with diverse cytoprotective, antiproliferative, and proapoptotic activities
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Journal Articles

Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes

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Melinda S. Yates, Masafumi Tauchi, Fumiki Katsuoka, Kathleen C. Flanders, Karen T. Liby, Tadashi Honda, Gordon W. Gribble, Delinda A. Johnson, Jeffrey A. Johnson, Neal C. Burton, Tomás R. Guilarte, Masayuki Yamamoto, Michael B. Sporn, Thomas W. Kensler
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (1): 154–162.
https://doi.org/10.1158/1535-7163.MCT-06-0516
Published: 19 January 2007
View article titled, Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes
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Journal Articles

The synthetic triterpenoid 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole blocks nuclear factor-κB activation through direct inhibition of IκB kinase β

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Mark M. Yore, Karen T. Liby, Tadashi Honda, Gordon W. Gribble, Michael B. Sporn
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2006) 5 (12): 3232–3239.
https://doi.org/10.1158/1535-7163.MCT-06-0444
Published: 15 December 2006
View article titled, The synthetic triterpenoid 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole blocks nuclear factor-κB activation through direct inhibition of IκB kinase β
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Journal Articles

Identification of a Novel Synthetic Triterpenoid, Methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate, That Potently Induces Caspase-mediated Apoptosis in Human Lung Cancer Cells

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Kevin B. Kim, Reuben Lotan, Ping Yue, Michael B. Sporn, Nanjoo Suh, Gordon W. Gribble, Tadashi Honda, Gen Sheng Wu, Waun Ki Hong, Shi-Yong Sun
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2002) 1 (3): 177–184.
Published: 01 January 2002
View article titled, Identification of a Novel Synthetic Triterpenoid, Methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate, That Potently Induces Caspase-mediated Apoptosis in Human Lung Cancer Cells
Open the PDF for Identification of a Novel Synthetic Triterpenoid, Methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate, That Potently Induces Caspase-mediated Apoptosis in Human Lung Cancer Cells in another window