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Stephen Yu
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Journal Articles

HPN328, a Trispecific T Cell–Activating Protein Construct Targeting DLL3-Expressing Solid Tumors

Open Access
Mary E. Molloy, Wade H. Aaron, Manasi Barath, Mabel C. Bush, Evan C. Callihan, Kevin Carlin, Michael Cremin, Thomas Evans, Maria G. Guerrero, Golzar Hemmati, Avneel S. Hundal, Llewelyn Lao, Payton Laurie, Bryan D. Lemon, S.J. Lin, Jessica O’Rear, Purbasa Patnaik, Sony Sotelo Rocha, Linda Santiago, Kathryn L. Strobel, Laura B. Valenzuela, Chi-Heng Wu, Stephen Yu, Timothy Z. Yu, Banmeet S. Anand, Che-Leung Law, Liping L. Sun, Holger Wesche, Richard J. Austin
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2024) 23 (9): 1294–1304.
https://doi.org/10.1158/1535-7163.MCT-23-0524
Published: 04 September 2024
View articletitled, HPN328, a Trispecific T Cell–Activating Protein Construct Targeting DLL3-Expressing Solid Tumors
Open the PDF for HPN328, a Trispecific T Cell–Activating Protein Construct Targeting DLL3-Expressing Solid Tumors in another window
Includes: Supplementary data
Journal Articles

TriTACs, a Novel Class of T-Cell–Engaging Protein Constructs Designed for the Treatment of Solid Tumors

Free
Richard J. Austin, Bryan D. Lemon, Wade H. Aaron, Manasi Barath, Patricia A. Culp, Robert B. DuBridge, Luke B. Evnin, Adrie Jones, Anand Panchal, Purbasa Patnaik, Vanitha Ramakrishnan, Sony S. Rocha, Pui Seto, Kenneth Sexton, Kathryn L. Strobel, Russell Wall, Stephen Yu, Timothy Z. Yu, Che-Leung Law, Patrick A. Baeuerle, Holger Wesche
Journal: Molecular Cancer Therapeutics
Series: Author Choice
Mol Cancer Ther (2021) 20 (1): 109–120.
https://doi.org/10.1158/1535-7163.MCT-20-0061
Published: 05 January 2021
View articletitled, TriTACs, a Novel Class of T-Cell–Engaging Protein Constructs Designed for the Treatment of Solid Tumors
Open the PDF for TriTACs, a Novel Class of T-Cell–Engaging Protein Constructs Designed for the Treatment of Solid Tumors in another window
Includes: Supplementary data
Journal Articles

Abstract C033: HPN328: An anti-DLL3 T cell engager for treatment of small cell lung cancer

Free
Wade H Aaron, Richard Austin, Manasi Barath, Evan Callihan, Michael Cremin, Thomas Evans, Maria Gamez, Vaishnavi Ganti, Golzar Hemmati, Kathryn Kwant, Che-Leung Law, Bryan Lemon, Llewelyn Lao, Mary Ellen Molloy, Jessica O’Rear, Laura Sun, Holger Wesche, Stephen Yu, Timothy Yu
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (12_Supplement): C033.
https://doi.org/10.1158/1535-7163.TARG-19-C033
Published: 01 December 2019
View articletitled, Abstract C033: HPN328: An anti-DLL3 T cell engager for treatment of small cell lung cancer
Journal Articles

Histone Deacetylase Inhibitor Entinostat Inhibits Tumor-Initiating Cells in Triple-Negative Breast Cancer Cells

Free
Amanda Schech, Armina Kazi, Stephen Yu, Preeti Shah, Gauri Sabnis
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (8): 1848–1857.
https://doi.org/10.1158/1535-7163.MCT-14-0778
Published: 05 August 2015
View articletitled, Histone Deacetylase Inhibitor Entinostat Inhibits Tumor-Initiating Cells in Triple-Negative Breast Cancer Cells
Open the PDF for Histone Deacetylase Inhibitor Entinostat Inhibits Tumor-Initiating Cells in Triple-Negative Breast Cancer Cells in another window
Includes: Supplementary data